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View Structure Prediction Details

Protein: CG31075-PA
Organism: Drosophila melanogaster
Length: 485 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG31075-PA.

Description E-value Query
Range		 Subject
Range
gi|20372798 - gi|20372798|emb|CAD30313.1| aldehyde dehydrogenase [Geobacillus stearothermophilus]
 612.0 [0..12] [482..21]

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Predicted Domain #1
Region A:
Residues: [1-485] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADPNAKPKY TKLFINNEFV DSVSGKTFAT FNPATSKEIV QVSEGDKADI DLAVKAAKKA  60
   61 FHRDSEWRKL SPLQRTNLMN KLCALMDRDK AFLASLETQD NGKPYAEALF DVTYSILTLQ 120
  121 YYAGWTDKFF GDTIPAGGFV SMTRKEPVGV VGQIIPWNYP LLMLAWKWGP ALAVGCTIIM 180
  181 KPAEQTPLTA LHMAALAKEA GFPAGVINVV NGFGPTAGAA ISAHPDIAKV AFTGSVEIGR 240
  241 IVMQAAATSN LKRVSLELGG KSPVVVFDDA DIDFAVETTH EALFSNHGQS CCAGSRTYVH 300
  301 EKIYDEFVAK AAAKAKARKV GNPFEQNVQQ GPQIDDDMLT KVLGYIESGK KEGAKLQAGG 360
  361 KRIGNVGFFV EPTVFSDVKD DMRIAQEEIF GPVQSIFKFS SLEEMIDRAN NVQYGLAAGV 420
  421 ITNDINKALK FANNVDAGSV WINCYDAVLP STPFGGYKHS GIGRELGKDG LDNYLETKTI 480
  481 TMKLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 175.0
Match: 1bxsA
Description: Aldehyde reductase (dehydrogenase), ALDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on the aldehyde or oxo group of donors 5.09598561374689 bayes_pls_golite062009
oxidoreductase activity 4.47226217021998 bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity 4.35175408702761 bayes_pls_golite062009
malonate-semialdehyde dehydrogenase (acetylating) activity 4.2273960318884 bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity 3.87605237828483 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity 3.64672165191647 bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity 3.37049090049734 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3.2867555127991 bayes_pls_golite062009
benzaldehyde dehydrogenase activity 2.99564252244797 bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity 2.81851373615334 bayes_pls_golite062009
catalytic activity 2.80804701752928 bayes_pls_golite062009
glutamate-5-semialdehyde dehydrogenase activity 2.78416888468693 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity 2.71501590413507 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors 2.70230501280821 bayes_pls_golite062009
aldehyde dehydrogenase [NAD(P)+] activity 2.43250909158896 bayes_pls_golite062009
aminobutyraldehyde dehydrogenase activity 2.35958138496479 bayes_pls_golite062009
acyl-CoA binding 2.26220696569489 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1.6559690223037 bayes_pls_golite062009
retinal dehydrogenase activity 1.42867174920845 bayes_pls_golite062009
binding 1.06673666884196 bayes_pls_golite062009
retinoid binding 0.983782635681687 bayes_pls_golite062009
isoprenoid binding 0.900374761028287 bayes_pls_golite062009
protein binding 0.894945263794726 bayes_pls_golite062009
histidinol dehydrogenase activity 0.258030369394064 bayes_pls_golite062009
benzaldehyde dehydrogenase (NAD+) activity 0.23487570676521 bayes_pls_golite062009
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