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Protein Overview: fs(1)h-PB

General Information:
Name(s) found: fs(1)h-PB / FBpp0071074 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene female sterile (1) homeotic is referred to in FlyBase by the symbol Dmel\fs(1)h (CG2252, FBgn0004656). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7933976..7955469. It has the cytological map location 7D3-7D5. It is reported to have molecular function</span>: protein kinase activity; DNA binding. It is reported to be involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter. 46 alleles are reported. The phenotypes of these alleles are annotated with: embryonic head; egg; metathoracic segment; mouth hooks; hypostomal sclerite. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2038 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of transcription from RNA polymerase II promoter [NAS]
    Molecular Function: DNA binding [NAS]
    protein kinase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSEPPPRY EPPVEPVNGI VQPPVIPPAE RPGRNTNQLQ YLIKTVMKVI WKHHFSWPFQ  60
   61 QPVDAKKLNL PDYHKIIKQP MDMGTIKKRL ENNYYWSAKE TIQDFNTMFN NCYVYNKPGE 120
  121 DVVVMAQTLE KVFLQKIESM PKEELELEPV TAKGGKKKQR APATPKSSSG GAGASTGSGT 180
  181 SSAAVTSGPG SGSTKVSVAA SSAQQSGLQG ATGAGGGSSS TPGTQPGSGA GGAIAARPVS 240
  241 AMGGTVSSTA GGAPSIPPIS TMPPHTVPGS TNTTTTAMAG GVGGPGAAGA NPNAAALMAS 300
  301 LLNAGQTGAY PGAPGQTAVN SSSLLDGSTA AVAAAAAAAA AAAAAAGGAA GAAGGAGTIP 360
  361 AVAVNAANAV QAYVNAGVSV GVDAVIPPQQ PAKIKKGVKR KADTTTPTAN AFESPYTQMD 420
  421 SKSAKIATRR ESNRQDLTFQ GSGYNMSPLG VSGVPGLGGL VAGGVAGVAV AKNKEKLSDA 480
  481 LKSCNEILKE LFSKKHSGYA WPFYKPVDAE MLGLHDYHDI IKKPMDLGTV KRKMDNREYK 540
  541 SAPEFAADVR LIFTNCYKYN PPDHDVVAMG RKLQDVFEMR YANIPDEPVA NAAHHHGHGH 600
  601 GHGHGHGHGH GHGHGHGHGH GYGGSSSLKH DASDSSSEDS SDTENESNSD EERSARLKML 660
  661 ESKLLGLQEE IRKLSEEASA KKKAKKKLKE KKKSIGGGSG SGSASHHCHA TGGGANAGGA 720
  721 GGPGSGGHGS VSVPGGVGSL GPGGAGGANL NALLGGSLVG HGGAAVAGGV PNVGALHSQV 780
  781 HDVAMAFSQM AGGGAAAGAG FGAGVTAAGA SSGGKAGTLA GALAAGAAAG AGGTTAGSGS 840
  841 SKGAKSKGGR GAKGSGAGGV GASNNAAAGN AAGGAAGAAA GAGSVGGVGG AGAAGGGNAS 900
  901 KRAKGSSSAG AGGGVGGANA SAGGAGARGS SKKKPSQVMN FDSEEEDTAK PMSYDEKRQL 960
  961 SLDINKLPGD KLGRVVHIIQ NREPSLRDSN PDEIEIDFET LKPSTLRELE SYVASCLRKK1020
 1021 THKKPSGKSK DEQMAEKKQE LEKRLQDVTG QLGASKKTAK KDESASSKVE AVQPANPVSS1080
 1081 SSSSSDSSSS SSSDSSSSDS SDSEAGDGDE RPPRKKKSRD SNGSNVNNPS INVVMGGNLP1140
 1141 SGALSPTTML MGLDHVVNSN TPTSQMSNML GNANPLTAAA MLNNNNKTSL PGSNFGGAPA1200
 1201 PGNMMHAGAG VPVAGAAVSA STGQQHNKNG PNDLSKVQPG GPINAALPPH SFAGGTATVA1260
 1261 TSQSSGGIRI ASNLHKPSGL GGGDLGEHHA ALAAALTSGI NSTGTAGGGI NNNGGSNNNA1320
 1321 NPLGGSHGDA MVNASLASLA SGLKQIPQFD DPVEQSLASL EFSAGSTGKS GLTDNFLMQQ1380
 1381 HLMQPAGPQQ QQQQQQQQPF GHQQQQQQQQ QQQQQQQQHM DYVTELLSKG AENVGGMNGN1440
 1441 HLLNFNLDMA AAYQQKHPQQ QQQQAHNNGF NVADFGMAGF DGLNMTAASF LDLEPSLQQQ1500
 1501 QMQQMQLQQQ HHQQQQQQTH QQQQQHQQQH HQQQQQQQLT QQQLQQQQQQ QQQQQHLQQQ1560
 1561 QHQQQHHQAA NKLLIIPKPI ESMMPSPPDK QQLQQHQKVL PPQQSPSDMK LHPNAAAAAA1620
 1621 VASAQAKLVQ TFKANEQNLK NASSWSSLAS ANSPQSHTSS SSSSSKAKPA MDSFQQFRNK1680
 1681 AKERDRLKLL EAAEKEKKNQ KEAAEKEQQR KHHKSSSSSL TSAAVAQAAA IAAATAAAAV1740
 1741 TLGAAAAAAL ASSASNPSGG SSSGGAGSTS QQAITGDRDR DRDRERERER SGSGGGQSGN1800
 1801 GNNSSNSANS NGPGSAGSGG SGGGGGSGPA SAGGPNSGGG GTANSNSGGG GGGGGPALLN1860
 1861 AGSNSNSGVG SGGAASSNSN SSVGGIVGSG GPGSNSQGSS GGGGGGPASG GGMGSGAIDY1920
 1921 GQQVAVLTQV AANAQAQHVA AAVAAQAILA ASPLGAMESG RKSVHDAQPQ ISRVEDIKAS1980
 1981 PGGQGQSSPA QQSPQDRAAA KRAEQRRAEQ ERRRREALAG QIDMNMQSDL MAAFEETL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] PSI-BLAST 49.0 No description for 1x0jA was found.
    2 View Details [141..308] deduced N/A No confident structure predictions are available.
    3 View Details [309..448] deduced N/A No confident structure predictions are available.
    4 View Details [449..586] PSI-BLAST 52.69897 No description for 2ouoA was found.
    5 View Details [587..967] PSI-BLAST 28.30103 No description for 1y0fA was found.
    6 View Details [968..1067] PSI-BLAST 11.39794 No description for 2j7tA was found.
    7 View Details [1068..1240] MSA 1.379982 View MSA. No confident structure predictions are available.
    8 View Details [1241..1620] PSI-BLAST 15.154902 Heavy meromyosin subfragment
    9 View Details [1621..1739] FFAS03 1.04 human APP core domain
    10 View Details [1740..1822] deduced N/A No confident structure predictions are available.
    11 View Details [1823..2038] FFAS03 1.23 Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9
    Term Confidence Notes
  • binding
    		•  0.225375777463061 bayes_pls_golite062009
    10 No functions predicted.
    11 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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