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Protein Overview: m2-PA

General Information:
Name(s) found: m2-PA / FBpp0084354 [FlyBase]
Description(s) found:
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  • gi|7301423|gb|AAF56549.1| E(spl) region transcript m2 [Drosophila melanogaster] [NCBI NR]
  • gi|55715442|gb|AAV59234.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715429|gb|AAV59222.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715403|gb|AAV59198.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715377|gb|AAV59174.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715338|gb|AAV59138.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715325|gb|AAV59126.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715312|gb|AAV59114.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715273|gb|AAV59078.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715260|gb|AAV59066.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715247|gb|AAV59054.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715061|gb|AAV59039.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715059|gb|AAV59038.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715057|gb|AAV59037.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715055|gb|AAV59036.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715053|gb|AAV59035.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715051|gb|AAV59034.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715049|gb|AAV59033.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715047|gb|AAV59032.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715043|gb|AAV59030.1| enhancer of split m2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|4493345|emb|CAB39174.1| M2 protein [Drosophila melanogaster] [NCBI NR]
  • gi|17945323|gb|AAL48718.1| RE15854p [Drosophila melanogaster] [NCBI NR]
  • gi|17738205|ref|NP_524508.1| E(spl) region transcript m2 [Drosophila melanogaster] [NCBI NR]
  • gi|11132203|sp|O97177.1|ESM2_DROME RecName: Full=Enhancer of split M2 protein; Short=E(spl)m2 [NCBI NR]
  • Enhancer of split M2 protein OS=Drosophila melanogaster GN=m2 PE=2 SV=1 [Swiss-Prot]
  • The gene E(spl) region transcript m2 is referred to in FlyBase by the symbol Dmel\m2 (CG6104, FBgn0002592). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21842231..21843192. It has the cytological map location 96F10. Its molecular function is unknown. It is reported to be involved in the biological process</span>: Notch signaling pathway. 5 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; anterior dorsocentral bristle; sensory mother cell; microchaeta; posterior dorsocentral bristle. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG6104-PA translation from_gene[CG6104 m2 FBgn0002592] seq_release:3 mol_weight=24118 cds_boundaries:(3R:21,831,796..21,832,449[-]) aa_length:218 transcript_info:[CG6104-RA seq_release:3] gene_info:[gene symbol:m2 FBgn0002592 gene_boundaries:(3R:21,83 [hmr_yeast5_DM3-1_pombe.fasta]
  • (O97177) Enhancer of split M2 protein (E(spl)m2) [DrosMelano7227.FASTAC.txt]
  • (AE003754) m2 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG6104-PA [Drosophila melanogaster]gi|17945323|gb|AAL48718.1| RE15854p [Drosophila melanogaster]gi|17738205|ref|NP_524508.1| CG6104-PA [Drosophila melanogaster]gi|4493345|emb|CAB39174.1| M2 protein [Drosophila melanogaster]gi|11132203|sp|O97177|ESM2_D [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(21842428..21843084); ID=FBpp0084354; name=m2-PA; parent=FBgn0002592,FBtr0084981; dbxref=FlyBase:FBpp0084354,FlyBase_Annotation_IDs:CG6104-PA,GB_protein:AAF56549.1,REFSEQ:NP_524508,GB_protein:AAF56549; MD5=eea2063cf152597c5b [fly-100309-contam.fasta]
  • E(spl) region transcript m2 CG6104-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • enhancer of split m2 protein [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE15854p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Enhancer of split M2 protein (E(spl)m2) [nr-271106-contam.fasta]
  • M2 protein [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG6104-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(21842428..21843084); ID=FBpp0084354; name=m2-PA; parent=FBgn0002592,FBtr0084981; dbxref=FlyBase:FBpp0084354,FlyBase_Annotation_IDs:CG6104-PA,GB_protein:AAF56549.1,REFSEQ:NP_524508,GB_protein:AAF56549; MD5=eea2063cf152597c5b0ae7a1500638e7; length=218; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(21842428..21843084); ID=FBpp0084354; name=m2-PA; parent=FBgn0002592,FBtr0084981; dbxref=FlyBase:FBpp0084354,FlyBase_Annotation_IDs:CG6104-PA,GB_protein:AAF56549.1,REFSEQ:NP_524508,GB_protein:AAF56549; MD5=eea2063cf152597c5b0ae7a1500638e7; length=218; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(21842428..21843084); ID=FBpp0084354; name=m2-PA; parent=FBgn0002592,FBtr0084981; dbxref=FlyBase:FBpp0084354,FlyBase_Annotation_IDs:CG6104-PA,GB_protein:AAF56549.1,REFSEQ:NP_524508,GB_protein:AAF56549,FlyMine:FBpp0084354,modMine:FBpp0084354; MD5=eea2063cf152597c5b0ae7a1500638e7; length=218; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(26016706..26017362); ID=FBpp0084354; name=E(spl)m2-BFM-PA; parent=FBgn0002592,FBtr0084981; dbxref=FlyBase:FBpp0084354,FlyBase_Annotation_IDs:CG6104-PA,GB_protein:AAF56549.1,REFSEQ:NP_524508,GB_protein:AAF56549,FlyMine:FBpp0084354,modMine:FBpp0084354; MD5=eea2063cf152597c5b0ae7a1500638e7; length=218; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(26016706..26017362); ID=FBpp0084354; name=E(spl)m2-BFM-PA; parent=FBgn0002592,FBtr0084981; dbxref=FlyBase:FBpp0084354,FlyBase_Annotation_IDs:CG6104-PA,GB_protein:AAF56549.1,REFSEQ:NP_524508,GB_protein:AAF56549,FlyMine:FBpp0084354,modMine:FBpp0084354; MD5=eea2063cf152597c5b0ae7a1500638e7; length=218; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0084354 type=protein; loc=3R:complement(26016706..26017362); ID=FBpp0084354; name=E(spl)m2-BFM-PA; parent=FBgn0002592,FBtr0084981; dbxref=FlyBase:FBpp0084354,FlyBase_Annotation_IDs:CG6104-PA,GB_protein:AAF56549.1,REFSEQ:NP_524508,GB_protein:AAF56549,FlyMine:FBpp0084354,modMine:FBpp0084354; MD5=eea2063cf152597c5b0ae7a1500638e7; length=218; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(26016706..26017362); ID=FBpp0084354; name=E(spl)m2-BFM-PA; parent=FBgn0002592,FBtr0084981; dbxref=FlyBase:FBpp0084354,FlyBase_Annotation_IDs:CG6104-PA,GB_protein:AAF56549.1,REFSEQ:NP_524508,GB_protein:AAF56549,UniProt/Swiss-Prot:O97177,FlyMine:FBpp0084354,modMine:FBpp0084354; MD5=eea2063cf152597c5b0ae7a1500638e7; length=218; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 218 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: Notch signaling pathway [NAS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYLDTKNLTA SSTSALTAAT ASNSKSTRRM RNVWKPLSRL LKVGGKGRTA QATLAHPNNV  60
   61 DLNNTQQQQQ QQQQELLIED DTKSTPEESI HKYGLELRQL PEEEQVSLTQ PPNTPTLISS 120
  121 VHVDKVSAQS CGNCQHGRNC QHRHHSSSNI NSSSSSSNMN SSSATQLPSN LWDLQLPLQY 180
  181 ISTDNGTFFW ANTQDRVDDD LLHALLCQSF SQLPGTLC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] MSA 1.003929 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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