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View Structure Prediction Details

Protein: CG5590-PA
Organism: Drosophila melanogaster
Length: 412 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5590-PA.

Description E-value Query
Range
Subject
Range
gi|91088497 - gi|91088497|ref|XP_971106.1| PREDICTED: similar to short-chain dehydrogenase [Tribolium castaneum]
374.0 [0..1] [412..1]

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Predicted Domain #1
Region A:
Residues: [1-299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MINTGKLAGR TLFITGASRG IGKEIALKAA RDGANIVVAA KTAEPHPKLP GTIYSAAEEI  60
   61 EKAGGKAYPC VVDVRDEQQV RSAVEAAVAK FGGIDIVINN ASAISLTNTP DTDMKRYDLM 120
  121 HNINTRGTFL VSKVCLPYLK KSNHAHILNI SPPLSMKPKW FGPHVAYTMA KYGMSMCVLG 180
  181 MAAEFKDEGI SVNALWPRTA IHTAAIEMLT GPDSAKWSRK PEIMADAAYA ILTREPRQST 240
  241 GQFFVDDEVL ESAGITDLTE YACFRENADK LMVDFFVEEK GAPVENEAAA EDAAAPASG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.154902
Match: 1zbqA
Description: Crystal Structure Of Human 17-Beta-Hydroxysteroid Dehydrogenase Type 4 In Complex With NAD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity 1.69771604880532 bayes_pls_golite062009
fatty acid synthase activity 1.23679054027553 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.604742541607263 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 0.54910246066113 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.418775403210681 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.32207755075663 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.196071455245233 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [300-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDVKIPQLFR KIESLLSPEI VSKTQAVFQF NISGAEQGTW FLDLKNGSGS CGAGTPTAAP  60
   61 DATLTMNSKN FFDMFSGKLK AAPAYMTGKL KISGDFQKAL KLEKLMKALK SKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.522879
Match: 1iktA
Description: SCP2-like domain of MFE-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sterol carrier protein X-related thiolase activity 1.71600951762874 bayes_pls_golite062009
sterol binding 0.77874943487633 bayes_pls_golite062009
lipid binding 0.612082389575099 bayes_pls_golite062009
catalytic activity 0.334051377480817 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle