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Protein Overview: CG5254-PA

General Information:
Name(s) found: CG5254-PA / FBpp0070129 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5254 (CG5254, FBgn0040383). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:650221..652752. It has the cytological map location 1C4. Based on sequence similarity, it is predicted to have molecular function</span>: transmembrane transporter activity; tricarboxylate secondary active transmembrane transporter activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 306 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial envelope [ISS]
    mitochondrial inner membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    autophagic cell death [IEP]
    salivary gland cell autophagic cell death [IEP]
    Molecular Function: transmembrane transporter activity [ISS]
    tricarboxylate secondary active transmembrane transporter activity [ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGQQHDISH AKRAAFQVLA GGSAGFLEVC IMQPLDVVKT RIQIQATPAP NAAALGEVHY  60
   61 NGVFDCFAKM YRHEGISSYW KGIMPPILAE TPKRAIKFLV FEQTKPLFQF GSPTPTPLTF 120
  121 SLAGLTAGTL EAIAVNPFEV VKVAQQADRQ KKMLSTFAVA KGIIQQDGLG FSGLNKGITA 180
  181 TMGRNGVFNM VYFGFYHSVK NVVPEYKESH LEFLRKVTIG FLAGTLACFV NIPFDVAKSR 240
  241 IQGPQPVPGQ IKYRGTLSSM GIVYREEGFR ALYKGLVPKI MRLGPGGAIL LLVFEYSYDY 300
  301 LLHNYS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..306] PSI-BLAST 72.221849 structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.30

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle