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Protein Overview: beta4GalNAcTB-PA

General Information:
Name(s) found: beta4GalNAcTB-PA / FBpp0084788 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Ã?&#142;Ã?²4GalNAcTB is referred to in FlyBase by the symbol Dmel\Ã?&#142;Ã?²4GalNAcTB (CG14517, FBgn0039625). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:24858382..24859730. It has the cytological map location 98F5. There is experimental evidence that it has the molecular function</span>: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity; acetylgalactosaminyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: N-acetylglucosamine metabolic process; glycolipid biosynthetic process. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: Golgi apparatus [IDA]
    Biological Process: glycolipid biosynthetic process [IDA]
    N-acetylglucosamine metabolic process [IDA]
    Molecular Function: acetylgalactosaminyltransferase activity [IDA]
    N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVRLWVRSF HKYDLLIAIG LITLIVYLCL PFRFASHYDY IEESKIEGAL VPQVTRNVSQ  60
   61 QEVFECTYSE IIAENRFVYH LAHYHDAVQR GAEIRPGGEF RPEGCQARYS TAIIVPYRQR 120
  121 EEQLHAFLTY MHNYLPQQLI HYRIFLVEQF DHKPFNRAML FNIGAQVAAE YGFPCLILHD 180
  181 VDLLPLNSGQ IYACSERPRH MSSALDHWRF RLPYRGLFGG VVAINTAQYQ QINGMSNLYY 240
  241 GWGGEDDDLY ERLQALNIDI CRFAMEFSKY TMLKHKQEQP NANRVALLRS ATLRQHADGL 300
  301 NSLVYTEMER RMHSLFTHIL VDT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..323] PSI-BLAST 98.69897 beta 1,4 galactosyltransferase (b4GalT1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  8.87768693404638 bayes_pls_golite062009
  • lactose synthase activity
    		•  6.70934342374853 bayes_pls_golite062009
  • N-acetyllactosamine synthase activity
    		•  6.70934342374853 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  6.50620584399191 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  6.18010634203776 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  5.57855076532185 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  4.57071306027628 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  4.49413422196176 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  3.80392076707564 bayes_pls_golite062009
  • glucuronosyltransferase activity
    		•  3.57513377728523 bayes_pls_golite062009
  • transferase activity
    		•  2.62166586999833 bayes_pls_golite062009
  • UDP-galactosyltransferase activity
    		•  2.58196286090865 bayes_pls_golite062009
  • galactosyltransferase activity
    		•  2.49617255507474 bayes_pls_golite062009
  • heparan sulfate N-acetylglucosaminyltransferase activity
    		•  2.42139682088952 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.01768771829228 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
    		•  1.6603302881547 bayes_pls_golite062009
  • beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
    		•  1.33105118629174 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.31793036737589 bayes_pls_golite062009
  • N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
    		•  1.11758321292207 bayes_pls_golite062009
  • protein binding
    		•  0.967722609820275 bayes_pls_golite062009
  • alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
    		•  0.734643988700831 bayes_pls_golite062009
  • binding
    		•  0.667238976803188 bayes_pls_golite062009
  • UDP-N-acetylglucosamine diphosphorylase activity
    		•  0.513376694534047 bayes_pls_golite062009
  • uridylyltransferase activity
    		•  0.321928989676507 bayes_pls_golite062009
  • mannose-phosphate guanylyltransferase activity
    		•  0.2363835251362 bayes_pls_golite062009
  • cytidylyltransferase activity
    		•  0.218759888732981 bayes_pls_golite062009
  • glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
    		•  0.119213830545019 bayes_pls_golite062009
  • guanylyltransferase activity
    		•  0.0539392112504681 bayes_pls_golite062009
  • mannose-1-phosphate guanylyltransferase activity
    		•  0.040911758618571 bayes_pls_golite062009
  • acetylglucosaminyltransferase activity
    		•  0.0278258721775009 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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