Protein Overview: FBpp0309090, egh...

General Information:
Name(s) found:	FBpp0309090 [FlyBase] egh-PB / FBpp0070424 [FlyBase] egh-PC / FBpp0070423 [FlyBase]
Description(s) found: Found 49 descriptions. SHOW ALL	type=protein; loc=X:join(2490248..2491048,2491360..2491932); ID=FBpp0309090; name=egh-PD; parent=FBgn0001404,FBtr0340091; dbxref=FlyBase:FBpp0309090,FlyBase_Annotation_IDs:CG9659-PD; MD5=727cf7cf53571ad63155c138cab23511; length=457; release=r5.56; species=Dmel; [FlyBase] The gene egghead is referred to in FlyBase by the symbol Dmel\egh (CG9659, FBgn0001404). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2482534..2492638. It has the cytological map location 3A6. There is experimental evidence that it has the molecular function</span>: beta-1,4-mannosyltransferase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: reproductive process in a multicellular organism; anatomical structure development; multicellular organism reproduction; ovarian follicle cell development; cellular component movement; organ morphogenesis; gamete generation; transport; regulation of response to stimulus; cell fate commitment; establishment or maintenance of polarity of follicular epithelium. 60 alleles are reported. The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: adult segment; organ system; nervous system; multi-cell-component structure; female germline cyst; peripheral nervous system; adult brain; egg; embryonic nervous system; external compound sense organ. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene egghead is referred to in FlyBase by the symbol Dmel\egh (CG9659, FBgn0001404). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2482534..2492638. It has the cytological map location 3A6. There is experimental evidence that it has the molecular function</span>: beta-1,4-mannosyltransferase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: reproductive process in a multicellular organism; anatomical structure development; multicellular organism reproduction; ovarian follicle cell development; cellular component movement; organ morphogenesis; gamete generation; transport; regulation of response to stimulus; cell fate commitment; establishment or maintenance of polarity of follicular epithelium. 60 alleles are reported. The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: adult segment; organ system; nervous system; multi-cell-component structure; female germline cyst; peripheral nervous system; adult brain; egg; embryonic nervous system; external compound sense organ. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	457 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [NAS]
Biological Process:	germ cell development [IMP] germarium-derived egg chamber formation [IMP] negative regulation of female receptivity, post-mating [IMP] axon guidance [IMP] border follicle cell migration [IMP] ovarian follicle cell-cell adhesion [IMP] maintenance of polarity of follicular epithelium [IMP] optic lobe placode formation [IMP] regulation of oviposition [IMP] oogenesis [TAS] ovarian follicle cell development [IMP][TAS] cell fate commitment [IMP] morphogenesis of follicular epithelium [IMP] dsRNA transport [IMP] oocyte localization during germarium-derived egg chamber formation [IMP] oocyte microtubule cytoskeleton organization [IMP]
Molecular Function:	beta-1,4-mannosyltransferase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSTTKHLLH CTLLITVIVT FEVFSGGIKI DENSFTLVDP WTEYGQLATV LLYLLRFLTL  60
   61 LTLPQVLFNF CGLVFYNAFP EKVVLKGSPL LAPFICIRVV TRGDFPDLVK TNVLRNMNTC 120
  121 LDTGLENFLI EVVTDKAVNL SQHRRIREIV VPKEYKTRTG ALFKSRALQY CLEDNVNVLN 180
  181 DSDWIVHLDE ETLLTENSVR GIINFVLDGK HPFGQGLITY ANENVVNWLT TLADSFRVSD 240
  241 DMGKLRLQFK LFHKPLFSWK GSYVVTQVSA ERSVSFDNGI DGSVAEDCFF AMRAFSQGYT 300
  301 FNFIEGEMYE KSPFTLLDFL QQRKRWLQGI LLVVHSKMIP FKHKLLLGIS VYSWVTMPLS 360
  361 TSNIIFAALY PIPCPNLVDF VCAFIAAINI YMYVFGVIKS FSLYRFGLFR FLACVLGAVC 420
  421 TIPVNVVIEN VAVIWGLVGK KHKFYVVQKD VRVLETV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..361]	PSI-BLAST	21.30103	The Crystal Structure of UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase-T1
2	View Details	[362..457]	deduced	N/A	No confident structure predictions are available.

Protein Overview: FBpp0309090, egh...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: