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Protein Overview: CG17370-PA, CG17...

General Information:
Name(s) found: FBpp0310535 [FlyBase]
CG17370-PC / FBpp0084285 [FlyBase]
CG17370-PB / FBpp0084284 [FlyBase]
CG17370-PA / FBpp0084283 [FlyBase]
Description(s) found:
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  • gi|7301395|gb|AAF56522.1| CG17370, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|7301394|gb|AAF56521.1| CG17370, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|24650175|ref|NP_733124.1| CG17370, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|24650173|ref|NP_733123.1| CG17370, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|24650171|ref|NP_651437.1| CG17370, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|23172328|gb|AAN14064.1| CG17370, isoform C [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0310535; name=SppL-PF; parent=FBgn0039381,FBtr0344118; dbxref=FlyBase:FBpp0310535,FlyBase_Annotation_IDs:CG17370-PF; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG17370 (CG17370, FBgn0039381). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21707707..21713286. It has the cytological map location 96F5-96F6. There is experimental evidence that it has the molecular function</span>: aspartic endopeptidase activity, intramembrane cleaving. There is experimental evidence that it is involved in the biological process</span>: membrane protein proteolysis. 9 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • >CG17370-PA translation from_gene[CG17370 CG17370 FBgn0039381] seq_release:3 mol_weight=45443 cds_boundaries:(3R:21,700,625..21,702,450[+]) aa_length:417 transcript_info:[CG17370-RA seq_release:3] gene_info:[gene symbol:CG17370 synonyms:[CG5901] FBgn00 [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG17370-PB translation from_gene[CG17370 CG17370 FBgn0039381] seq_release:3 mol_weight=45443 cds_boundaries:(3R:21,700,625..21,702,450[+]) aa_length:417 transcript_info:[CG17370-RB seq_release:3] gene_info:[gene symbol:CG17370 synonyms:[CG5901] FBgn00 [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG17370-PC translation from_gene[CG17370 CG17370 FBgn0039381] seq_release:3 mol_weight=45443 cds_boundaries:(3R:21,700,625..21,702,450[+]) aa_length:417 transcript_info:[CG17370-RC seq_release:3] gene_info:[gene symbol:CG17370 synonyms:[CG5901] FBgn00 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VBL1) CG17370-PA [DrosMelano7227.FASTAC.txt]
  • (AE003753) CG17370 gene product [alt 1] [Drosophila melanogaster] [yeastflysequest.fasta]
  • (AE003753) CG17370 gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG17370-PC, isoform C [Drosophila melanogaster]gi|7301395|gb|AAF56522.1| CG17370-PB, isoform B [Drosophila melanogaster]gi|7301394|gb|AAF56521.1| CG17370-PA, isoform A [Drosophila melanogaster]gi|24650175|ref|NP_733124.1| CG17370-PC [Drosophila melanog [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084283; name=CG17370-PA; parent=FBgn0039381,FBtr0084909; dbxref=FlyBase:FBpp0084283,FlyBase_Annotation_ID [fly-100309-contam.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084284; name=CG17370-PB; parent=FBgn0039381,FBtr0084910; dbxref=FlyBase:FBpp0084284,FlyBase_Annotation_ID [fly-100309-contam.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084285; name=CG17370-PC; parent=FBgn0039381,FBtr0084911; dbxref=FlyBase:FBpp0084285,FlyBase_Annotation_ID [fly-100309-contam.fasta]
  • CG17370-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG17370-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG17370-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084283; name=CG17370-PA; parent=FBgn0039381,FBtr0084909; dbxref=FlyBase:FBpp0084283,FlyBase_Annotation_IDs:CG17370-PA,GB_protein:AAF56521.1,REFSEQ:NP_651437,GB_protein:AAF56521; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084284; name=CG17370-PB; parent=FBgn0039381,FBtr0084910; dbxref=FlyBase:FBpp0084284,FlyBase_Annotation_IDs:CG17370-PB,GB_protein:AAF56522.1,REFSEQ:NP_733123,GB_protein:AAF56522; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084285; name=CG17370-PC; parent=FBgn0039381,FBtr0084911; dbxref=FlyBase:FBpp0084285,FlyBase_Annotation_IDs:CG17370-PC,GB_protein:AAN14064.1,REFSEQ:NP_733124,GB_protein:AAN14064; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084283; name=CG17370-PA; parent=FBgn0039381,FBtr0084909; dbxref=FlyBase:FBpp0084283,FlyBase_Annotation_IDs:CG17370-PA,GB_protein:AAF56521.1,REFSEQ:NP_651437,GB_protein:AAF56521; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084284; name=CG17370-PB; parent=FBgn0039381,FBtr0084910; dbxref=FlyBase:FBpp0084284,FlyBase_Annotation_IDs:CG17370-PB,GB_protein:AAF56522.1,REFSEQ:NP_733123,GB_protein:AAF56522; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084285; name=CG17370-PC; parent=FBgn0039381,FBtr0084911; dbxref=FlyBase:FBpp0084285,FlyBase_Annotation_IDs:CG17370-PC,GB_protein:AAN14064.1,REFSEQ:NP_733124,GB_protein:AAN14064; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG17370, isoform A OS=Drosophila melanogaster GN=CG17370 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084283; name=Sppl-PA; parent=FBgn0039381,FBtr0084909; dbxref=FlyBase:FBpp0084283,FlyBase_Annotation_IDs:CG17370-PA,GB_protein:AAF56521.1,REFSEQ:NP_651437,GB_protein:AAF56521; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084284; name=Sppl-PB; parent=FBgn0039381,FBtr0084910; dbxref=FlyBase:FBpp0084284,FlyBase_Annotation_IDs:CG17370-PB,GB_protein:AAF56522.1,REFSEQ:NP_733123,GB_protein:AAF56522,FlyMine:FBpp0084284,modMine:FBpp0084284; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:join(21711260..21711551,21711617..21711742,21712029..21712220,21712288..21712741,21712833..21712953,21713020..21713088); ID=FBpp0084285; name=Sppl-PC; parent=FBgn0039381,FBtr0084911; dbxref=FlyBase:FBpp0084285,FlyBase_Annotation_IDs:CG17370-PC,GB_protein:AAN14064.1,REFSEQ:NP_733124,GB_protein:AAN14064; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • CG17370, isoform A OS=Drosophila melanogaster GN=CG17370-RC PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084283; name=SppL-PA; parent=FBgn0039381,FBtr0084909; dbxref=FlyBase:FBpp0084283,FlyBase_Annotation_IDs:CG17370-PA,GB_protein:AAF56521.1,REFSEQ:NP_651437,GB_protein:AAF56521; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084284; name=SppL-PB; parent=FBgn0039381,FBtr0084910; dbxref=FlyBase:FBpp0084284,FlyBase_Annotation_IDs:CG17370-PB,GB_protein:AAF56522.1,REFSEQ:NP_733123,GB_protein:AAF56522,FlyMine:FBpp0084284,modMine:FBpp0084284; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084285; name=SppL-PC; parent=FBgn0039381,FBtr0084911; dbxref=FlyBase:FBpp0084285,FlyBase_Annotation_IDs:CG17370-PC,GB_protein:AAN14064.1,REFSEQ:NP_733124,GB_protein:AAN14064; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0310535; name=SppL-PF; parent=FBgn0039381,FBtr0344118; dbxref=GB_protein:AHN57534,REFSEQ:NP_001287535,FlyBase:FBpp0310535,FlyBase_Annotation_IDs:CG17370-PF; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084283; name=SppL-PA; parent=FBgn0039381,FBtr0084909; dbxref=FlyBase:FBpp0084283,FlyBase_Annotation_IDs:CG17370-PA,GB_protein:AAF56521.1,REFSEQ:NP_651437,GB_protein:AAF56521; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084284; name=SppL-PB; parent=FBgn0039381,FBtr0084910; dbxref=FlyBase:FBpp0084284,FlyBase_Annotation_IDs:CG17370-PB,GB_protein:AAF56522.1,REFSEQ:NP_733123,GB_protein:AAF56522,FlyMine:FBpp0084284,modMine:FBpp0084284; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084285; name=SppL-PC; parent=FBgn0039381,FBtr0084911; dbxref=FlyBase:FBpp0084285,FlyBase_Annotation_IDs:CG17370-PC,GB_protein:AAN14064.1,REFSEQ:NP_733124,GB_protein:AAN14064; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0310535; name=SppL-PF; parent=FBgn0039381,FBtr0344118; dbxref=GB_protein:AHN57534,REFSEQ:NP_001287535,FlyBase:FBpp0310535,FlyBase_Annotation_IDs:CG17370-PF; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q86P97, FI17310p1 OS=Drosophila melanogaster GN=SppL PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0084283 type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084283; name=SppL-PA; parent=FBgn0039381,FBtr0084909; dbxref=FlyBase:FBpp0084283,FlyBase_Annotation_IDs:CG17370-PA,GB_protein:AAF56521.1,REFSEQ:NP_651437,GB_protein:AAF56521; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0084284 type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084284; name=SppL-PB; parent=FBgn0039381,FBtr0084910; dbxref=FlyBase:FBpp0084284,FlyBase_Annotation_IDs:CG17370-PB,GB_protein:AAF56522.1,REFSEQ:NP_733123,GB_protein:AAF56522,FlyMine:FBpp0084284,modMine:FBpp0084284; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0084285 type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084285; name=SppL-PC; parent=FBgn0039381,FBtr0084911; dbxref=FlyBase:FBpp0084285,FlyBase_Annotation_IDs:CG17370-PC,GB_protein:AAN14064.1,REFSEQ:NP_733124,GB_protein:AAN14064; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0310535 type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0310535; name=SppL-PF; parent=FBgn0039381,FBtr0344118; dbxref=GB_protein:AHN57534,REFSEQ:NP_001287535,FlyBase:FBpp0310535,FlyBase_Annotation_IDs:CG17370-PF; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084283; name=SppL-PA; parent=FBgn0039381,FBtr0084909; dbxref=FlyBase:FBpp0084283,FlyBase_Annotation_IDs:CG17370-PA,GB_protein:AAF56521.1,REFSEQ:NP_651437,GB_protein:AAF56521,UniProt/TrEMBL:Q9VBL1; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084284; name=SppL-PB; parent=FBgn0039381,FBtr0084910; dbxref=FlyBase:FBpp0084284,FlyBase_Annotation_IDs:CG17370-PB,GB_protein:AAF56522.1,REFSEQ:NP_733123,GB_protein:AAF56522,UniProt/TrEMBL:Q9VBL1,FlyMine:FBpp0084284,modMine:FBpp0084284; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0084285; name=SppL-PC; parent=FBgn0039381,FBtr0084911; dbxref=FlyBase:FBpp0084285,FlyBase_Annotation_IDs:CG17370-PC,GB_protein:AAN14064.1,REFSEQ:NP_733124,GB_protein:AAN14064,UniProt/TrEMBL:Q9VBL1; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:join(25885538..25885829,25885895..25886020,25886307..25886498,25886566..25887019,25887111..25887231,25887298..25887366); ID=FBpp0310535; name=SppL-PF; parent=FBgn0039381,FBtr0344118; dbxref=GB_protein:AHN57534,REFSEQ:NP_001287535,FlyBase:FBpp0310535,FlyBase_Annotation_IDs:CG17370-PF,UniProt/TrEMBL:Q9VBL1; MD5=921b2d081d645c0988cd3c60d7f0e0d7; length=417; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 417 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: membrane protein proteolysis [IDA]
    Molecular Function: aspartic endopeptidase activity, intramembrane cleaving [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHGGAGGGL GAQTVGAGQL GGGAAAAGGG EYRELHWTVS SVMDSSRVST CLISMLLIVY  60
   61 GSFRSLNIEQ EAREREQKKR NESMTNLLTG EPVEKEPTDK FATLDTMHAL CLPLGASISL 120
  121 LIMFFFFDSM QLLFAVCTAI IATVALAFLL LPMCQYIIRP CTDGKRFSFG FCGRFTAAEL 180
  181 FSFTLSVSIV CIWVLTGHWL LMDAMGMGLC VAFIAFVRLP SLKVSTLLLT GLLIYDVFWV 240
  241 FLSSYIFSTN VMVKVATRPA DNPVGIVARK LHLGGIVRDT PKLNLPGKLV FPSLHNTGHF 300
  301 SMLGLGDVVM PGLLLCFVLR YDAYKKAQGV TSDPTLSPPR GVGSRLTYFH CSLLGYFLGL 360
  361 LTATVSSEVF KAAQPALLYL VPFTLLPLLL MAYLKGDLRR MWSEPFIAQQ PSKQLEV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] MSA 1.061985 View MSA. No confident structure predictions are available.
    2 View Details [117..309] MSA 3.081972 View MSA. No confident structure predictions are available.
    3 View Details [310..417] MSA 1.08099 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle