YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: CG4434-PA

General Information:
Name(s) found: CG4434-PA / FBpp0083774 [FlyBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • This gene is referred to in FlyBase by the symbol Dmel\CG4434 (CG4434, FBgn0039071). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19113939..19115911. It has the cytological map location 94E9. Based on sequence similarity, it is predicted to have molecular function</span>: glutamate dehydrogenase [NAD(P)+] activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: glutamate catabolic process to 2-oxoglutarate. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 535 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISS]
    Biological Process: glutamate catabolic process to 2-oxoglutarate [ISS]
    oxidation reduction [IEA]
    Molecular Function: glutamate dehydrogenase [NAD(P)+] activity [ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRYTARILN GIYPLMPRQV LKRSAHQVPE KLKKVETDKD PEFSEMVLYY YHKAAQTMEP  60
   61 ALLKEMEKYP HMKPEERQAR VTAILNLLGS VSTSVEVNFP IVRKNGTYEI ISGYRSHHVR 120
  121 HRLPLKGGIR YALDVNESEV KALAAIMTFK CACVNVPYGG SKGGICIDPK KYTVDELQTI 180
  181 TRRYTMELLK RNMIGPGIDV PAPDVNTGPR EMSWIVDQYQ KTFGYKDINS SAIVTGKPVH 240
  241 NGGINGRHSA TGRGVWKAGD LFLKDKEWMD LLKWKTGWKD KTVIVQGFGN VGSFAAKYVH 300
  301 EAGAKVIGIK EFDVSLVNKD GIDINDLFEY TEEKKTIKGY PKAQESKEDL LVAETDILMP 360
  361 CATQKVITTD NAKDIKAKLI LEGANGPTTP SGEKILLDKG VLLVPDLYCN AGGVTVSYFE 420
  421 YLKNINHVSY GKMNSKSTSE LIIELMNSIN ESLHECPDSQ LPNICPNKKL KRIQQCTTEA 480
  481 DIVDSALQTV MESAARGIKE MAHKFELCND LRRAAYVWSS FKIFQAMESS GISQQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..535] PSI-BLAST 153.0 Glutamate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutamate dehydrogenase (NADP+) activity
    		•  4.50065200228697 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  2.66329970371321 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  2.20121263385992 bayes_pls_golite062009
  • glutamate dehydrogenase [NAD(P)+] activity
    		•  2.15778057341677 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
    		•  2.00319512154556 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  1.81060491890041 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • DNA binding
    		•  1.61355789916908 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.55390653047158 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48478425318425 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • binding
    		•  0.982999356179965 bayes_pls_golite062009
  • transcription factor activity
    		•  0.91090893050278 bayes_pls_golite062009
  • transporter activity
    		•  0.793769336118517 bayes_pls_golite062009
  • structural molecule activity
    		•  0.75267483298133 bayes_pls_golite062009
  • steroid dehydrogenase activity
    		•  0.688300591674961 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  0.63606663166401 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.635891484075352 bayes_pls_golite062009
  • ethanol binding
    		•  0.60130343317805 bayes_pls_golite062009
  • receptor activity
    		•  0.591732115418164 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.565177620701637 bayes_pls_golite062009
  • retinol binding
    		•  0.52675367288453 bayes_pls_golite062009
  • protein binding
    		•  0.507836099271263 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.48368946932774 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.384212208916324 bayes_pls_golite062009
  • signal transducer activity
    		•  0.384212208916324 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.300373102236296 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.239024094835991 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.165260811069909 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.0992243118937675 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.0664389065992004 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.0257250793986203 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle