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Protein Overview: sas-6-PA

General Information:
Name(s) found: sas-6-PA / FBpp0084912 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene spindle assembly abnormal 6 is referred to in FlyBase by the symbol Dmel\sas-6 (CG15524, FBgn0039731). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25821079..25822760. It has the cytological map location 99D1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization; centriole replication; centrosome duplication. 8 alleles are reported. The phenotypes of these alleles are annotated with: centriole; centrosome. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 472 amino acids

    Gene Ontology:
    Cellular Component: centrosome [ISS]
    centriole [IDA]
    Biological Process: centrosome duplication [IMP][ISS]
    centriole replication [IMP]
    mitotic spindle organization [IMP]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWPPGSEDSY SAKMDYGKSV VNILPSVEML VNFNGEMTRS SKRSCLLYAE RVDFKELLQL  60
   61 RLTEKSDQRR MYITTVDSAS FQDLKQDQSL NVSFSGFIDN VVRMLKDCQS GKLELHLTTR 120
  121 DQNLSSGREV HDYYLQFVEI RSFKNLVHLS LPCRSAPLNT VLFYINSMLE ASHKKQYILE 180
  181 QSMQQMQAEI NAQRAHAERL TTENTNIREA LAENTRILEE KHAAEVHQYQ EKLSKINEQR 240
  241 SNELERNRRA ISGFQAQLDK ASLEKAELKS AQEQAEKRCQ TLSEELSCCK ARVCTLKEQN 300
  301 DKLHGDVANI RKHERKLEYK IEDLKQHTVE LQEHIQKGNK EKANIAAELE AEKKILHTKR 360
  361 QALEMASEEI SKANQIIVKQ SQELLNLKKT IAWRTEVALQ QEKAVQAKES LLSLRENELR 420
  421 EARITIEKLR EEIPQQLQSM RNFAQGLEQK YSKQILILKE RLAIPTGKEN RR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..89] deduced N/A No confident structure predictions are available.
    2 View Details [90..400] PSI-BLAST 28.045757 Heavy meromyosin subfragment
    3 View Details [401..472] PSI-BLAST 7.0 No description for 2i1jA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle