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Protein Overview: zwilch-PA

General Information:
Name(s) found: zwilch-PA / FBpp0085138 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene zwilch is referred to in FlyBase by the symbol Dmel\zwilch (CG18729, FBgn0061476). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27036685..27039072. It has the cytological map location 100B6. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitotic cell cycle spindle assembly checkpoint; mitosis. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 641 amino acids

    Gene Ontology:
    Cellular Component: kinetochore [IDA]
    Biological Process: mitotic cell cycle spindle assembly checkpoint [IMP]
    mitosis [IMP]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASANLANV YAELMRRCGE SYTITYGAPP TYLVSMVGAA EAGKKIVLVF KEDRNGAVAR  60
   61 LRTTPTRAAP KKEGSADLDL TGSPLKDDCL VDAIADLSID LQLDHSNPWK LEEEYQRGIP 120
  121 VDKARSIVCS EFLQLAEGLG SVWFLCDGSD LGQTQLLQYE FNPTHFSRGI LSYQGVRPAY 180
  181 LVTSQALVRH HGKTPDETLI ENSYQVNPHM RLRCSWTSSA ALPLLVNLND CDVALNHTFR 240
  241 VGDCGPLTQD FMNQLRILVY IREDIVSYHT DVKQGVSRDP TYRCGSGIDM DELRESINQT 300
  301 MTDVSGLIGR YSISNAEFDI EDVVQRAKVR QLTDLTDKLW ELLKCCHSYK DLKIAFSMLF 360
  361 QCAARCNIVN TPTNKNRLAK IITELANRRL AMPCLSGAEP LELLLEIGLE KLYKDYEFIY 420
  421 TESKMCSTNL LKDDSSGASM DDGSPQNLPQ LRKSLHNAVR GDPTPGAGMR KTLLHHHGAV 480
  481 NSRSTKYAGS DDDAGFKNSH FDEHESTERI SKLFQIHCTL EHLLMMHIHL NLANVYNDVC 540
  541 SELLKKPPKL VESIDDQLSD VMDIRLSAHY VRDHLDGKDP YSRHITMRSH NKFRELKTTF 600
  601 YFNSENICPP NLAQCFQCDD KEMVKERTYH SWIYHKIRSL K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] deduced N/A No confident structure predictions are available.
    2 View Details [117..192] MSA 1.018988 View MSA. No confident structure predictions are available.
    3 View Details [193..309] deduced N/A No confident structure predictions are available.
    4 View Details [310..463] MSA 1.016952 View MSA. No confident structure predictions are available.
    5 View Details [464..641] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle