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Protein Overview: Rbcn-3B-PA, FBpp...

General Information:
Name(s) found: FBpp0310568 [FlyBase]
Rbcn-3B-PA / FBpp0070303 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • type=protein; loc=X:1804790..1809367; ID=FBpp0310568; name=Rbcn-3B-PB; parent=FBgn0023510,FBtr0344155; dbxref=FlyBase:FBpp0310568,FlyBase_Annotation_IDs:CG17766-PB; MD5=ec4957032c31d8c0a4d7b297050394f7; length=1525; release=r5.56; species=Dmel; [FlyBase]
  • The gene Rabconnectin-3B is referred to in FlyBase by the symbol Dmel\Rbcn-3B (CG17766, FBgn0023510). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1802957..1810207. It has the cytological map location 2B15. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of Notch signaling pathway; vacuolar acidification. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1525 amino acids

    Gene Ontology:
    Cellular Component: heterotrimeric G-protein complex [ISS]
    Biological Process: G-protein coupled receptor protein signaling pathway [ISS]
    regulation of Notch signaling pathway [IMP]
    vacuolar acidification [IMP]
    Molecular Function: GTPase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSTNLVVPV VLWGPTAPTH CISSVFLSDD QFTLVTGCYD GQICLWQVEP TTLKMSPRCL  60
   61 LVGHSAPVLC LVRASLLPEN NFLVSSSENG EMCTWDLTDG KCMEAVKLPQ VHTQIQSYHT 120
  121 ANSEDVRLFC IGYYAEIMVM DPFSLEVIYV LSSKVKPDWI SAIHVLRPMR RKDDVVLAIT 180
  181 TTGTVKVWTL TGNENKHAEP IYENESKEIR CLNAITMNCC AQNQRTVLLV CTKYWQIYDA 240
  241 GDFTVLCSVI APARERWQGG DFITSDRVML WTDEGKGYLY KLPANCIPDN KEFHSKSVVR 300
  301 DAPYLYYVLQ HAGDKVLSCP PAMKLLQGAG GQHNLLRGDS EGYISVWNVP EVPLDNISIL 360
  361 QAKQMPPRPL KPHVCTSLVE AWSIMDPPPV GILDQLSRIT ESPVKLTSSI YLPQQSRLVI 420
  421 GREDGSIVIV PATQTVMMQL LVGIKQNFSD WPSHQILYGH RGRVNCLLCP SMIHSRYEKS 480
  481 HLLSGGIDFA VCLWDLYSGS LLHRFCVHAG EITQLLVPPE SCSPRILKCI CSVASDHSVT 540
  541 LVSLQERKCV TLASRHLFPV VTIKWRPLDD FLIVGCSDGS VYVWQMETGH LDRVLHGMLA 600
  601 EEVLSACDEQ AEDGGSGGGG GSNGASASEM GMANPAVHFF RGLKSRNMNA IRHATQRGIT 660
  661 QLQQLQGHNQ GNFDFLMKHR SNPLVIQGLR TNPKDAESHI LFFDIEGLIF ELHSEEYAQM 720
  721 TPATLESLGV HLQNPKDGKS MHLDASKKIG DFFNKVKNKA VDVEKILKDK DKHGLVQKFK 780
  781 EKTEIVEKKV QAKVESLQKA VEPHEEQQDL KSKIASKMEV THVMEVAQLL LSLLHSWGLD 840
  841 PHLDKMCETR LGLLRPIVPI SYGVLSKAGY MSLLLPTWQN NYAIPPGIQL PSSSKKRPLP 900
  901 EELQRLEHLT AVFTSRLHWE LSTTLTTNHI LALVAMSNTL LSMSAASFLP DSEKHKKLQR 960
  961 LAQRTDSTLS NEEEREELMA HHISQIKHAW SLLATHHCFL LPDKIEALEP KKFKRPQVEM1020
 1021 MVKRWQHHCI EIREAAQQIL LGELTRMGKK GRKQLVESWA QYLPLYTHTE PIVGAQQQLA1080
 1081 LISQPASGGA GSGSGGNGGV GVGVSGGGGA GSGSGPGGSV PGGDAHQDED YEEEEEEIIR1140
 1141 KPSSLSELKR KQTTAVILLG VIGAEFGQDI SQESPNHRGS ISMATGANLT SGVAGGERRK1200
 1201 SSVVEGFGIA NNLARLTSMA LAHLLYAPPS PKLPQYTPLR RAAIDLLGRG FTVWEPYLDV1260
 1261 SKVLLGLLEI SCEGKAVPNL NYKLPLTPQA DACRTARHAL RLIATARPAA FITTMAREVA1320
 1321 RYNTMQQNAQ SINTPLTQSV LHKAKGEILQ CVEMLIDKMQ SEIAGLLVEV MDIALHCVDG1380
 1381 NELKNRGLAE LCPAICKFNQ ISHCAQTRRI AVGANSGNLA IYELRQNKCQ MIPAHTHPIT1440
 1441 SLAFSPDGKY LVSYSCAENR LSFWQTSTGM FGLGQSQTRC TKGYSTAPIP DVSRLNPMRL1500
 1501 AKLVWINNRT VTLMLADGSE TRFNV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..310] PSI-BLAST 20.0 No description for 2pm9A was found.
    2 View Details [311..387] PSI-BLAST 72.69897 PAF-AH Holoenzyme: Lis1/Alfa2
    3 View Details [388..745] PSI-BLAST 66.0 No description for 2ovpB was found.
    4 View Details [746..808] PSI-BLAST 4.221849 No description for 2ojhA was found.
    5 View Details [809..918] deduced N/A No confident structure predictions are available.
    6 View Details [919..1137] deduced N/A No confident structure predictions are available.
    7 View Details [1138..1198] deduced N/A No confident structure predictions are available.
    8 View Details [1199..1291] deduced N/A No confident structure predictions are available.
    9 View Details [1292..1525] PSI-BLAST 6.09691 Tricorn protease; Tricorn protease N-terminal domain; Tricorn protease domain 2


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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