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Protein Overview: CG31075-PA

General Information:
Name(s) found: CG31075-PA / FBpp0084452 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG31075 (CG31075, FBgn0051075). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:22811344..22814237. It has the cytological map location 97D12. Based on sequence similarity, it is predicted to have molecular function</span>: aldehyde dehydrogenase (NAD) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: pyruvate metabolic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 485 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISS]
    mitochondrion [ISS]
    Biological Process: oxidation reduction [IEA]
    pyruvate metabolic process [ISS]
    Molecular Function: aldehyde dehydrogenase (NAD) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADPNAKPKY TKLFINNEFV DSVSGKTFAT FNPATSKEIV QVSEGDKADI DLAVKAAKKA  60
   61 FHRDSEWRKL SPLQRTNLMN KLCALMDRDK AFLASLETQD NGKPYAEALF DVTYSILTLQ 120
  121 YYAGWTDKFF GDTIPAGGFV SMTRKEPVGV VGQIIPWNYP LLMLAWKWGP ALAVGCTIIM 180
  181 KPAEQTPLTA LHMAALAKEA GFPAGVINVV NGFGPTAGAA ISAHPDIAKV AFTGSVEIGR 240
  241 IVMQAAATSN LKRVSLELGG KSPVVVFDDA DIDFAVETTH EALFSNHGQS CCAGSRTYVH 300
  301 EKIYDEFVAK AAAKAKARKV GNPFEQNVQQ GPQIDDDMLT KVLGYIESGK KEGAKLQAGG 360
  361 KRIGNVGFFV EPTVFSDVKD DMRIAQEEIF GPVQSIFKFS SLEEMIDRAN NVQYGLAAGV 420
  421 ITNDINKALK FANNVDAGSV WINCYDAVLP STPFGGYKHS GIGRELGKDG LDNYLETKTI 480
  481 TMKLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..485] PSI-BLAST 175.0 Aldehyde reductase (dehydrogenase), ALDH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  5.09598561374689 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.47226217021998 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  4.35175408702761 bayes_pls_golite062009
  • malonate-semialdehyde dehydrogenase (acetylating) activity
    		•  4.2273960318884 bayes_pls_golite062009
  • methylmalonate-semialdehyde dehydrogenase (acylating) activity
    		•  3.87605237828483 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase [NAD(P)+] activity
    		•  3.64672165191647 bayes_pls_golite062009
  • 3-chloroallyl aldehyde dehydrogenase activity
    		•  3.37049090049734 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  3.2867555127991 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  2.99564252244797 bayes_pls_golite062009
  • aldehyde dehydrogenase (NAD) activity
    		•  2.81851373615334 bayes_pls_golite062009
  • catalytic activity
    		•  2.80804701752928 bayes_pls_golite062009
  • glutamate-5-semialdehyde dehydrogenase activity
    		•  2.78416888468693 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase activity
    		•  2.71501590413507 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  2.70230501280821 bayes_pls_golite062009
  • aldehyde dehydrogenase [NAD(P)+] activity
    		•  2.43250909158896 bayes_pls_golite062009
  • aminobutyraldehyde dehydrogenase activity
    		•  2.35958138496479 bayes_pls_golite062009
  • acyl-CoA binding
    		•  2.26220696569489 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  1.6559690223037 bayes_pls_golite062009
  • retinal dehydrogenase activity
    		•  1.42867174920845 bayes_pls_golite062009
  • binding
    		•  1.06673666884196 bayes_pls_golite062009
  • retinoid binding
    		•  0.983782635681687 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.900374761028287 bayes_pls_golite062009
  • protein binding
    		•  0.894945263794726 bayes_pls_golite062009
  • histidinol dehydrogenase activity
    		•  0.258030369394064 bayes_pls_golite062009
  • benzaldehyde dehydrogenase (NAD+) activity
    		•  0.23487570676521 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle