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Protein Overview: Es2-PA

General Information:
Name(s) found: Es2-PA / FBpp0071145 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Es2 is referred to in FlyBase by the symbol Dmel\Es2 (CG1474, FBgn0023506). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8355509..8357418. It has the cytological map location 7E11. Based on sequence similarity, it is predicted to have molecular function</span>: sepiapterin reductase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nervous system development. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 501 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS][NAS]
    catalytic step 2 spliceosome [IDA]
    Biological Process: nervous system development [ISS]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: sepiapterin reductase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATTRTPAT PGTPGTPGSL AMEVARVQNS ALAEFKKPTA MVRHKNKPKI LTEEKYIEEM  60
   61 SKIIQRDFFP DLERLRAQND YLDAESRRDF VQMAEIRERY SLGRISGTGR STSRRNNAMS 120
  121 PATFETPVSQ AKCSNTPLPN SRATDTPFST DGSEKSDAEG RDTTAKLSLD AFLQKYTSED 180
  181 NQSFQEIIET AEAKLRQKYA VLYNHEKLSA EQLQRALMLP SIETQFEEPD PLRKIETWNY 240
  241 TNMNSIMYVP DGVEYTEEER VQLAERKQSI QHNATRLPDE AKHREMDTKK LNDEVPQNGA 300
  301 GGATATPKVR GFDLLRSPSP RPGEAFSPIM TWGEIDGTPF RLDGGDTPLR PTQGPSFRIN 360
  361 ENSRRENIAI ALAERVSERM RNQKQMALDT ARRNIGSPLI RTNMERLASM SPAAQLLATG 420
  421 KLGIRGTPRL RHTPSPMSGR KRKVTPGVVR STNTPILGEP KPKQQAKIST PAKNVTIDTG 480
  481 STLTDDLLKI PTKRRTAADF F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..231] MSA 1.041966 View MSA. No confident structure predictions are available.
    2 View Details [232..322] deduced N/A No confident structure predictions are available.
    3 View Details [323..501] MSA 17.153997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle