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Protein Overview: CG5590-PA

General Information:
Name(s) found: CG5590-PA / FBpp0084585 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5590 (CG5590, FBgn0039537). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23503297..23504738. It has the cytological map location 98B1. Based on sequence similarity, it is predicted to have molecular function</span>: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 412 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    Biological Process: oxidation reduction [IEA]
    Molecular Function: sterol binding [IEA]
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MINTGKLAGR TLFITGASRG IGKEIALKAA RDGANIVVAA KTAEPHPKLP GTIYSAAEEI  60
   61 EKAGGKAYPC VVDVRDEQQV RSAVEAAVAK FGGIDIVINN ASAISLTNTP DTDMKRYDLM 120
  121 HNINTRGTFL VSKVCLPYLK KSNHAHILNI SPPLSMKPKW FGPHVAYTMA KYGMSMCVLG 180
  181 MAAEFKDEGI SVNALWPRTA IHTAAIEMLT GPDSAKWSRK PEIMADAAYA ILTREPRQST 240
  241 GQFFVDDEVL ESAGITDLTE YACFRENADK LMVDFFVEEK GAPVENEAAA EDAAAPASGG 300
  301 DVKIPQLFRK IESLLSPEIV SKTQAVFQFN ISGAEQGTWF LDLKNGSGSC GAGTPTAAPD 360
  361 ATLTMNSKNF FDMFSGKLKA APAYMTGKLK ISGDFQKALK LEKLMKALKS KL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..299] PSI-BLAST 49.154902 Crystal Structure Of Human 17-Beta-Hydroxysteroid Dehydrogenase Type 4 In Complex With NAD
    2 View Details [300..412] PSI-BLAST 32.522879 SCP2-like domain of MFE-2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.69771604880532 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  1.23679054027553 bayes_pls_golite062009
  • 3-oxoacyl-[acyl-carrier-protein] reductase activity
    		•  0.604742541607263 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  0.54910246066113 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.418775403210681 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.32207755075663 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.196071455245233 bayes_pls_golite062009
    2
    Term Confidence Notes
  • sterol carrier protein X-related thiolase activity
    		•  1.71600951762874 bayes_pls_golite062009
  • sterol binding
    		•  0.77874943487633 bayes_pls_golite062009
  • lipid binding
    		•  0.612082389575099 bayes_pls_golite062009
  • catalytic activity
    		•  0.334051377480817 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle