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View Structure Prediction Details

Protein: FBpp0301281, FBp...
Organism: Drosophila melanogaster
Length: 956 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0301281, FBp....

Description E-value Query
Range		 Subject
Range
gi|47214649 - gi|47214649|emb|CAG05169.1| unnamed protein product [Tetraodon nigroviridis]
 428.0 [0..1] [946..192]

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Predicted Domain #1
Region A:
Residues: [1-652] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRMRSSRLL VLPLILVLIL TLLLQPIAVH AKSKKNKSSQ SSHHGDSSSS SSSSSSSSGS  60
   61 SSAAASSAND ESKPKGGDNG GQHFAMEPQD QTAVVGSRVT LPCRVMEKVG ALQWTKDDFG 120
  121 LGQHRNLSGF ERYSMVGSDE EGDFSLDIYP LMLDDDAKYQ CQVGPGPQGE QGIRSRFAKL 180
  181 TVLVPPEAPK ITQGDYLVTT EDREIELECV SQGGKPAAEI TWIDGLGNVL TKGIEYVKEP 240
  241 LADSRRITAR SILKLAPKKE HHNTTFTCQA QNTADRTYRS AKLLLEVKYA PKVIVSVVGG 300
  301 ALAGGKIPEG AEVILSCQAD ANPHELSYRW FINDELMTGD FTTKMIIHNV SRQYHDAIVK 360
  361 CEVVNAVGKS EQSKKLDISF GPVFRQRPVS VEADLGATVS MRCDVAGNPE PEIEWISENS 420
  421 DQVVGVAAEL KLKVSSETAG RYFCKAVVNG FPEIGAEATL YVKRAPIITS HKVQFGGVGG 480
  481 RVKIDCLAFS IPKAEHILWS FEGKIINMSS ADPDIYIFEE HHLPEGVRAA LIIRDSKATH 540
  541 FGKYNCTVMN SYGGDSLVIT LLREPGNIPV LLVVMGSMFC VAIILMIVMI IIVYRKRRSR 600
  601 KKPMPADVIP EASRGGDKLN ELKSELRSKA YDVEYSEAGG DGLAINLTQS PM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.69897
Match: 1e07A
Description: Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [653-782] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDVQMKGATL GVPLAGPVKF DERFSGDFGG DRYNRQCHIK NLKNQQETAY KGSPQANGYA  60
   61 HYFEYALDYS PPGGEGAAVV VGSGGVGKLK NGGMNSATLP HSAAATVNGG GAGNGGGASL 120
  121 PRNQRHEIQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.69897
Match: 2nziA
Description: No description for 2nziA was found.

Predicted Domain #3
Region A:
Residues: [783-956] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQQSNGFLGQ PLLQNGIDSR FSAIYGNPYL RTNSSLLPPL PPPSTANPAA TPAPPPYHAA  60
   61 RHGHAHHANG GLKHFVGGAV ITTSPVGNVN INGGGGGGST PSGGGGVGVG VAAGGSVSGS 120
  121 SSNLTASSNT LAATPLAGGG VGNSGQCAQS PSGQFILSNN GKGHTQKGPL ATHV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.39794
Match: 1x5fA
Description: The solution structure of the first fibronectin type III domain of human Neogenin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 3.28625508322269 bayes_pls_golite062009
cytokine binding 3.2860603878984 bayes_pls_golite062009
transmembrane receptor activity 3.25570370343123 bayes_pls_golite062009
protein binding 3.24522318184038 bayes_pls_golite062009
growth factor binding 2.93401336059128 bayes_pls_golite062009
cytokine receptor activity 2.88339176908459 bayes_pls_golite062009
signal transducer activity 2.84396290475308 bayes_pls_golite062009
molecular transducer activity 2.84396290475308 bayes_pls_golite062009
binding 2.69537882298808 bayes_pls_golite062009
cell adhesion molecule binding 2.32179186005318 bayes_pls_golite062009
axon guidance receptor activity 2.01367445237355 bayes_pls_golite062009
interleukin-2 binding 1.97207055102823 bayes_pls_golite062009
receptor binding 1.31676259534833 bayes_pls_golite062009
interleukin-6 receptor activity 1.09234260277228 bayes_pls_golite062009
interleukin-6 binding 1.09234260277228 bayes_pls_golite062009
glycosaminoglycan binding 0.99058387466784 bayes_pls_golite062009
interleukin-2 receptor activity 0.894667058714949 bayes_pls_golite062009
protein dimerization activity 0.86564366658585 bayes_pls_golite062009
peptide hormone binding 0.748974198898009 bayes_pls_golite062009
heparin binding 0.7054081997714 bayes_pls_golite062009
structural constituent of muscle 0.68515307569834 bayes_pls_golite062009
sialic acid binding 0.678724159869891 bayes_pls_golite062009
ankyrin binding 0.56921114104552 bayes_pls_golite062009
identical protein binding 0.564711394496051 bayes_pls_golite062009
prolactin receptor activity 0.46231350624978 bayes_pls_golite062009
polysaccharide binding 0.4326581122899 bayes_pls_golite062009
monosaccharide binding 0.356315624949755 bayes_pls_golite062009
cell surface binding 0.269982591934356 bayes_pls_golite062009
pattern binding 0.16768253393396 bayes_pls_golite062009
protein homodimerization activity 0.116391819218123 bayes_pls_golite062009
integrin binding 0.0873424694168858 bayes_pls_golite062009
interleukin-7 binding 0.0658245746738992 bayes_pls_golite062009
transcription activator activity 0.0209293958870509 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle