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Protein Overview: spdo-PA

General Information:
Name(s) found: spdo-PA / FBpp0085013 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene sanpodo is referred to in FlyBase by the symbol Dmel\spdo (CG31020, FBgn0260440). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26302411..26304311. It has the cytological map location 99F6. There is experimental evidence that it has the molecular function</span>: Notch binding; protein binding. There is experimental evidence that it is involved in the biological process</span>: heart morphogenesis; sensory organ development; Notch signaling pathway; asymmetric cell division. 19 alleles are reported. The phenotypes of these alleles are annotated with 45 unique terms, many of which group under: peripheral nervous system; hypodermal muscle of larval abdomen; embryonic nervous system; organ system; nervous system; embryonic neuron; abdominal oblique muscle; larval abdominal segment 5; multi-cell-component structure; commissure. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 565 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    integral to membrane [ISS]
    cytoplasmic vesicle [IDA]
    plasma membrane [IDA]
    cortical cytoskeleton [IDA]
    Biological Process: heart morphogenesis [IMP]
    Notch signaling pathway [IGI][IPI]
    peripheral nervous system development [NAS][TAS]
    asymmetric cell division [IMP]
    sensory organ development [IMP]
    Molecular Function: protein binding [IPI]
    Notch binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQHNYTNPA FCQNSEYYPV PSGNSSRVES IYNRSLQMNF GAAPPRATRD PREGPLRMQR  60
   61 SMSTRSVTRK QHQQQQQQQH QQQIHQQHLA QQQQHQPQSS SGRYALVPLE ELNSSRASRY 120
  121 AIVPGQAAQR LARSQDNLDR YGSRHGLHEE EEPHSFHEEP HQETQFASLP PILNLPPKPR 180
  181 NINNNTNANQ TQIKHAFSSD FGSKTFLIVD KNSNQRYQMV PTAEDEELVD ENQEIIQMHN 240
  241 GRAHRYAVVP TDADDDDLAE EQEQQETCLS NMELSRQYAA RTSTPQQKNA AAATRALHEL 300
  301 LTTPRKMQPP PRLAHSTPRN AAHHEQLQLE RRLEIYKSQQ IYQSQQVGAV VGVPPTLPLR 360
  361 QNRLSPQRLH YETVKPLPMQ IADRSMAVIS PRVQEQGQEQ EREQDMSSIQ GKGKKNSSYP 420
  421 QKMANATITL AVVSLMLVLG STMNAGLIIY MIAHLGKSFY LQFSLVASFS GMGLGFLGFK 480
  481 SRHCEWLPNR SYSSGYILVT VFCLFKSCGL LVILVVDPFP GFPVHDVTTG VILGLSTFTM 540
  541 FFIGLGVLGS LWCHRPPPDN RVNVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..252] MSA 2.21599 View MSA. No confident structure predictions are available.
    2 View Details [253..434] MSA 4.222997 View MSA. No confident structure predictions are available.
    3 View Details [435..565] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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