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Protein Overview: Mnt-PA, Mnt-PC, ...

General Information:
Name(s) found: Mnt-PE / FBpp0291036 [FlyBase]
Mnt-PA / FBpp0070554 [FlyBase]
Mnt-PC / FBpp0070553 [FlyBase]
Description(s) found:
Found 41 descriptions.
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  • The gene Mnt is referred to in FlyBase by the symbol Dmel\Mnt (CG13316, FBgn0023215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3565834..3594813. It has the cytological map location 3E4-3E5. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription; regulation of cell cycle; negative regulation of cell growth; phagocytosis, engulfment. 31 alleles are reported. The phenotypes of these alleles are annotated with: eye; adult head; ommatidium; wing hair. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
  • The gene Mnt is referred to in FlyBase by the symbol Dmel\Mnt (CG13316, FBgn0023215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3565834..3594813. It has the cytological map location 3E4-3E5. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription; regulation of cell cycle; negative regulation of cell growth; phagocytosis, engulfment. 31 alleles are reported. The phenotypes of these alleles are annotated with: eye; adult head; ommatidium; wing hair. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
  • The gene Mnt is referred to in FlyBase by the symbol Dmel\Mnt (CG13316, FBgn0023215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3565834..3594813. It has the cytological map location 3E4-3E5. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription; regulation of cell cycle; negative regulation of cell growth; phagocytosis, engulfment. 31 alleles are reported. The phenotypes of these alleles are annotated with: eye; adult head; ommatidium; wing hair. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 582 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC][IDA][ISS]
    Biological Process: phagocytosis, engulfment [IMP]
    negative regulation of cell growth [IMP]
    regulation of cell cycle [IMP]
    regulation of transcription [IEA][IMP][ISS]
    Molecular Function: DNA binding [ISS]
    transcription factor activity [ISS]
    protein binding [IPI]
    RNA polymerase II transcription factor activity [ISS]
    sequence-specific DNA binding [IDA]
    transcription repressor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGIGGIGVL LEAAQFLEQH EKLPQAGGGG GSALGVGVAL PQQQQQTVHC KSNSIINNNN  60
   61 SSQHNRNSSS SSNGIIATPP FTNGNGNGTV GVGNASAIFN VSVNANGNGL SNGHSSPRSQ 120
  121 LAAAATAHDY EYSAAGVANG HSEGRPHVSA ARDQQDHPQH QQHANHMQIQ QHYGYMRSNI 180
  181 GGVIYGLHKD SADSAASSAC GAGAGAAAVG MSIASSAPAA GSQLSAHHHT GHGGRRRTTS 240
  241 SNSNGAGTRE VHNKLEKERR AQLKECYDLL KKVLPMGDED RKKTSNLTIL DTAHKYVNSL 300
  301 SHEVCEQEAK IEKLAKQKIE LQKRLKQLSL RRESPPTDQQ IIPQADKAVC LATTATTAPP 360
  361 TAASGHNGTT ILFDAGNACA TGQLTTVINK TNGGATAAAS SKHNGNHTGG ATTTLTPAMG 420
  421 IMTIKNGNGS NGNMLAISPT GGHNHQLHQH HNGSPAGSPS GIGATTGATI TRGSPTPSTP 480
  481 SPSPSSSSSG VSLSTSFMGG SSSSSSSSSS SSSSSSSSSS SSPTQQQQII TPTATARSVG 540
  541 LKFHGGAGAA VPAGGGSVNG FHQADKDRNY TFLRLSAGTT AQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..231] deduced N/A No confident structure predictions are available.
    2 View Details [232..336] PSI-BLAST 16.69897 Myc prot-oncogene protein
    3 View Details [337..399] deduced N/A No confident structure predictions are available.
    4 View Details [400..582] FFAS03 1.19 Crystal structure of the Burkholderia glumae lipase-specific foldase in complex with its cognate lipase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.12507195426228 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.43204604575196 bayes_pls_golite062009
  • DNA binding
    		•  0.40884226851256 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.31759335140578 bayes_pls_golite062009
  • transcription factor activity
    		•  0.09721565916723 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle