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Protein Overview: Btd-PA

General Information:
Name(s) found: Btd-PA / FBpp0070843 [FlyBase]
Description(s) found:
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  • gi|7290682|gb|AAF46130.1| biotinidase [Drosophila melanogaster] [NCBI NR]
  • gi|24640061|ref|NP_572298.1| biotinidase [Drosophila melanogaster] [NCBI NR]
  • The gene Biotinidase is referred to in FlyBase by the symbol Dmel\Btd (CG3599, FBgn0029848). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6111513..6113327. It has the cytological map location 5E1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. There is experimental evidence that it is involved in the biological process</span>: response to heat. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG3599-PA translation from_gene[CG3599 CG3599 FBgn0029848] seq_release:3 mol_weight=61904 cds_boundaries:(X:5,957,859..5,959,670[-]) aa_length:553 transcript_info:[CG3599-RA seq_release:3] gene_info:[gene symbol:CG3599 FBgn0029848 gene_boundaries:(X:5 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W430) CG3599 protein [DrosMelano7227.FASTAC.txt]
  • (AE003436) CG3599 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG3599-PA [Drosophila melanogaster]gi|24640061|ref|NP_572298.1| CG3599-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(6111513..6113114,6113268..6113327); ID=FBpp0070843; name=Btd-PA; parent=FBgn0029848,FBtr0070878; dbxref=FlyBase:FBpp0070843,FlyBase_Annotation_IDs:CG3599-PA,GB_protein:AAF46130.1,REFSEQ:NP_572298,GB_protein:AAF46130; MD5=d06 [fly-100309-contam.fasta]
  • CG3599-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(6111513..6113114,6113268..6113327); ID=FBpp0070843; name=Btd-PA; parent=FBgn0029848,FBtr0070878; dbxref=FlyBase:FBpp0070843,FlyBase_Annotation_IDs:CG3599-PA,GB_protein:AAF46130.1,REFSEQ:NP_572298,GB_protein:AAF46130; MD5=d06538b4a04b2e83f57a234ffc7c4688; length=553; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(6111513..6113114,6113268..6113327); ID=FBpp0070843; name=Btd-PA; parent=FBgn0029848,FBtr0070878; dbxref=FlyBase:FBpp0070843,FlyBase_Annotation_IDs:CG3599-PA,GB_protein:AAF46130.1,REFSEQ:NP_572298,GB_protein:AAF46130; MD5=d06538b4a04b2e83f57a234ffc7c4688; length=553; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Biotinidase OS=Drosophila melanogaster GN=Btd PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:complement(6111513..6113114,6113268..6113327); ID=FBpp0070843; name=Btd-PA; parent=FBgn0029848,FBtr0070878; dbxref=FlyBase:FBpp0070843,FlyBase_Annotation_IDs:CG3599-PA,GB_protein:AAF46130.1,REFSEQ:NP_572298,GB_protein:AAF46130,FlyMine:FBpp0070843,modMine:FBpp0070843; MD5=d06538b4a04b2e83f57a234ffc7c4688; length=553; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:complement(join(6219235..6219294,6217480..6219081)); ID=FBpp0070843; name=Btd-PA; parent=FBgn0029848,FBtr0070878; dbxref=FlyBase:FBpp0070843,FlyBase_Annotation_IDs:CG3599-PA,GB_protein:AAF46130.1,REFSEQ:NP_572298,GB_protein:AAF46130,FlyMine:FBpp0070843,modMine:FBpp0070843; MD5=d06538b4a04b2e83f57a234ffc7c4688; length=553; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(join(6219235..6219294,6217480..6219081)); ID=FBpp0070843; name=Btnd-PA; parent=FBgn0029848,FBtr0070878; dbxref=FlyBase:FBpp0070843,FlyBase_Annotation_IDs:CG3599-PA,GB_protein:AAF46130.1,REFSEQ:NP_572298,GB_protein:AAF46130,FlyMine:FBpp0070843,modMine:FBpp0070843; MD5=d06538b4a04b2e83f57a234ffc7c4688; length=553; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Biotinidase OS=Drosophila melanogaster GN=Btnd PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0070843 type=protein; loc=X:complement(join(6219235..6219294,6217480..6219081)); ID=FBpp0070843; name=Btnd-PA; parent=FBgn0029848,FBtr0070878; dbxref=FlyBase:FBpp0070843,FlyBase_Annotation_IDs:CG3599-PA,GB_protein:AAF46130.1,REFSEQ:NP_572298,GB_protein:AAF46130,FlyMine:FBpp0070843,modMine:FBpp0070843; MD5=d06538b4a04b2e83f57a234ffc7c4688; length=553; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:complement(join(6219235..6219294,6217480..6219081)); ID=FBpp0070843; name=Btnd-PA; parent=FBgn0029848,FBtr0070878; dbxref=FlyBase:FBpp0070843,FlyBase_Annotation_IDs:CG3599-PA,GB_protein:AAF46130.1,REFSEQ:NP_572298,GB_protein:AAF46130,UniProt/TrEMBL:Q9W430,FlyMine:FBpp0070843,modMine:FBpp0070843; MD5=d06538b4a04b2e83f57a234ffc7c4688; length=553; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 553 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: response to heat [IMP]
    nitrogen compound metabolic process [IEA]
    Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSIQLSFLL LSVLFSSSHQ LSKPEDPTYT AAVVEHSQPV GDSPRARTTS ASESFQKIIR  60
   61 EVGDVDIIVF PEHILNSQAT ATFVPHESQN ITPCYQTDYE LFLIELSCSA RANHLYVVIN 120
  121 VVEKELCAHG AGSDTYNPCP SSGVRYFNTN VVFDRRGRIV SRYRKTHLWR HEYVSTSVLR 180
  181 SPDISIFRTD FGVTFGHFIC FDMLFYDPAM KLVKEHKITD IVYPTYWFSE LPFLGAVQLQ 240
  241 EGWAFGNDVN VLAADASNPD GRTSGSGIYA GRGGRLVAEI FEQPTTKLLI AEVPKREHGQ 300
  301 LAPTFTPIFE PQRKTQRLTG LATYRDNNVD IFESELLDDD FLSFERQLCH GSFCCTFSIE 360
  361 RKVTSAAENE LPSSGAKSYR YRIGVYWGNE TTVIGVDRTE QATCALFACT DVRLASCGYI 420
  421 YPENEEVINT HHFTKLSISG NFPAAPRGRR LIMPSSLNAL FLPVSVSDYE WIESPEAANN 480
  481 LDKTILVDLK LAKAQNDLLT FAIWANYYTD IPSTHNLDHM QPNGTQSNPS TSASSTVSAF 540
  541 WILCVLNCFI SVL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..387] PSI-BLAST 59.69897 NIT-FHIT fusion protein, C-terminal domain; NIT-FHIT fusion protein, N-terminal domain
    2 View Details [388..553] MSA 1.07498 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  2.77860354143005 bayes_pls_golite062009
  • catalytic activity
    		•  1.64442398754697 bayes_pls_golite062009
  • binding
    		•  1.34662244603439 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.472813950465394 bayes_pls_golite062009
  • protein binding
    		•  0.399526580105167 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle