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Protein Overview: FBpp0298283, CG1...

General Information:
Name(s) found: FBpp0298283 [FlyBase]
CG1632-PA / FBpp0071118 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • type=protein; loc=X:join(8147457..8147489,8158122..8158286,8159947..8160406,8160481..8160691,8161625..8162469,8162546..8162747,8162815..8163889,8165973..8166152); ID=FBpp0298283; name=CG1632-PB; parent=FBgn0030027,FBtr0307282; dbxref=REFSEQ:NP_001245577,GB_protein:AFH07291,FlyBase:FBpp0298283,FlyBase_Annotation_IDs:CG1632-PB; MD5=10d4c851aa2388a1622d30b0bc51d59d; length=1056; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG1632 (CG1632, FBgn0030027). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8147264..8166502. It has the cytological map location 7E1. Based on sequence similarity, it is predicted to have molecular function</span>: low-density lipoprotein receptor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 16 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1056 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA]
    Molecular Function: low-density lipoprotein receptor activity [ISS]
    [NOT]serine-type endopeptidase activity [IEA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDIYYCSNS QMKKSRDADK SSATLSATNT NANAVNLSAA DKKNNNNNCS NRNKEKSMQA  60
   61 NGKNWKGIVQ SNPNPSGGVG TTAQPPKVFH NTRCTRHHKP HHSHGNGSAA SAVGGAAGLA 120
  121 NGPPMEATQQ RERERERDRD RERERERDRE RDREREREHQ LHMHQHNHGL RRKSESVLST 180
  181 DSDIRFTRRK LGDGQKCGCA VIAGFLIALL VAGIFVYVGY TYFRPEPLPD RVFRGRFMVL 240
  241 NDKWSMELAN QNSMRFQHKA RDYRERINLT LRRSDLREAY EGSEILALDG SEDNNNIVVH 300
  301 FNMIFDPYAG LVSSGDLLAL FHEEMTQPPQ QRRHFANMTV DVASLSIKET TGLIEEPIMS 360
  361 SSPLGGHDET TEPVVTTTPA PPRRCSPLEL SYCRQVGYNI TTYPNLLGHA SYEQLAEDVI 420
  421 VFRELVDGEC HREAYDFVCR LLQPPCDTHG SDLQPTPGQI CREYCESFMA GCGGRLPQRF 480
  481 RQFFDCERFP ESTGTQSCHQ KPHCVSDMQS NVQSPRLCDG YADCPDLSDE RSCAFCSPNA 540
  541 LYCGRGRACV PRKARCDGKA DCPDGADEKD CLSIAPLAAD LLQPEPLVPY LSRFHSAGYA 600
  601 VFSEKGVVGK LCAEGLEGDA KLVVRQTVSE SLCKSLGYES VEIFDVQNDT ERLNDYVRVL 660
  661 DPHAPEISFI RTHCPRRQVL YVGCGELRCG VQSALFNAKQ HLSLPKMSAP GDWPWLVALF 720
  721 REDIHVCDGT LITQDWVLTT EGCFQGQPRA TWMAIVGAVR LSAKAPWTQR RRIIGMIKSP 780
  781 VEGSTAALVR LETPVSYSDH VRPICLPDAL QRRLLQQPPA QRRSHVPVAE RLEGQLVSQQ 840
  841 RSRLSQENQQ FFLIPSQEQQ DSSTENQGDE DQDEQEDHFG GESAASYMPK AEALHQELDG 900
  901 YPLPDHAPQV NYYSSSSTVT SSSTAARIAT KAPILAAVPA AQEQIWTNCN TLGWSRQRDH 960
  961 LQRVQLKMGD MAPCENVSIA TVNSMCMEAT YQKYDCTQEE YSGAPVQCLI PGTNQWALIG1020
 1021 VSSWRIACGP TGVERPRMYD KIASNAAWIR ETISAI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] FFAS03 0.961 crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution
    2 View Details [219..379] PSI-BLAST 10.522879 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains
    3 View Details [380..496] PSI-BLAST 38.0 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
    4 View Details [497..1056] PSI-BLAST 42.0 No description for 2f83A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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