YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: Parg-PA

General Information:
Name(s) found: Parg-PA / FBpp0070560 [FlyBase]
Description(s) found:
Found 17 descriptions.
SHOW ALL
  • The gene Poly(ADP-ribose) glycohydrolase is referred to in FlyBase by the symbol Dmel\Parg (CG2864, FBgn0023216). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3562754..3565602. It has the cytological map location 3E2. There is experimental evidence that it has the molecular function</span>: poly(ADP-ribose) glycohydrolase activity. There is experimental evidence that it is involved in the biological process</span>: response to heat; regulation of histone acetylation; maintenance of protein location in nucleus; chromatin silencing; regulation of RNA splicing; carbohydrate metabolic process; phagocytosis, engulfment. 10 alleles are reported. The phenotypes of these alleles are annotated with: nucleolus; dorsocentral bristle; mesothoracic leg; wing. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 768 amino acids

    Gene Ontology:
    Cellular Component: nucleoplasm [IDA]
    Biological Process: carbohydrate metabolic process [IMP]
    response to heat [IMP]
    phagocytosis, engulfment [IMP]
    regulation of RNA splicing [IMP]
    regulation of histone acetylation [IMP]
    chromatin silencing [IMP]
    maintenance of protein location in nucleus [IMP]
    Molecular Function: poly(ADP-ribose) glycohydrolase activity [IMP][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQEFRSHLIF PIFQKVYQST ANRRRASASV LTNRLGKALC LNCARMSKSP DGGISEIETE  60
   61 EEPENLANSL DDSWRGVSME AIHRNRQPFE LENLPPVTAG NLHRVMYQLP IRETPPRPYK 120
  121 SPGKWDSEHV RLPCAPESKY PRENPDGSTT IDFRWEMIER ALLQPIKTCE ELQAAIISYN 180
  181 TTYRDQWHFR ALHQLLDEEL DESETRVFFE DLLPRIIRLA LRLPDLIQSP VPLLKHHKNA 240
  241 SLSLSQQQIS CLLANAFLCT FPRRNTLKRK SEYSTFPDIN FNRLYQSTGP AVLEKLKCIM 300
  301 HYFRRVCPTE RDASNVPTGV VTFVRRSGLP EHLIDWSQSA APLGDVPLHV DAEGTIEDEG 360
  361 IGLLQVDFAN KYLGGGVLGH GCVQEEIRFV ICPELLVGKL FTECLRPFEA LVMLGAERYS 420
  421 NYTGYAGSFE WSGNFEDSTP RDSSGRRQTA IVAIDALHFA QSHHQYREDL MERELNKAYI 480
  481 GFVHWMVTPP PGVATGNWGC GAFGGDSYLK ALLQLMVCAQ LGRPLAYYTF GNVEFRDDFH 540
  541 EMWLLFRNDG TTVQQLWSIL RSYSRLIKEK SSKEPRENKA SKKKLYDFIK EELKKVRDVP 600
  601 GEGASAEAGS SRVAGLGEGK SETSAKSSPE LNKQPARPQI TITQQSTDLL PAQLSQDNSN 660
  661 SSEDQALLML SDDEEANAMM EAASLEAKSS VEISNSSTTS KTSSTATKSM GSGGRQLSLL 720
  721 EMLDTHYEKG SASKRPRKSP NCSKAEGSAK SRKEIDVTDK DEKDDIVD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..64] deduced N/A No confident structure predictions are available.
    2 View Details [65..167] MSA 2.037979 View MSA. No confident structure predictions are available.
    3 View Details [168..268] deduced N/A No confident structure predictions are available.
    4 View Details [269..414] MSA 1.073957 View MSA. No confident structure predictions are available.
    5 View Details [415..485] deduced N/A No confident structure predictions are available.
    6 View Details [486..596] MSA 11.082993 View MSA. No confident structure predictions are available.
    7 View Details [597..768] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle