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Protein Overview: mod-PA, FBpp0301951

General Information:
Name(s) found: FBpp0301951 [FlyBase]
mod-PA / FBpp0085233 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • type=protein; loc=3R:join(27878457..27878699,27878968..27879277,27879345..27880079,27880146..27880486); ID=FBpp0301951; name=mod-PC; parent=FBgn0002780,FBtr0310268; dbxref=FlyBase:FBpp0301951,FlyBase_Annotation_IDs:CG2050-PC,REFSEQ:NP_001247401,GB_protein:AFH06718; MD5=0475f421fccdda40bdf90693f539fb01; length=542; release=r5.56; species=Dmel; [FlyBase]
  • The gene modulo is referred to in FlyBase by the symbol Dmel\mod (CG2050, FBgn0002780). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27877794..27880696. It has the cytological map location 100E3. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; DNA binding. There is experimental evidence that it is involved in the biological process</span>: spermatid development; cell proliferation. 23 alleles are reported. The phenotypes of these alleles are annotated with: embryonic labial segment; embryonic/larval posterior spiracle; embryonic maxillary segment; macrochaeta; somatic muscle; embryonic mandibular segment; larval midgut. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 542 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    cytoplasm [IDA]
    protein complex [IPI]
    nucleolus [IDA]
    Biological Process: cell proliferation [IMP]
    spermatid development [IMP]
    Molecular Function: nucleotide binding [IEA]
    DNA binding [IDA][NAS]
    protein binding [IPI][NAS]
    mRNA binding [ISS][NAS]
    sequence-specific DNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQKKAVTVK GKKATNGEEK PLAKRVTKST KVQEEETVVP QSPSKKSRKQ PVKEVPQFSE  60
   61 EDESDVEEQN DEQPGDDSDF ETEEAAGLID DEAEEDEEYN SDDEEDDDDD ELEPGEVSKS 120
  121 EGADEVDESD DDEEAPVEKP VSKKSEKANS EKSEENRGIP KVKVGKIPLG TPKNQIVFVT 180
  181 NLPNEYLHKD LVALFAKFGR LSALQRFTNL NGNKSVLIAF DTSTGAEAVL QAKPKALTLG 240
  241 DNVLSVSQPR NKEENNERTV VVGLIGPNIT KDDLKTFFEK VAPVEAVTIS SNRLMPRAFV 300
  301 RLASVDDIPK ALKLHSTELF SRFITVRRIS QESISRTSEL TLVVENVGKH ESYSSDALEK 360
  361 IFKKFGDVEE IDVVCSKAVL AFVTFKQSDA ATKALAQLDG KTVNKFEWKL HRFERSTSGR 420
  421 AILVTNLTSD ATEADLRKVF NDSGEIESII MLGQKAVVKF KDDEGFCKSF LANESIVNNA 480
  481 PIFIEPNSLL KHRLLKKRLA IGQTRAPRKF QKDTKPNFGK KPFNKRPAQE NGGKSFVKRA 540
  541 RF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..167] MSA 6.356996 View MSA. No confident structure predictions are available.
    2 View Details [168..248] PSI-BLAST 38.522879 Poly(A)-binding protein
    3 View Details [249..542] PSI-BLAST 19.69897 No description for 2ghpA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  3.2072391084044 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.34356093608328 bayes_pls_golite062009
  • mRNA binding
    		•  2.19775829895338 bayes_pls_golite062009
  • RNA binding
    		•  1.69266495798651 bayes_pls_golite062009
  • protein binding
    		•  1.14508556628804 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  3.2072391084044 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.34356093608328 bayes_pls_golite062009
  • mRNA binding
    		•  2.19775829895338 bayes_pls_golite062009
  • RNA binding
    		•  1.69266495798651 bayes_pls_golite062009
  • protein binding
    		•  1.14508556628804 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle