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Protein Overview: l(1)G0255-PA

General Information:
Name(s) found: l(1)G0255-PA / FBpp0070914 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene lethal (1) G0255 is referred to in FlyBase by the symbol Dmel\l(1)G0255 (CG4094, FBgn0028336). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6572499..6575887. It has the cytological map location 6C5. Based on sequence similarity, it is predicted to have molecular function</span>: fumarate hydratase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: tricarboxylic acid cycle. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 495 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISS]
    mitochondrion [ISS]
    tricarboxylic acid cycle enzyme complex [IEA]
    Biological Process: tricarboxylic acid cycle [ISS]
    fumarate metabolic process [IEA]
    Molecular Function: fumarate hydratase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLPLLQRST LRGVQQMTKP WAAIGSLRLA SQEFRVESDT FGELKVPADK YYGAQTMRSQ  60
   61 INFPIGGATE RMPKPVVQAM GILKKAAAEV NKEFGLDSKV SEAISKAADD VISGKLYDDH 120
  121 FPLVIWQTGS GTQSNMNVNE VISNRAIELL GGKLGSKTPV HPNDHVNKSQ SSNDTFPTAI 180
  181 HISVALELNN NLKPAIKTLH DALRAKSEEF KDIIKIGRTH TMDAVPLTLG QEFSGYAQQL 240
  241 AYAQERIDAC LPRVYELALG GTAVGTGLNT RKGFAEKCAA KIAELTSLPF VTAPNKFEAL 300
  301 AARDAMVEVH GVLNTIAVSL MKIANDIRFL GSGPRCGLGE LSLPENEPGS SIMPGKVNPT 360
  361 QCESLTMLSA QVMGNQVAVT IGGSNGHFEL NVFKPLIVSN VLRSIRLLSD GSRTFTANCV 420
  421 NGIQANRENI AKIMNESLML VTALNPHIGY DKAAKIAKTA HKNGTTLKEE AINLGYLTEQ 480
  481 QFNDWVRPEQ MLGPK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..495] PSI-BLAST 156.0 RECOMBINANT YEAST FUMARASE


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle