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Protein Overview: ligatin-PA

General Information:
Name(s) found: ligatin-PA / FBpp0084779 [FlyBase]
Description(s) found:
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  • gi|7677626|gb|AAF67203.1|AF260235_1 LIGATIN [Drosophila melanogaster] [NCBI NR]
  • gi|23172544|gb|AAN14162.1| ligatin [Drosophila melanogaster] [NCBI NR]
  • gi|17137750|ref|NP_477481.1| ligatin [Drosophila melanogaster] [NCBI NR]
  • gi|15291717|gb|AAK93127.1| LD24540p [Drosophila melanogaster] [NCBI NR]
  • The gene ligatin is referred to in FlyBase by the symbol Dmel\ligatin (CG31426, FBgn0041588). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:24975618..24977512. It has the cytological map location 98F13. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translational initiation. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG31426-PA translation from_gene[CG31426 ligatin FBgn0041588] seq_release:3 mol_weight=61932 cds_boundaries:(3R:24,965,031..24,966,777[-]) aa_length:563 transcript_info:[CG31426-RA seq_release:3] gene_info:[gene symbol:ligatin FBgn0041588 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9NG60) Ligatin (LD24540P) (CG31426-PA) [DrosMelano7227.FASTAC.txt]
  • CG31426-PA [Drosophila melanogaster]gi|15291717|gb|AAK93127.1| LD24540p [Drosophila melanogaster]gi|17137750|ref|NP_477481.1| CG31426-PA [Drosophila melanogaster]gi|7677626|gb|AAF67203.1| LIGATIN [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(24975662..24976953,24977012..24977411); ID=FBpp0084779; name=ligatin-PA; parent=FBgn0041588,FBtr0085410; dbxref=FlyBase:FBpp0084779,FlyBase_Annotation_IDs:CG31426-PA,GB_protein:AAN14162.1,REFSEQ:NP_477481,GB_protein:AAN1416 [fly-100309-contam.fasta]
  • LD24540p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG31426-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LIGATIN [Drosophila melanogaster] [nr-271106-contam.fasta]
  • ligatin CG31426-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(24975662..24976953,24977012..24977411); ID=FBpp0084779; name=ligatin-PA; parent=FBgn0041588,FBtr0085410; dbxref=FlyBase:FBpp0084779,FlyBase_Annotation_IDs:CG31426-PA,GB_protein:AAN14162.1,REFSEQ:NP_477481,GB_protein:AAN14162; MD5=903977e146896db1346c55106d8bfd9a; length=563; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(24975662..24976953,24977012..24977411); ID=FBpp0084779; name=ligatin-PA; parent=FBgn0041588,FBtr0085410; dbxref=FlyBase:FBpp0084779,FlyBase_Annotation_IDs:CG31426-PA,GB_protein:AAN14162.1,REFSEQ:NP_477481,GB_protein:AAN14162; MD5=903977e146896db1346c55106d8bfd9a; length=563; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • LD24540p OS=Drosophila melanogaster GN=ligatin PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(24975662..24976953,24977012..24977411); ID=FBpp0084779; name=ligatin-PA; parent=FBgn0041588,FBtr0085410; dbxref=FlyBase:FBpp0084779,FlyBase_Annotation_IDs:CG31426-PA,GB_protein:AAN14162.1,REFSEQ:NP_477481,GB_protein:AAN14162,FlyMine:FBpp0084779,modMine:FBpp0084779; MD5=903977e146896db1346c55106d8bfd9a; length=563; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(29151290..29151689,29149940..29151231)); ID=FBpp0084779; name=ligatin-PA; parent=FBgn0041588,FBtr0085410; dbxref=FlyBase:FBpp0084779,FlyBase_Annotation_IDs:CG31426-PA,GB_protein:AAN14162.1,REFSEQ:NP_477481,GB_protein:AAN14162,FlyMine:FBpp0084779,modMine:FBpp0084779; MD5=903977e146896db1346c55106d8bfd9a; length=563; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(29151290..29151689,29149940..29151231)); ID=FBpp0084779; name=eIF2D-PA; parent=FBgn0041588,FBtr0085410; dbxref=FlyBase:FBpp0084779,FlyBase_Annotation_IDs:CG31426-PA,GB_protein:AAN14162.1,REFSEQ:NP_477481,GB_protein:AAN14162,FlyMine:FBpp0084779,modMine:FBpp0084779; MD5=903977e146896db1346c55106d8bfd9a; length=563; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • LD24540p OS=Drosophila melanogaster GN=eIF2D PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0084779 type=protein; loc=3R:complement(join(29151290..29151689,29149940..29151231)); ID=FBpp0084779; name=eIF2D-PA; parent=FBgn0041588,FBtr0085410; dbxref=FlyBase:FBpp0084779,FlyBase_Annotation_IDs:CG31426-PA,GB_protein:AAN14162.1,REFSEQ:NP_477481,GB_protein:AAN14162,FlyMine:FBpp0084779,modMine:FBpp0084779; MD5=903977e146896db1346c55106d8bfd9a; length=563; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(29151290..29151689,29149940..29151231)); ID=FBpp0084779; name=eIF2D-PA; parent=FBgn0041588,FBtr0085410; dbxref=FlyBase:FBpp0084779,FlyBase_Annotation_IDs:CG31426-PA,GB_protein:AAN14162.1,REFSEQ:NP_477481,GB_protein:AAN14162,UniProt/TrEMBL:Q9NG60,FlyMine:FBpp0084779,modMine:FBpp0084779; MD5=903977e146896db1346c55106d8bfd9a; length=563; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 563 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: translational initiation [ISS]
    Molecular Function: translation initiation factor activity [ISS]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLKPYRPKS SAALKGSDSK KFRQRVEAAF PHVSVDQLVP AKAAVTQVKI LTHGGVQSMV  60
   61 YCVDKLPLFF ELDGGQLVPT LYTLWIVPDI LPYFTTHEGV LPKLTNGADL MLPGVVPLGV 120
  121 GLSMYGHFKK GQLMAVNLTN NKSAVGVGQL ARSSDELYMC GGHGVAIKML HLFGDKLWSH 180
  181 EPSLVQQIPL VKTKALSGED FPALGSETER RKTASPATPA PVTFATVAQT EELETETAAL 240
  241 TLESQEAPES DEEAVEEASP ELILKNAFLS ALKNHGKKLP LPLLTSNFYR LYVVTEATEQ 300
  301 IDLKKTRYKK LSNFLAEMVD QGFIVVREES KGVDKITSVD LEHPEVVNFI TDVKASEANG 360
  361 AASETPLFHS ELKEMYIVTD VTAAFFTKLN YKRGEGIPAG QIKKIVREYV SKHGLLHPLT 420
  421 KLVRPDDTLI ELYGNREVSL SEMCSLITSK MEHSYQMCSG KDTSGKPLIQ MSLATRSGNK 480
  481 KVTLVSNIEA YGIILAEFIK LCKQGAAAST SVVKLPHQKH EQLQIQGNQV RFVHTLLTET 540
  541 YKVPPKCILG LELAKDGKKN KKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] PSI-BLAST 29.69897 No description for 2ausC was found.
    2 View Details [190..305] MSA 1.061987 View MSA. No confident structure predictions are available.
    3 View Details [306..459] PSI-BLAST 3.522879 Solution structure of the SWIB/MDM2 domain of the hypothetical protein At5g08430 from Arabidopsis thaliana
    4 View Details [460..563] PSI-BLAST 27.221849 HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • structural molecule activity
    		•  4.76083886363836 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.93337598023804 bayes_pls_golite062009
  • binding
    		•  1.65769778151884 bayes_pls_golite062009
  • protein binding
    		•  1.3501672529352 bayes_pls_golite062009
  • basal transcription repressor activity
    		•  0.955353508790079 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.6943850197604 bayes_pls_golite062009
  • transcription activator activity
    		•  0.51230769371834 bayes_pls_golite062009
  • transcription factor binding
    		•  0.39586576704049 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.35852024786909 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.31113344049068 bayes_pls_golite062009
  • catalytic activity
    		•  0.121624777548864 bayes_pls_golite062009
    4
    Term Confidence Notes
  • translation initiation factor activity
    		•  6.56930940751046 bayes_pls_golite062009
  • translation regulator activity
    		•  2.27579767245564 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  2.25914933413253 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.69119554284364 bayes_pls_golite062009
  • binding
    		•  1.40632629011845 bayes_pls_golite062009
  • protein binding
    		•  0.189517592830504 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle