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Protein Overview: Suv4-20-PA, FBpp...

General Information:
Name(s) found: FBpp0300875 [FlyBase]
Suv4-20-PA / FBpp0070146 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=X:complement(544083..547271,547403..548116); ID=FBpp0300875; name=Hmt4-20-PB; parent=FBgn0025639,FBtr0308652; dbxref=FlyBase:FBpp0300875,FlyBase_Annotation_IDs:CG13363-PB,REFSEQ:NP_001245453,GB_protein:AFH07169; MD5=7f1596fcfa0adc0d1c1b32a6856c72cb; length=1300; release=r5.56; species=Dmel; [FlyBase]
  • The gene Suv4-20 is referred to in FlyBase by the symbol Dmel\Suv4-20 (CG13363, FBgn0025639). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:542522..550075. It has the cytological map location 1B13-1B14. There is experimental evidence that it has the molecular function</span>: histone methyltransferase activity (H4-K20 specific). There is experimental evidence that it is involved in the biological process</span>: histone methylation; histone H4-K20 dimethylation; regulation of gene expression, epigenetic; histone H4-K20 trimethylation. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1300 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: histone H4-K20 dimethylation [IMP]
    histone methylation [IDA][IMP]
    histone H4-K20 trimethylation [IMP]
    regulation of gene expression, epigenetic [IMP]
    Molecular Function: histone methyltransferase activity (H4-K20 specific) [IDA][IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVGSNHTRR GETGSRFTNS SSSSSTSGGP TASASSTTSV TSSLATNSTS TSTAAALLSS  60
   61 MSHKSHGPPP SAPPSAHHQT NQQHHQVAHS QPHATHYQQT NQHPSHHHQS HQSSNGSGGG 120
  121 SAGSGSGSGS VVSGLNGCNG SAVSRLSQST GMSPRELSEN DDLATSLILD PHLGFQTHKM 180
  181 NIRFRPLKVD TQQLKAIVDD FIHTQNYDIA IQRIYEGPWI PRHLKNKNKI ATKRLHDHIV 240
  241 RYLRVFDKDS GFAIEACYRY TLEEQRGAKI SSTKRWSKND KIECLVGCIA ELTEAEEAAL 300
  301 LHSGKNDFSV MYSCRKNCAQ LWLGPAAYIN HDCRANCKFL ATGRDTACVK VLRDIEVGEE 360
  361 ITCFYGEDFF GDSNRYCECE TCERRGTGAF AGKDDGLMLG LSMGLGLASS GPGNNGGYRL 420
  421 RETDNRINRI KSRANSTNST SNSNSNTNDS TGPSETSSTN GLVASGGAGG ATGAAMLPTP 480
  481 SQQSTGGKEA TAAVSLLEKK LPNVVVSPLT MKELRQKGMT KYDAEMIMAN AAYQQQHHHQ 540
  541 HHFHHHHHHH HHHHNHGQHA STGAEATAAV QQMAAMQKPG VGGTGAAGNA GATTVSSVAA 600
  601 GAGSEVNGGR STSLRKSMRV NSTSSSISTA SADEVIAPVV AASISLPSKA PVVLMPRCKP 660
  661 AQMAIAALHQ SQQRQLRRSE RQKEKLTDGE SSDTSSEQQK KEQKQQDHQL PQKMFSLAEE 720
  721 PQPEKSEEKQ QEQQKRVTRN SAGRVGLVAR LATAHNNNIA TTTNSSSSSN KATTITNCNN 780
  781 HNSNNSSRIN HNSNLSSRLS VKSRKPAPSE ASSIPSSTSS ENQQQQATRR SCSPTPAYKK 840
  841 NLLASFDPDP PSTQGIKEQL KDESVTYSPV KQKRSRRAAA LAAAQSIHCE ALGGFPTGST 900
  901 GSQRKRAQAG EPTTSCSSTT ISNVEPLLKT PERRLKLTLR MKRSPILDEV IELGTSLSNG 960
  961 GAGRGAPGSH REGTAGEGSV RSALNLTGSS SNGIEYEILR MEGISEHGND DDEDEEEDDE1020
 1021 EPAAEEEEEP PPKEELQLVN KKQRKKQRSR SRSSQRRSPA PSSVYGTPQK KRLRLIFGNE1080
 1081 SHTIDIPPAA AEGSGSGLDD LNSSGGGGDE SFNASYASST SLTVNTSSSS TSSSSGVGGA1140
 1141 TSTSAEPVDS STVGPPIAAQ SPSSTTSSSF QSACTSTTNS NSYFPNGKQR AAGEDSYAMH1200
 1201 YYQLGKFAGT PSPGQGQAIV SSSSGSSGGG GSGAGFLSMP KHTFGTCALL APTSFACLQN1260
 1261 QPQISQQKTS SGGGAGVVPT STSTGAVTSH HHTNNHHGQK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] deduced N/A No confident structure predictions are available.
    2 View Details [187..389] PSI-BLAST 39.69897 No description for 2igqA was found.
    3 View Details [390..455] deduced N/A No confident structure predictions are available.
    4 View Details [456..621] deduced N/A No confident structure predictions are available.
    5 View Details [622..775] deduced N/A No confident structure predictions are available.
    6 View Details [776..1018] deduced N/A No confident structure predictions are available.
    7 View Details [1019..1059] deduced N/A No confident structure predictions are available.
    8 View Details [1060..1187] deduced N/A No confident structure predictions are available.
    9 View Details [1188..1300] MSA 4.251997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.69

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle