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Protein Overview: CG4078-PA, FBpp0...

General Information:
Name(s) found: FBpp0304672 [FlyBase]
CG4078-PA / FBpp0070773 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=X:join(5641902..5642951,5643027..5643574,5643770..5644433,5644495..5644637,5644882..5645011,5645097..5645306,5645375..5645587); ID=FBpp0304672; name=CG4078-PB; parent=FBgn0029798,FBtr0332398; dbxref=REFSEQ:NP_001259262,GB_protein:AGB95108,FlyBase:FBpp0304672,FlyBase_Annotation_IDs:CG4078-PB; MD5=5cabe995b5d8c8815b1584141e5aa205; length=985; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG4078 (CG4078, FBgn0029798). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5641782..5645815. It has the cytological map location 5B6. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent DNA helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nucleotide-excision repair. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 985 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nucleotide-excision repair [ISS]
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [IEA]
    Molecular Function: DNA binding [IEA]
    ATP binding [IEA]
    ATP-dependent DNA helicase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPESLIAGIP VHFPFEPYPV QRAYMEKVIH CLRDGTNGVL ESPTGTGKTL SLLCSSLAWI  60
   61 RTRQSEHQKQ MVKMEKADFS GLGGGAPGGD LSELAKTMGR ANNWGVPKVI YASRTHSQLT 120
  121 QAMRELKRTA YANMRSVVLG SRDQLCIHPE VMREQGNSNK TNMCKLRVHS KTCSFQMRVE 180
  181 SRKDHPDLRG PTIMDIEDLV KVGQRLKICP YFASRELVPQ ADITFMPYNY LLDPKARKAN 240
  241 KIELGNTIVI LDEAHNIEKI CEESASVQIK SSDVAMAIED VTHIMQVFAS GESQDMAGDE 300
  301 PKDFTLDDLT LLKEMLLELE KAIDAIVVDN AVDGTTFPAS MMYELLGKAN FTYGNVATIV 360
  361 SLLDKLVQYL LVASQQMSIR KGGTFTLLSD LLTIVFANKE DVMSKVYASF KVHVLVEESK 420
  421 QGHGKQQGAK QQGGWLGKGT IAAATGLSKV AKIINFWCFN PGFGMEQLLN TQVRSVILTS 480
  481 GTLAPLKPLI AELAIPVAQH LENPHIVDQS QVYVKIIGTG PDRQQLISNY ANRDNPKYIS 540
  541 SLGQTILNVA RIVPDGLLVF FPSYPMLNKC VDAWQASGLW ADISCKKPIF LEPRSKDQFT 600
  601 STMEEFYQAI RDSKGAVFMA VCRGKVSEGL DFADRNGRAV IITGLPFPPL KDPKVILKRR 660
  661 YLEANRTREN QLLSGQEWYN LDATRAVNQA IGRVIRHRND YGAILLCDSR FKDASQVQQL 720
  721 SKWIRGHLGD RPQCSPFGPI VRELRQFFKN AEANMKLPDE RETDSPLETV CKTEDEPLAA 780
  781 IPKVKREPGS NATFKSANES AIKVEMANSI KTWTPADYAS AAGHKLGGAA PNAMDFMSRL 840
  841 DSNVSSIDFN CCTDSKSGSS GLVKIHKRER SSPTAPESSS QVTKKRYKLV ENIKVEPSSS 900
  901 QAKEAPEERA AFLRELRSLV TQDQFRRFGK ALLEYKNGTY ESFQALMAIL LDVLSAPKVR 960
  961 YMLVGMRKYL KNEHKDEFDR RVGNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..985] FFAS03 1.92 No description for 2p6rA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.31308081280876 bayes_pls_golite062009
  • hydrolase activity
    		•  1.00975156763579 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.898216592483255 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.888726953718698 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.888190447032536 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.887947956048007 bayes_pls_golite062009
  • binding
    		•  0.64910342483548 bayes_pls_golite062009
  • ATPase activity
    		•  0.372097653399309 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle