YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: Mdh-PA

General Information:
Name(s) found: Mdh-PA / FBpp0084480 [FlyBase]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • The gene Mdh is referred to in FlyBase by the symbol Dmel\Mdh (CG5889, FBgn0029155). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:22977363..22983325. It has the cytological map location 97E5. Based on sequence similarity, it is predicted to have molecular function</span>: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: pyruvate metabolic process; malate metabolic process. 14 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 617 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISS]
    Biological Process: malate metabolic process [ISS]
    oxidation reduction [IEA]
    pyruvate metabolic process [ISS]
    Molecular Function: metal ion binding [IEA]
    NAD or NADH binding [IEA]
    malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSRPSLCGT VGKLCRCGTS ATGKTAVAAA TVPTARHYHE VVGDIICPSQ VRGIDHIRDP  60
   61 RLNKGLAFTL EERQTLGIHG LQPARFKTQE EQLQLCKIAV NRYTEPLNKY LYLSDLYDRN 120
  121 ERLFFRFLSE NIEDLMPIVY TPTVGLACQR FGLIYRRPHG LFITYNDRGH IFDVMKNWPE 180
  181 PNVRAICVTD GERILGLGDL GACGMGIPVG KLALYTALAG IKPHQCLPIV VDVGTNNIDL 240
  241 LEDPLYVGLR QKRVVGREYD EFIDEFMEAV VQRYGQNTLI QFEDFGNHNA FRFLDKYRNT 300
  301 YCTFNDDIQG TASVAVAGLY ASKRITGKSF KDYTFLFAGA GEAAIGIADL TVKAMVQDGV 360
  361 PIEEAYNRIY MVDIDGLLTK SRKVGNLDGH KIHYAKDINP MSDLAEIVST IKPSVLIGAS 420
  421 AAAGIFTPEI LRTMADNNER PVVFALSNPT SKAECTAEDA YKHTDARVIF SSGSPFPPVQ 480
  481 IGDKTFYPGQ GNNAYIFPGV GLGVICTGTH HIPDEMFLIA AQELANFVEP SDIERGSLYP 540
  541 PLSSIRNVSM NIAVGVTKCA YDRGLASTYP EPQDKRKWLE NQLYNFNYES SMPASWVWPR 600
  601 MPYIKTREES PLIAAIK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..617] PSI-BLAST 1000.0 Crystal structure of a human malic enzyme


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.47

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle