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Protein Overview: FBpp0311392, cal...

General Information:
Name(s) found: FBpp0311392 [FlyBase]
cals-PB / FBpp0088272 [FlyBase]
cals-PA / FBpp0088271 [FlyBase]
Description(s) found:
Found 44 descriptions.
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  • type=protein; loc=4:complement(1136453..1136520,1136582..1136705,1136952..1137082,1137141..1137224,1137286..1137840,1138477..1138531,1138594..1139643,1140563..1140673,1140732..1141232,1141285..1141427,1142085..1142199); ID=FBpp0311392; name=Cals-PD; parent=FBgn0039928,FBtr0345193; dbxref=FlyBase:FBpp0311392,FlyBase_Annotation_IDs:CG11059-PD; MD5=95e4b0992c6ed271b93c68fe1b6f8f6f; length=978; release=r5.56; species=Dmel; [FlyBase]
  • The gene calsyntenin-1 is referred to in FlyBase by the symbol Dmel\cals (CG11059, FBgn0039928). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:1135804..1144024. It has the cytological map location 102F8. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic transmission; calcium-dependent cell-cell adhesion. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene calsyntenin-1 is referred to in FlyBase by the symbol Dmel\cals (CG11059, FBgn0039928). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:1135804..1144024. It has the cytological map location 102F8. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic transmission; calcium-dependent cell-cell adhesion. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 978 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [ISS]
    postsynaptic membrane [ISS]
    extracellular region [ISS]
    Biological Process: calcium-dependent cell-cell adhesion [ISS]
    synaptic transmission [ISS][NAS]
    homophilic cell adhesion [IEA]
    Molecular Function: calcium ion binding [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTFHKTFGYG CIVLICFELL FAGVETSSEN DDEYLTQKEI ILEKSYHGLI RENETLVEIT  60
   61 PLIKVNEEKI CNFHILKKPY HEIPFKIELV NNLGILKARR TLNCENRKSY HFEICAIYCD 120
  121 GTPSNTANVH ITVIDVNEYA PTFLEPSYVI EVDEGRLYNE ILRVEASDKD CTPLFGDVCK 180
  181 YEILNNDEPF SIDNEGSIKN TEPLSHKASH NHILSVVAYD CAMKESAPIM VSIKVRRVCE 240
  241 TKFVGMPERI DYTSGSTESL QLFPNARLDL CDISCKNEED LRIHSSIALK TKHISFGCDR 300
  301 DISNCTSGQK VKDLLPHGAE WTKELSYDEG LEPIFHFDGS TGVVVPATVI DHYDFSSQPF 360
  361 SILTLFRHNS QVEINKHVKE HIVCSADDHK MNRHHMALFV RNCRLIFLLR KNFNEGDLNI 420
  421 FSPAEWRWKI PEVCDNEWHH YVLNVEDSSK VDLFIDGVRF ENSIENRHSN PEVIDDWPLH 480
  481 AAHGVNTSLA IGACYQSLEN RLKHGFNGDI SEVKVSLNSV LTAEDIKCGT TCAEHLLAPK 540
  541 PLQSNNEKSY SDNSQIKENI EMNEIYISAK NKHDIEQFMR KVQYINTKQK PTVGRRNIEV 600
  601 LTTLNCKNES SLRLPPIETY IMVNEPIAPL GIDIDVVSAS LETSDLTPPS YSPKIAISGT 660
  661 SNKLVSYQEI KLGVHILEKT CIDSVSKNNG KLEEKNHIDS CSVVVFPSLN PDHEDIKIDG 720
  721 DESLSSSMDI KTNINKDGVE MIGKDTISNY INVLRSLVYS NKKPAYYLNR VFKLSCAQQS 780
  781 SQYKSGEYTL TLTVLHPKQT LFKSTNVLPS SLSKVNFIGN TDNETSFHRN SGSVNGNDNN 840
  841 QPTESKVYSY SLLHTNNVQE PKSHIHSFIH KAEGSHVTML IILVSVFLAV LLCGVSIARL 900
  901 KNNQKYIEHH QPCPKISDDG LIWDDSALTI TINPMQADVT SDASSESENS ESEDEEALKD 960
  961 GFTHINQLEW DNSNIFQQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..507] PSI-BLAST 60.69897 W-shaped trans interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography
    2 View Details [508..659] MSA 1.280988 View MSA. No confident structure predictions are available.
    3 View Details [660..889] deduced N/A No confident structure predictions are available.
    4 View Details [890..978] MSA 2.026995 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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