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Protein Overview: boss-PA

General Information:
Name(s) found: boss-PA / FBpp0084323 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene bride of sevenless is referred to in FlyBase by the symbol Dmel\boss (CG8285, FBgn0000206). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21787716..21792670. It has the cytological map location 96F8. There is experimental evidence that it has the molecular function</span>: sevenless binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: signal transduction. 53 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R7; eye. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 896 amino acids

    Gene Ontology:
    Cellular Component: microvillus [IDA]
    integral to membrane [IEA][ISS][NAS]
    plasma membrane [NAS]
    Biological Process: R8 cell-mediated photoreceptor organization [NAS]
    response to glucose stimulus [IMP]
    G-protein coupled receptor protein signaling pathway [IEA]
    signal transduction [ISS]
    lipid homeostasis [IMP]
    glucose homeostasis [IMP]
    sevenless signaling pathway [NAS]
    R7 cell fate commitment [TAS]
    R7 cell development [NAS]
    R7 cell differentiation [NAS]
    visual perception [IEA]
    compound eye development [NAS]
    Molecular Function: sevenless binding [IGI][IPI][NAS]
    G-protein coupled receptor activity [IEA][ISS]
    transmembrane receptor activity [ISS]
    receptor binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVMDALQSG RRKPLPVALL CILVTVFCVL ECHGADLTSP TKKSAPLRIT KPQPTSQQAK  60
   61 PISITTRAPT TVASTTDDEV SSSVDGQLAP LISSTTEGPS SGTTASLVPE ICLNGLQLTV 120
  121 NSADEGTVIR KQEEFVKILE GDVVLSVLTK DPDSALFVIN RVNQANLIMA DFEIGIRAIS 180
  181 IDNASLAENL LIQEVQFLQQ CTTYSMGIFV DWELYKQLES VIKDLEYNIW PIPGTRAHLF 240
  241 PKVAHLLHQM PWGEKIASVE IATETLEMYN EFMEAARQEH MCLMHFKSDD NVYIMFGNKL 300
  301 ASHFKENGTL FSVPTDRTDD EFLADLPNRA FVLMENEIDL STAVELDATP TALDEILIGK 360
  361 SVLPSRVLSF AGSIIDLMNW LRGSLSKHCK RGEEHDLYVL ESCFNFLNFI EDWRTSEYRQ 420
  421 AHDTAEILSL LLMRKLGTAM NFQMYQKKVL TLDKITGESR TELREIASQN FVTNVTTYYH 480
  481 YNRDNHTSLE LKTKFGQVFN CQYSAGDNRR YPFLFDGESV MFWRIKMDTW VATGLTAAIL 540
  541 GLIATLAILV FIVVRISLGD VFEGNPTTSI LLLLSLILVF CSFVPYSIEY VGEQRNSHVT 600
  601 FEDAQTLNTL CAVRVFIMTL VYCFVFSLLL CRAVMLASIG SEGGFLSHVN GYIQAVICAF 660
  661 SVVAQVGMSV QLLVVMHVAS ETVSCENIYY GRWLWGLLAY DFALLCCVGA LIPSIYRSQR 720
  721 NYREGILIVI GSVLIMVIWV AWIALSLFGD EWRDAAIPLG LQASGWAVLV GILIPRTFLI 780
  781 VRGIERSDIA QALPSLTSLA FAQNNQYSSE QSVYECVNPA MRHCSQDEVN HQSPSEIPTL 840
  841 PLRGGGPRRQ QFFANLRQAN ANINPQRPPP RPQQSPSRSS VSSLPPSPDH NKITRF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..297] deduced N/A No confident structure predictions are available.
    2 View Details [298..518] PSI-BLAST 51.154902 No description for 2e4uA was found.
    3 View Details [519..808] FFAS03 1.32 Rhodopsin
    4 View Details [809..896] FFAS03 1.07 human APP core domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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