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Protein Overview: FBpp0088624, FBp...

General Information:
Name(s) found: larp-PE / FBpp0290399 [FlyBase]
FBpp0088624 [FlyBase]
FBpp0088622 [FlyBase]
Description(s) found:
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  • gi|24650802|ref|NP_733245.1| La related protein, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|24650800|ref|NP_524998.1| La related protein, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|23172494|gb|AAN14139.1| La related protein, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|23172493|gb|AAF56783.3| La related protein, isoform A [Drosophila melanogaster] [NCBI NR]
  • The gene La related protein is referred to in FlyBase by the symbol Dmel\larp (CG42551, FBgn0260724). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:24143896..24162162. It has the cytological map location 98C4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitochondrion inheritance; mitotic chromosome condensation; centrosome separation; spindle assembly involved in male meiosis; male meiosis; spindle assembly; autophagic cell death; salivary gland cell autophagic cell death. 34 alleles are reported. The phenotypes of these alleles are annotated with: onion stage spermatid; condensed nuclear chromosome; Nebenkern; macrochaeta; mitotic anaphase; testis; centrosome; spindle; nucleus. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0088624; name=larp-PB; parent=FBgn0261618,FBtr0089682; dbxref=FlyBase:FBpp0088624,GB_protein:AAN14139.1,REFSEQ:NP_733245,GB_protein:AAN14139,FlyBase_Annotation_IDs:CG42551-PB,FlyBase:FBpp0290397,FlyBase_Annotation_IDs:CG14066-PB; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0088622; name=larp-PA; parent=FBgn0261618,FBtr0089680; dbxref=FlyBase:FBpp0088622,GB_protein:AAF56783.3,REFSEQ:NP_524998,GB_protein:AAF56783,FlyBase_Annotation_IDs:CG42551-PA,FlyBase:FBpp0290396,FlyBase_Annotation_IDs:CG14066-PA; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.56; species=Dmel; [FlyBase]
  • >CG14066-PB translation from_gene[CG14066 larp FBgn0040108] seq_release:3 mol_weight=106221 cds_boundaries:(3R:24,135,673..24,138,822[-]) aa_length:965 transcript_info:[CG14066-RB seq_release:3] gene_info:[gene symbol:larp FLAGGED_PROBLEMATIC FBgn00401 [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG14066-PA translation from_gene[CG14066 larp FBgn0040108] seq_release:3 mol_weight=106221 cds_boundaries:(3R:24,135,673..24,138,822[-]) aa_length:965 transcript_info:[CG14066-RA seq_release:3] gene_info:[gene symbol:larp FLAGGED_PROBLEMATIC FBgn00401 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VAW5) CG14066 protein [DrosMelano7227.FASTAC.txt]
  • CG14066-PB, isoform B [Drosophila melanogaster]gi|23172493|gb|AAF56783.3| CG14066-PA, isoform A [Drosophila melanogaster]gi|24650802|ref|NP_733245.1| CG14066-PB [Drosophila melanogaster]gi|24650800|ref|NP_524998.1| CG14066-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290396; name=larp-PA; parent=FBgn0260724,FBtr0301178; dbxref=FlyBase:FBpp0290396,FlyBase_Annotation_IDs:CG42551-PA,FlyBase:FBpp0088622,FlyBase_Annotation_ID [fly-100309-contam.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290397; name=larp-PB; parent=FBgn0260724,FBtr0301179; dbxref=FlyBase:FBpp0290397,FlyBase_Annotation_IDs:CG42551-PB,FlyBase:FBpp0088624,FlyBase_Annotation_ID [fly-100309-contam.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290399; name=larp-PE; parent=FBgn0260724,FBtr0301181; dbxref=FlyBase:FBpp0290399,FlyBase_Annotation_IDs:CG42551-PE; MD5=57821b32386f53c8af5ae5196c129f7c; le [fly-100309-contam.fasta]
  • CG14066-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG14066-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • La related protein CG14066-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • La related protein CG14066-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • La related protein, isoform E [Drosophila melanogaster] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • La related protein, isoform B [Drosophila melanogaster] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • La related protein, isoform A [Drosophila melanogaster] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290396; name=larp-PA; parent=FBgn0260724,FBtr0301178; dbxref=FlyBase:FBpp0290396,FlyBase_Annotation_IDs:CG42551-PA,FlyBase:FBpp0088622,FlyBase_Annotation_IDs:CG14066-PA; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290397; name=larp-PB; parent=FBgn0260724,FBtr0301179; dbxref=FlyBase:FBpp0290397,FlyBase_Annotation_IDs:CG42551-PB,FlyBase:FBpp0088624,FlyBase_Annotation_IDs:CG14066-PB; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290399; name=larp-PE; parent=FBgn0260724,FBtr0301181; dbxref=FlyBase:FBpp0290399,FlyBase_Annotation_IDs:CG42551-PE; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290396; name=larp-PA; parent=FBgn0260724,FBtr0301178; dbxref=FlyBase:FBpp0290396,FlyBase_Annotation_IDs:CG42551-PA,FlyBase:FBpp0088622,FlyBase_Annotation_IDs:CG14066-PA; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290397; name=larp-PB; parent=FBgn0260724,FBtr0301179; dbxref=FlyBase:FBpp0290397,FlyBase_Annotation_IDs:CG42551-PB,FlyBase:FBpp0088624,FlyBase_Annotation_IDs:CG14066-PB; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290399; name=larp-PE; parent=FBgn0260724,FBtr0301181; dbxref=FlyBase:FBpp0290399,FlyBase_Annotation_IDs:CG42551-PE; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Isoform A of La-related protein OS=Drosophila melanogaster GN=larp [UniProt_drosophila_07-01-2011_reversed.fasta]
  • La related protein, isoform E OS=Drosophila melanogaster GN=larp PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0088624; name=larp-PB; parent=FBgn0261618,FBtr0089682; dbxref=FlyBase:FBpp0088624,GB_protein:AAN14139.1,REFSEQ:NP_733245,GB_protein:AAN14139,FlyBase_Annotation_IDs:CG42551-PB,FlyBase:FBpp0290397,FlyBase_Annotation_IDs:CG14066-PB; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0088622; name=larp-PA; parent=FBgn0261618,FBtr0089680; dbxref=FlyBase:FBpp0088622,GB_protein:AAF56783.3,REFSEQ:NP_524998,GB_protein:AAF56783,FlyBase_Annotation_IDs:CG42551-PA,FlyBase:FBpp0290396,FlyBase_Annotation_IDs:CG14066-PA; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(24146304..24147001,24147095..24149208,24149371..24149456); ID=FBpp0290399; name=larp-PE; parent=FBgn0261618,FBtr0301181; dbxref=REFSEQ:NP_001163757,GB_protein:ACZ95051,FlyBase:FBpp0290399,FlyBase_Annotation_IDs:CG42551-PE; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0088624; name=larp-PB; parent=FBgn0261618,FBtr0089682; dbxref=FlyBase:FBpp0088624,GB_protein:AAN14139.1,REFSEQ:NP_733245,GB_protein:AAN14139,FlyBase_Annotation_IDs:CG42551-PB,FlyBase:FBpp0290397,FlyBase_Annotation_IDs:CG14066-PB; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0088622; name=larp-PA; parent=FBgn0261618,FBtr0089680; dbxref=FlyBase:FBpp0088622,GB_protein:AAF56783.3,REFSEQ:NP_524998,GB_protein:AAF56783,FlyBase_Annotation_IDs:CG42551-PA,FlyBase:FBpp0290396,FlyBase_Annotation_IDs:CG14066-PA; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0290399; name=larp-PE; parent=FBgn0261618,FBtr0301181; dbxref=REFSEQ:NP_001163757,GB_protein:ACZ95051,FlyBase:FBpp0290399,FlyBase_Annotation_IDs:CG42551-PE; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0088624; name=larp-PB; parent=FBgn0261618,FBtr0089682; dbxref=FlyBase:FBpp0088624,GB_protein:AAN14139.1,REFSEQ:NP_733245,GB_protein:AAN14139,FlyBase_Annotation_IDs:CG42551-PB,FlyBase:FBpp0290397,FlyBase_Annotation_IDs:CG14066-PB; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0088622; name=larp-PA; parent=FBgn0261618,FBtr0089680; dbxref=FlyBase:FBpp0088622,GB_protein:AAF56783.3,REFSEQ:NP_524998,GB_protein:AAF56783,FlyBase_Annotation_IDs:CG42551-PA,FlyBase:FBpp0290396,FlyBase_Annotation_IDs:CG14066-PA; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0290399; name=larp-PE; parent=FBgn0261618,FBtr0301181; dbxref=REFSEQ:NP_001163757,GB_protein:ACZ95051,FlyBase:FBpp0290399,FlyBase_Annotation_IDs:CG42551-PE; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VAW5, Isoform A of La-related protein 1 OS=Drosophila melanogaster GN=larp [DROME.fasta.20160308]
  • FBpp0088624 type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0088624; name=larp-PB; parent=FBgn0261618,FBtr0089682; dbxref=FlyBase:FBpp0088624,GB_protein:AAN14139.1,REFSEQ:NP_733245,GB_protein:AAN14139,FlyBase_Annotation_IDs:CG42551-PB,FlyBase:FBpp0290397,FlyBase_Annotation_IDs:CG14066-PB; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0088622 type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0088622; name=larp-PA; parent=FBgn0261618,FBtr0089680; dbxref=FlyBase:FBpp0088622,GB_protein:AAF56783.3,REFSEQ:NP_524998,GB_protein:AAF56783,FlyBase_Annotation_IDs:CG42551-PA,FlyBase:FBpp0290396,FlyBase_Annotation_IDs:CG14066-PA; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0290399 type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0290399; name=larp-PE; parent=FBgn0261618,FBtr0301181; dbxref=REFSEQ:NP_001163757,GB_protein:ACZ95051,FlyBase:FBpp0290399,FlyBase_Annotation_IDs:CG42551-PE; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0088624; name=larp-PB; parent=FBgn0261618,FBtr0089682; dbxref=FlyBase:FBpp0088624,GB_protein:AAN14139.1,REFSEQ:NP_733245,GB_protein:AAN14139,FlyBase_Annotation_IDs:CG42551-PB,FlyBase:FBpp0290397,FlyBase_Annotation_IDs:CG14066-PB,UniProt/TrEMBL:F9W345; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0088622; name=larp-PA; parent=FBgn0261618,FBtr0089680; dbxref=FlyBase:FBpp0088622,GB_protein:AAF56783.3,REFSEQ:NP_524998,GB_protein:AAF56783,FlyBase_Annotation_IDs:CG42551-PA,FlyBase:FBpp0290396,FlyBase_Annotation_IDs:CG14066-PA,UniProt/TrEMBL:F9W345; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:complement(join(28323649..28323734,28321373..28323486,28320582..28321279)); ID=FBpp0290399; name=larp-PE; parent=FBgn0261618,FBtr0301181; dbxref=REFSEQ:NP_001163757,GB_protein:ACZ95051,FlyBase:FBpp0290399,FlyBase_Annotation_IDs:CG42551-PE,UniProt/TrEMBL:F9W345; MD5=57821b32386f53c8af5ae5196c129f7c; length=965; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 965 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTHYFGNVP AAYIELDANS IKEAIKKQVE YYFSVDNLTG DFFLRRKMDP EGYIPVTLIA  60
   61 SFHRVLALTT DVAVIVNAIK ESDKLELFEG YKVRTKTTPT TWPITEVPEV NEGEPKAIGT 120
  121 LEQEQLEQND GQEKLEEQTE ADSPPPILTS AMATKPLNSI PPPPMPRNPQ NLVPKMLQDK 180
  181 QQSRSSTIAA LNSVNAISAL TQQVEGGAAE LAGHLSGLAE SVKPKSTSTP DKRNAASAGN 240
  241 GAGSAAALVA EPEGIWKEVK RRSKTNAIKE NATTPPQQQQ PPLSQTLNNN NDNVKTNNTS 300
  301 SKSKSSSNNA PSNASSSATV CVTTNNASSA TKATTKTTTT STATTTTNNN IKSGNAAYSK 360
  361 THSKSSSKTA APPSAQCHAE KEELDFQFDE ELMDPLPPGT GRINNFTENF SDDDESDYEF 420
  421 ADRDINKLLI VAQVGRAPKH EGYDRTADFT SRTKITQDLE NIINDGLVNY EEDLWTTTNV 480
  481 VADYKTVNVI SQADFEKLAG GRNKSVLPPQ VVPPPPPFEE DLDETLVGDT TLNSTLNNTL 540
  541 KSRRARFYAA PNSHSIDPRT PRKRKLRHTA NPPVEAHVGW LLDTVEHRPR TTSMGSSAGT 600
  601 SPTASSYGSF GSSVPQSLPV FQHPSHALLK ENNFTQQAYH KYHSRCLKER RRLGYGQSQE 660
  661 MNTLYRFWSF FLRENFNKSM YNEFRSLALE DAGNGFRYGL ECLFRFFSYG LEKKFRPNIY 720
  721 QDFQDETIAD YETGQLYGLE KFWAFLKYYK NGEKLEVQPK LAEYLKSFKN IEDFRVVEPE 780
  781 INEMLQGVGS LNPGRQLNRH RSVSESDGTA VIAAGGRRLN TTITNRSDYV GRLLQQQHQQ 840
  841 QQQQQHHQYQ QGYGGYNQQQ NRRRTGSFGS TTVRIRSGSL GNKPQVANRN QGSQHELRRG 900
  901 GSNSGLAPHK RQQQQKPKPG AGSQTGSTRA TTSAAATATT AASAATSTAA TPAVTVSSGS 960
  961 SSSKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] PSI-BLAST 24.0 Solution structure of the La domain of c-Mpl binding protein
    2 View Details [95..190] deduced N/A No confident structure predictions are available.
    3 View Details [191..381] MSA 2.256995 View MSA. No confident structure predictions are available.
    4 View Details [382..529] deduced N/A No confident structure predictions are available.
    5 View Details [530..645] MSA 2.255988 View MSA. No confident structure predictions are available.
    6 View Details [646..831] MSA 1.030959 View MSA. No confident structure predictions are available.
    7 View Details [832..965] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.835523092977445 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.4843036104266 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.37117756729668 bayes_pls_golite062009
  • DNA binding
    		•  0.3118855114645 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle