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Protein Overview: ALiX-PA

General Information:
Name(s) found: ALiX-PA / FBpp0084610 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene ALG-2 interacting protein X is referred to in FlyBase by the symbol Dmel\ALiX (CG12876, FBgn0086346). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23522187..23525967. It has the cytological map location 98B1. Based on sequence similarity, it is predicted to have molecular function</span>: signal transducer activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of JNK cascade; actin filament polymerization. 9 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing hair. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 836 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: positive regulation of JNK cascade [IDA][NAS]
    apoptosis [NAS]
    actin filament polymerization [IMP]
    Molecular Function: signal transducer activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKFLGVPLK KPSEVDVIKP LNNLIQSTYN GASEEEKGKY GEAVNEFSKQ RNTAIWKFFE  60
   61 KYEASLEIVY AYYDQICALE TKISVSELQI PFKWKDAFDK GSIFGGKISL THTSLLYEKV 120
  121 CVLFNIAALQ SNIAANQSLD SDDGLKLTIK LLQQSAGIFQ YLKGATPAAV PSEPTPDLSQ 180
  181 DTLTVLQALM VAQAQEVFIL KAIKDNLKDQ IIAKLCCQAE ESYADVLRAM QKESVRSLWE 240
  241 KEWIPTIAGK QAGFHALTQL YQSLVCRAAK KIGEEIARLR NAIDLFKAAQ TRSGNETYLD 300
  301 EYFSRAKRNL TESTKDNEFI YNEIIPELST LTSPGKAQLA KPLPIAVPLA ENFKDIFSSL 360
  361 VPVELHRALT ASDMRRNEIV NVEIMKLREA TQTLNAVLAS LNLPAAVETA DGNSGLPPSL 420
  421 KEKANEVRQK GGIENVQTML KDLPELLNRN REILDETERL LDEERDSDNQ LRAQFKDRWT 480
  481 RISSDKLTEM FRTNAKKYRE VITNAIEADK VVRQKFEANQ KGIQLLSLPP DQIQQSLPSA 540
  541 SGSVDPNCSS VQRLKKLMDD VETIKAEREA IESELKGATF NMKDEFLIAL QKDGAIDEPA 600
  601 LSLARIGQVL NPLQQQVRES VERQQSLVSE IQSAHGAFVS ETGSCGSSRD TLYQELATAF 660
  661 DSYIELSGNL QEGTKFYNDL TQLLVVFQNK ISDFVFARKT EKEELLKDLT TESSRQACPA 720
  721 TPALPSHYAS TSGSGSDIPP GSAPSVPPAA STANIPYPAQ VQGMPIPYGA QPGVPYPAYV 780
  781 PAPMPQSFNP YATLPYPGNY QYQGFPQGPP PGHYGTYPGS YANQQGGYPN QKPPGW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..711] PSI-BLAST 67.30103 No description for 2oevA was found.
    2 View Details [712..836] FFAS03 1.03 No description for 2j63A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle