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Protein Overview: CG11340-PA

General Information:
Name(s) found: CG11340-PA / FBpp0085128 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG11340 (CG11340, FBgn0039840). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27128572..27130804. It has the cytological map location 100C1. Based on sequence similarity, it is predicted to have molecular function</span>: extracellular-glycine-gated chloride channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ion transport. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 526 amino acids

    Gene Ontology:
    Cellular Component: glycine-gated chloride channel complex [ISS]
    postsynaptic membrane [IEA]
    Biological Process: ion transport [IEA]
    Molecular Function: extracellular-glycine-gated chloride channel activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTLGIFVLI SYLGLSSAAG VHLGDLQQNL AANGSVVVSP LNTTDAFSVS INLSQSTVNN  60
   61 CPSLKNAESM ALMELLTRLT APCRYDRMVP PVVHNKDGEE VPMDIYARFY IYVMKNLDSS 120
  121 DLQFTVQGLL QLRYLDPRLA FSSYLPNRRQ PIMGESELKK MLWVPHIFLT NEQASTVLGT 180
  181 SAKDELTSIY PNGTVLTSTR LQATLYCWMN FQKFPFDEQK CKTTLESWMY NTTLVQLHWE 240
  241 TDNPVSFDKQ LQLTEYNLIG SLYNESIRVS NESYMSHGSL EGNYSIISFT VLLTREVGYY 300
  301 VIDYFLPSIM IVTISWVSFW LQADQTPART TLGCTTLLSF ITLSLSQENN LMKVSYVTMS 360
  361 EVWFLVCTIF IFGSLVEFAF VNTIWRRNND LQLKKRTTKY IVKSTFVPHL KKHRRHGYRR 420
  421 TDSTMSTMST TSMDKTCGPN NTVITIETPI IIGGSLSRED SAISLDEQDE TSTSESSDSS 480
  481 KEKPAQTFAT MTPKEVSLWI DRKMRFVFPL SFIVFNALFW TLVYCL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..421] PSI-BLAST 70.0 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    2 View Details [422..526] PSI-BLAST 33.154902 Acetylcholine receptor protein, beta chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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