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Protein Overview: MED22-PA

General Information:
Name(s) found: MED22-PA / FBpp0070160 [FlyBase]
Description(s) found:
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  • gi|74947368|sp|Q9V439.1|MED22_DROME RecName: Full=Mediator of RNA polymerase II transcription subunit 22; AltName: Full=Mediator complex subunit 22; AltName: Full=dMED24 [NCBI NR]
  • gi|7290099|gb|AAF45564.1| mediator complex subunit 22 [Drosophila melanogaster] [NCBI NR]
  • gi|18543195|ref|NP_569870.1| mediator complex subunit 22 [Drosophila melanogaster] [NCBI NR]
  • gi|17945359|gb|AAL48735.1| RE16720p [Drosophila melanogaster] [NCBI NR]
  • gi|10190799|emb|CAB65873.1| EG:BACR7A4.6 [Drosophila melanogaster] [NCBI NR]
  • Mediator of RNA polymerase II transcription subunit 22 OS=Drosophila melanogaster GN=MED22 PE=1 SV=1 [Swiss-Prot]
  • The gene Mediator complex subunit 22 is referred to in FlyBase by the symbol Dmel\MED22 (CG3034, FBgn0040339). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:822170..822893. It has the cytological map location 1D2. It is reported to have molecular function</span>: RNA polymerase II transcription mediator activity. It is reported to be involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG3034-PA translation from_gene[CG3034 Med24 FBgn0040339] seq_release:3 mol_weight=16594 cds_boundaries:(X:685,653..686,201[+]) aa_length:143 transcript_info:[CG3034-RA seq_release:3] gene_info:[gene symbol:Med24 synonyms:[CG18830] FBgn0040339 gene_bo [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V439) CG3034 protein (RE16720p) [DrosMelano7227.FASTAC.txt]
  • (AE003419) EG:BACR7A4.6 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG3034-PA [Drosophila melanogaster]gi|17945359|gb|AAL48735.1| RE16720p [Drosophila melanogaster]gi|18543195|ref|NP_569870.1| CG3034-PA [Drosophila melanogaster]gi|10190799|emb|CAB65873.1| EG:BACR7A4.6 [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(822249..822360,822417..822518,822583..822800); ID=FBpp0070160; name=MED22-PA; parent=FBgn0040339,FBtr0070165; dbxref=FlyBase:FBpp0070160,FlyBase_Annotation_IDs:CG3034-PA,GB_protein:AAF45564.1,REFSEQ:NP_569870,GB_protein:AAF45564; [fly-100309-contam.fasta]
  • RE16720p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG3034-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Mediator complex subunit 22 CG3034-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • EG:BACR7A4.6 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(822249..822360,822417..822518,822583..822800); ID=FBpp0070160; name=MED22-PA; parent=FBgn0040339,FBtr0070165; dbxref=FlyBase:FBpp0070160,FlyBase_Annotation_IDs:CG3034-PA,GB_protein:AAF45564.1,REFSEQ:NP_569870,GB_protein:AAF45564; MD5=ade417e9cba20561ed0159704a4a2ca2; length=143; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(822249..822360,822417..822518,822583..822800); ID=FBpp0070160; name=MED22-PA; parent=FBgn0040339,FBtr0070165; dbxref=FlyBase:FBpp0070160,FlyBase_Annotation_IDs:CG3034-PA,GB_protein:AAF45564.1,REFSEQ:NP_569870,GB_protein:AAF45564; MD5=ade417e9cba20561ed0159704a4a2ca2; length=143; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=X:join(822249..822360,822417..822518,822583..822800); ID=FBpp0070160; name=MED22-PA; parent=FBgn0040339,FBtr0070165; dbxref=FlyBase:FBpp0070160,FlyBase_Annotation_IDs:CG3034-PA,GB_protein:AAF45564.1,REFSEQ:NP_569870,GB_protein:AAF45564,FlyMine:FBpp0070160,modMine:FBpp0070160; MD5=ade417e9cba20561ed0159704a4a2ca2; length=143; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(928216..928327,928384..928485,928550..928767); ID=FBpp0070160; name=MED22-PA; parent=FBgn0040339,FBtr0070165; dbxref=FlyBase:FBpp0070160,FlyBase_Annotation_IDs:CG3034-PA,GB_protein:AAF45564.1,REFSEQ:NP_569870,GB_protein:AAF45564,FlyMine:FBpp0070160,modMine:FBpp0070160; MD5=ade417e9cba20561ed0159704a4a2ca2; length=143; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(928216..928327,928384..928485,928550..928767); ID=FBpp0070160; name=MED22-PA; parent=FBgn0040339,FBtr0070165; dbxref=FlyBase:FBpp0070160,FlyBase_Annotation_IDs:CG3034-PA,GB_protein:AAF45564.1,REFSEQ:NP_569870,GB_protein:AAF45564,FlyMine:FBpp0070160,modMine:FBpp0070160; MD5=ade417e9cba20561ed0159704a4a2ca2; length=143; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0070160 type=protein; loc=X:join(928216..928327,928384..928485,928550..928767); ID=FBpp0070160; name=MED22-PA; parent=FBgn0040339,FBtr0070165; dbxref=FlyBase:FBpp0070160,FlyBase_Annotation_IDs:CG3034-PA,GB_protein:AAF45564.1,REFSEQ:NP_569870,GB_protein:AAF45564,FlyMine:FBpp0070160,modMine:FBpp0070160; MD5=ade417e9cba20561ed0159704a4a2ca2; length=143; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(928216..928327,928384..928485,928550..928767); ID=FBpp0070160; name=MED22-PA; parent=FBgn0040339,FBtr0070165; dbxref=FlyBase:FBpp0070160,FlyBase_Annotation_IDs:CG3034-PA,GB_protein:AAF45564.1,REFSEQ:NP_569870,GB_protein:AAF45564,UniProt/Swiss-Prot:Q9V439,FlyMine:FBpp0070160,modMine:FBpp0070160; MD5=ade417e9cba20561ed0159704a4a2ca2; length=143; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 143 amino acids

    Gene Ontology:
    Cellular Component: mediator complex [IDA]
    Biological Process: regulation of transcription from RNA polymerase II promoter [IC][IEA]
    Molecular Function: RNA polymerase II transcription mediator activity [IC][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASGSRTTIL PQSKEALLKS YNARLKDDVR SMLENFEEIL KLARRESHSQ ISKTTQCEQD  60
   61 ALEMQVRAAN MVRAGESLMK LVADLKQYLI LNDFHSVNEA ITNNSQLFRN TQSECDKKLM 120
  121 KLRDEMAMDL YDLEEEYYTS IFK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..143] Pfam 90.0 No description for PF06179.3 was found. Confident ab initio structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

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