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Protein Overview: pygo-PA

General Information:
Name(s) found: pygo-PA / FBpp0085167 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene pygopus is referred to in FlyBase by the symbol Dmel\pygo (CG11518, FBgn0043900). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27401557..27406412. It has the cytological map location 100C6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: wing disc morphogenesis; positive regulation of Wnt receptor signaling pathway; delamination; imaginal disc-derived wing expansion; eye-antennal disc development; dendrite morphogenesis; embryonic pattern specification; transcription, DNA-dependent; Wnt receptor signaling pathway; Wnt receptor signaling pathway, calcium modulating pathway. 36 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; adult segment; cuticle; peripheral nervous system; adult mesothoracic segment; nervous system; embryonic neuron; imaginal precursor; adult cuticle; external compound sense organ. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 815 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    Biological Process: delamination [IMP]
    wing disc morphogenesis [IMP]
    transcription, DNA-dependent [IMP]
    embryonic pattern specification [IMP]
    Wnt receptor signaling pathway, calcium modulating pathway [IMP]
    imaginal disc-derived wing expansion [IMP]
    Wnt receptor signaling pathway [IGI][IMP][IPI][NAS]
    positive regulation of Wnt receptor signaling pathway [IGI][IMP]
    eye-antennal disc development [IMP]
    dendrite morphogenesis [IMP]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPI]
    transcription activator activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTHNLGMAPY RLPGPAGGLC PPDFKPPPPT DIISAPSNPK KRRKTSSAAN SAAAVAAAAA  60
   61 AAAAANSMQQ QQAPPTPQDL LPPPPMGGFG DTIIASNPFD DSPQVSAMSS SAAAAMAAMN 120
  121 QMGGGPGGGH FGGGGPGGHP HWEDRMGMGG GPPPPPHMHP HMHPHHPGGP MGHPHGPHPH 180
  181 MGGPPPMRGM SPMHPHQMGP GPGVGLPPHM NHGRPGGPGG PGGPVPMGSP MGGIAGMGGM 240
  241 SPMGGMGGPS ISPHHMGMGG LSPMGGGPNG PNPRAMQGSP MGGPGQNSPM NSLPMGSPMG 300
  301 NPIGSPLGPP SGPGPGNPGN TGGPQQQQQQ PPQPPMNNGQ MGPPPLHSPL GNGPTGHGSH 360
  361 MPGGPIPGPG PGPGGLVGPG GISPAHGNNP GGSGNNMLGG NPGGGNSNNN GSNTSNASNN 420
  421 NQNPHLSPAA GRLGVPTSMQ SNGPSVSSVA SSSVPSPATP TLTPTSTATS MSTSVPTSSP 480
  481 APPAMSPHHS LNSAGPSPGM PNSGPSPLQS PAGPNGPNNN NSNNNNGPMM GQMIPNAVPM 540
  541 QHQQHMGGGP PGHGPGPMPG MGMNQMLPPQ QPSHLGPPHP NMMNHPHHPH HHPGGPPPHM 600
  601 MGGPGMHGGP AGMPPHMGGG PNPHMMGGPH GNAGPHMGHG HMGGVPGPGP GPGGMNGPPH 660
  661 PHMSPHHGHP HHHHNPMGGP GPNMFGGGGG GPMGPGGPMG NMGPMGGGPM GGPMGVGPKP 720
  721 MTMGGGKMYP PGQPMVFNPQ NPNAPPIYPC GMCHKEVNDN DEAVFCESGC NFFFHRTCVG 780
  781 LTEAAFQMLN KEVFAEWCCD KCVSSKHIPM VKFKC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..815] PSI-BLAST 98.09691 No description for 1y0fB was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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