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Protein Overview: CG11334-PA, CG11...

General Information:
Name(s) found: FBpp0306623 [FlyBase]
CG11334-PB / FBpp0085170 [FlyBase]
CG11334-PA / FBpp0085169 [FlyBase]
Description(s) found:
Found 39 descriptions.
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  • type=protein; loc=3R:complement(27285734..27286063,27286122..27286285,27286352..27286584,27286643..27286878,27287536..27287667); ID=FBpp0306623; name=CG11334-PC; parent=FBgn0039849,FBtr0334556; dbxref=FlyBase:FBpp0306623,FlyBase_Annotation_IDs:CG11334-PC,REFSEQ:NP_001263144,GB_protein:AGB96523; MD5=23c8daa3db6f03c7f5321f699cb0ceaa; length=364; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG11334 (CG11334, FBgn0039849). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27285544..27288730. It has the cytological map location 100C4. Based on sequence similarity, it is predicted to have molecular function</span>: translation regulator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translation. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG11334 (CG11334, FBgn0039849). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27285544..27288730. It has the cytological map location 100C4. Based on sequence similarity, it is predicted to have molecular function</span>: translation regulator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translation. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 364 amino acids

    Gene Ontology:
    Cellular Component: eukaryotic translation initiation factor 2B complex [ISS]
    Biological Process: translation [ISS]
    Molecular Function: translation regulator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLQSIKYSR GSLEILDQLL LPGQSKYVVV RGVEDGWKVI NKMQVRGAPA IAIVGCLSLA  60
   61 VEINPEDFEN KKSLRQEIEG KLNYLVSARP TAVNMKIAAD ELITLANELY KDEAIDVTQM 120
  121 KHRFLDATEA MLKKDIADNR AIGANGAQAI LQGVAKAGKA PAGSTGSVRV LTHCNTGSLA 180
  181 TAGYGTALGV VRQLAELGKL EHVYCTETRP YNQGARLTAY ELVHEKFPAT LVLDSMVAAL 240
  241 LRAKNVAAVV VGADRVASNG DTANKIGTYQ IAVVAKHHDV PFYVAAPLTS IDLAIPGGDH 300
  301 IIIEERPDRE MTHVGEHRIA APGINCWNPA FDVTPASLIT GIITERGVFK PAELKEAITK 360
  361 LLES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..364] PSI-BLAST 118.0 X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  10.1099993541596 bayes_pls_golite062009
  • translation regulator activity
    		•  5.74669335554405 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.56128901279222 bayes_pls_golite062009
  • transferase activity, transferring sulfur-containing groups
    		•  1.40526340076289 bayes_pls_golite062009
  • catalytic activity
    		•  1.31732715713197 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.09424756417577 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.987801998446038 bayes_pls_golite062009
  • binding
    		•  0.946249883212717 bayes_pls_golite062009
  • DNA binding
    		•  0.730721872216867 bayes_pls_golite062009
  • deaminase activity
    		•  0.518630450774121 bayes_pls_golite062009
  • S-methyl-5-thioribose-1-phosphate isomerase activity
    		•  0.511292518421556 bayes_pls_golite062009
  • transcription factor activity
    		•  0.195177143221873 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle