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Protein Overview: FBpp0301281, FBp...

General Information:
Name(s) found: FBpp0304768 [FlyBase]
FBpp0301281 [FlyBase]
FBpp0301280 [FlyBase]
FBpp0301279 [FlyBase]
FBpp0301278 [FlyBase]
kirre-PA / FBpp0070535 [FlyBase]
kirre-PB / FBpp0070534 [FlyBase]
Description(s) found:
Found 62 descriptions.
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  • type=protein; loc=X:join(3023311..3024345,3024415..3024517,3024592..3024719,3024776..3025880,3025959..3026458); ID=FBpp0304768; name=kirre-PG; parent=FBgn0028369,FBtr0332492; dbxref=REFSEQ:NP_001259196,GB_protein:AGB95042,FlyBase:FBpp0304768,FlyBase_Annotation_IDs:CG3653-PG; MD5=4e9f8e63f7dd55e3fcbc14fa91527202; length=956; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:join(3023311..3024345,3024415..3024517,3024592..3024719,3024776..3025880,3025959..3026458); ID=FBpp0301281; name=kirre-PF; parent=FBgn0028369,FBtr0309501; dbxref=FlyBase:FBpp0301281,FlyBase_Annotation_IDs:CG3653-PF,REFSEQ:NP_001245508,GB_protein:AFH07222; MD5=4e9f8e63f7dd55e3fcbc14fa91527202; length=956; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:join(3023311..3024345,3024415..3024517,3024592..3024719,3024776..3025880,3025959..3026458); ID=FBpp0301280; name=kirre-PE; parent=FBgn0028369,FBtr0309500; dbxref=FlyBase:FBpp0301280,FlyBase_Annotation_IDs:CG3653-PE,REFSEQ:NP_001245507,GB_protein:AFH07221; MD5=4e9f8e63f7dd55e3fcbc14fa91527202; length=956; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:join(3023311..3024345,3024415..3024517,3024592..3024719,3024776..3025880,3025959..3026458); ID=FBpp0301279; name=kirre-PD; parent=FBgn0028369,FBtr0309499; dbxref=FlyBase:FBpp0301279,FlyBase_Annotation_IDs:CG3653-PD,REFSEQ:NP_001245506,GB_protein:AFH07220; MD5=4e9f8e63f7dd55e3fcbc14fa91527202; length=956; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:join(3023311..3024345,3024415..3024517,3024592..3024719,3024776..3025880,3025959..3026458); ID=FBpp0301278; name=kirre-PC; parent=FBgn0028369,FBtr0309498; dbxref=FlyBase:FBpp0301278,FlyBase_Annotation_IDs:CG3653-PC,REFSEQ:NP_001245505,GB_protein:AFH07219; MD5=4e9f8e63f7dd55e3fcbc14fa91527202; length=956; release=r5.56; species=Dmel; [FlyBase]
  • The gene kin of irre is referred to in FlyBase by the symbol Dmel\kirre (CG3653, FBgn0028369). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2862308..3026836. It has the cytological map location 3C3-3C7. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: myoblast fusion; homophilic cell adhesion; larval visceral muscle development; heterophilic cell adhesion; regulation of striated muscle tissue development; garland cell differentiation. 68 alleles are reported. The phenotypes of these alleles are annotated with: myoblast; larval garland cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene kin of irre is referred to in FlyBase by the symbol Dmel\kirre (CG3653, FBgn0028369). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2862308..3026836. It has the cytological map location 3C3-3C7. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: myoblast fusion; homophilic cell adhesion; larval visceral muscle development; heterophilic cell adhesion; regulation of striated muscle tissue development; garland cell differentiation. 68 alleles are reported. The phenotypes of these alleles are annotated with: myoblast; larval garland cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 956 amino acids

    Gene Ontology:
    Cellular Component: adherens junction [IDA]
    plasma membrane [IDA][NAS]
    cell surface [IDA]
    Biological Process: myoblast fusion [IMP][NAS][TAS]
    heterophilic cell-cell adhesion [IMP]
    homophilic cell adhesion [IMP]
    regulation of striated muscle tissue development [IGI][IMP]
    garland cell differentiation [IMP]
    larval visceral muscle development [IMP]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRMRSSRLL VLPLILVLIL TLLLQPIAVH AKSKKNKSSQ SSHHGDSSSS SSSSSSSSGS  60
   61 SSAAASSAND ESKPKGGDNG GQHFAMEPQD QTAVVGSRVT LPCRVMEKVG ALQWTKDDFG 120
  121 LGQHRNLSGF ERYSMVGSDE EGDFSLDIYP LMLDDDAKYQ CQVGPGPQGE QGIRSRFAKL 180
  181 TVLVPPEAPK ITQGDYLVTT EDREIELECV SQGGKPAAEI TWIDGLGNVL TKGIEYVKEP 240
  241 LADSRRITAR SILKLAPKKE HHNTTFTCQA QNTADRTYRS AKLLLEVKYA PKVIVSVVGG 300
  301 ALAGGKIPEG AEVILSCQAD ANPHELSYRW FINDELMTGD FTTKMIIHNV SRQYHDAIVK 360
  361 CEVVNAVGKS EQSKKLDISF GPVFRQRPVS VEADLGATVS MRCDVAGNPE PEIEWISENS 420
  421 DQVVGVAAEL KLKVSSETAG RYFCKAVVNG FPEIGAEATL YVKRAPIITS HKVQFGGVGG 480
  481 RVKIDCLAFS IPKAEHILWS FEGKIINMSS ADPDIYIFEE HHLPEGVRAA LIIRDSKATH 540
  541 FGKYNCTVMN SYGGDSLVIT LLREPGNIPV LLVVMGSMFC VAIILMIVMI IIVYRKRRSR 600
  601 KKPMPADVIP EASRGGDKLN ELKSELRSKA YDVEYSEAGG DGLAINLTQS PMPDVQMKGA 660
  661 TLGVPLAGPV KFDERFSGDF GGDRYNRQCH IKNLKNQQET AYKGSPQANG YAHYFEYALD 720
  721 YSPPGGEGAA VVVGSGGVGK LKNGGMNSAT LPHSAAATVN GGGAGNGGGA SLPRNQRHEI 780
  781 QQSQQSNGFL GQPLLQNGID SRFSAIYGNP YLRTNSSLLP PLPPPSTANP AATPAPPPYH 840
  841 AARHGHAHHA NGGLKHFVGG AVITTSPVGN VNINGGGGGG STPSGGGGVG VGVAAGGSVS 900
  901 GSSSNLTASS NTLAATPLAG GGVGNSGQCA QSPSGQFILS NNGKGHTQKG PLATHV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..652] PSI-BLAST 48.69897 Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data
    2 View Details [653..782] PSI-BLAST 23.69897 No description for 2nziA was found.
    3 View Details [783..956] PSI-BLAST 3.39794 The solution structure of the first fibronectin type III domain of human Neogenin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • receptor activity
    		•  3.28625508322269 bayes_pls_golite062009
  • cytokine binding
    		•  3.2860603878984 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.25570370343123 bayes_pls_golite062009
  • protein binding
    		•  3.24522318184038 bayes_pls_golite062009
  • growth factor binding
    		•  2.93401336059128 bayes_pls_golite062009
  • cytokine receptor activity
    		•  2.88339176908459 bayes_pls_golite062009
  • signal transducer activity
    		•  2.84396290475308 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.84396290475308 bayes_pls_golite062009
  • binding
    		•  2.69537882298808 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  2.32179186005318 bayes_pls_golite062009
  • axon guidance receptor activity
    		•  2.01367445237355 bayes_pls_golite062009
  • interleukin-2 binding
    		•  1.97207055102823 bayes_pls_golite062009
  • receptor binding
    		•  1.31676259534833 bayes_pls_golite062009
  • interleukin-6 receptor activity
    		•  1.09234260277228 bayes_pls_golite062009
  • interleukin-6 binding
    		•  1.09234260277228 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.99058387466784 bayes_pls_golite062009
  • interleukin-2 receptor activity
    		•  0.894667058714949 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.86564366658585 bayes_pls_golite062009
  • peptide hormone binding
    		•  0.748974198898009 bayes_pls_golite062009
  • heparin binding
    		•  0.7054081997714 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.68515307569834 bayes_pls_golite062009
  • sialic acid binding
    		•  0.678724159869891 bayes_pls_golite062009
  • ankyrin binding
    		•  0.56921114104552 bayes_pls_golite062009
  • identical protein binding
    		•  0.564711394496051 bayes_pls_golite062009
  • prolactin receptor activity
    		•  0.46231350624978 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.4326581122899 bayes_pls_golite062009
  • monosaccharide binding
    		•  0.356315624949755 bayes_pls_golite062009
  • cell surface binding
    		•  0.269982591934356 bayes_pls_golite062009
  • pattern binding
    		•  0.16768253393396 bayes_pls_golite062009
  • protein homodimerization activity
    		•  0.116391819218123 bayes_pls_golite062009
  • integrin binding
    		•  0.0873424694168858 bayes_pls_golite062009
  • interleukin-7 binding
    		•  0.0658245746738992 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0209293958870509 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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