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Protein Overview: unk-PB, FBpp0294...

General Information:
Name(s) found: FBpp0294024 [FlyBase]
FBpp0294022 [FlyBase]
unk-PB / FBpp0083795 [FlyBase]
unk-PA / FBpp0083794 [FlyBase]
Description(s) found:
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  • gi|34395860|sp|Q86B79.1|UNK_DROME RecName: Full=RING finger protein unkempt [NCBI NR]
  • gi|28572106|ref|NP_788723.1| unkempt, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|28572104|ref|NP_788722.1| unkempt, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|28381434|gb|AAO41594.1| unkempt, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|28381433|gb|AAO41593.1| unkempt, isoform A [Drosophila melanogaster] [NCBI NR]
  • RING finger protein unkempt OS=Drosophila melanogaster GN=unk PE=1 SV=1 [Swiss-Prot]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0294024; name=unk-PE; parent=FBgn0004395,FBtr0305573; dbxref=REFSEQ:NP_001247255,GB_protein:AFH06573,FlyBase:FBpp0294024,FlyBase_Annotation_IDs:CG4620-PE; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0294022; name=unk-PC; parent=FBgn0004395,FBtr0305571; dbxref=REFSEQ:NP_001247253,GB_protein:AFH06571,FlyBase:FBpp0294022,FlyBase_Annotation_IDs:CG4620-PC; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.56; species=Dmel; [FlyBase]
  • The gene unkempt is referred to in FlyBase by the symbol Dmel\unk (CG4620, FBgn0004395). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18977275..18983592. It has the cytological map location 94E1-94E2. It is reported to have molecular function</span>: zinc ion binding; DNA binding. There is experimental evidence that it is involved in the biological process</span>: compound eye development; larval development; bristle morphogenesis; imaginal disc-derived wing morphogenesis. 12 alleles are reported. The phenotypes of these alleles are annotated with: embryonic head; scutellar bristle; wing; ommatidium. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG4620-PA translation from_gene[CG4620 unk FBgn0004395] seq_release:3 mol_weight=68443 cds_boundaries:(3R:18,970,322..18,974,222[-]) aa_length:599 transcript_info:[CG4620-RA seq_release:3] gene_info:[gene symbol:unk FBgn0004395 gene_boundaries:(3R:18, [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG4620-PB translation from_gene[CG4620 unk FBgn0004395] seq_release:3 mol_weight=68443 cds_boundaries:(3R:18,970,322..18,974,222[-]) aa_length:599 transcript_info:[CG4620-RB seq_release:3] gene_info:[gene symbol:unk FBgn0004395 gene_boundaries:(3R:18, [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q86B79) Unkempt protein [DrosMelano7227.FASTAC.txt]
  • CG4620-PB, isoform B [Drosophila melanogaster]gi|28381433|gb|AAO41593.1| CG4620-PA, isoform A [Drosophila melanogaster]gi|28572106|ref|NP_788723.1| CG4620-PB [Drosophila melanogaster]gi|28572104|ref|NP_788722.1| CG4620-PA [Drosophila melanogaster]gi|3 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0083794; name=unk-PA; parent=FBgn0004395,FBtr0084402; dbxref=FlyBase:FBpp0083794, [fly-100309-contam.fasta]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0083795; name=unk-PB; parent=FBgn0004395,FBtr0084403; dbxref=FlyBase:FBpp0083795, [fly-100309-contam.fasta]
  • Protein unkempt [nr-271106-contam.fasta]
  • CG4620-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • unkempt CG4620-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG4620-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • unkempt CG4620-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0083794; name=unk-PA; parent=FBgn0004395,FBtr0084402; dbxref=FlyBase:FBpp0083794,FlyBase_Annotation_IDs:CG4620-PA,GB_protein:AAO41593.1,REFSEQ:NP_788722,GB_protein:AAO41593; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0083795; name=unk-PB; parent=FBgn0004395,FBtr0084403; dbxref=FlyBase:FBpp0083795,FlyBase_Annotation_IDs:CG4620-PB,GB_protein:AAO41594.1,REFSEQ:NP_788723,GB_protein:AAO41594; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0083794; name=unk-PA; parent=FBgn0004395,FBtr0084402; dbxref=FlyBase:FBpp0083794,FlyBase_Annotation_IDs:CG4620-PA,GB_protein:AAO41593.1,REFSEQ:NP_788722,GB_protein:AAO41593; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0083795; name=unk-PB; parent=FBgn0004395,FBtr0084403; dbxref=FlyBase:FBpp0083795,FlyBase_Annotation_IDs:CG4620-PB,GB_protein:AAO41594.1,REFSEQ:NP_788723,GB_protein:AAO41594; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0083794; name=unk-PA; parent=FBgn0004395,FBtr0084402; dbxref=FlyBase:FBpp0083794,FlyBase_Annotation_IDs:CG4620-PA,GB_protein:AAO41593.1,REFSEQ:NP_788722,GB_protein:AAO41593,FlyMine:FBpp0083794,modMine:FBpp0083794; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0083795; name=unk-PB; parent=FBgn0004395,FBtr0084403; dbxref=FlyBase:FBpp0083795,FlyBase_Annotation_IDs:CG4620-PB,GB_protein:AAO41594.1,REFSEQ:NP_788723,GB_protein:AAO41594; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0294022; name=unk-PC; parent=FBgn0004395,FBtr0305571; dbxref=REFSEQ:NP_001247253,GB_protein:AFH06571,FlyBase:FBpp0294022,FlyBase_Annotation_IDs:CG4620-PC; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(18979662..18979859,18979916..18980496,18980567..18980689,18981531..18981733,18981796..18982215,18983223..18983432,18983501..18983565); ID=FBpp0294024; name=unk-PE; parent=FBgn0004395,FBtr0305573; dbxref=REFSEQ:NP_001247255,GB_protein:AFH06573,FlyBase:FBpp0294024,FlyBase_Annotation_IDs:CG4620-PE; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0083794; name=unk-PA; parent=FBgn0004395,FBtr0084402; dbxref=FlyBase:FBpp0083794,FlyBase_Annotation_IDs:CG4620-PA,GB_protein:AAO41593.1,REFSEQ:NP_788722,GB_protein:AAO41593,FlyMine:FBpp0083794,modMine:FBpp0083794; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0083795; name=unk-PB; parent=FBgn0004395,FBtr0084403; dbxref=FlyBase:FBpp0083795,FlyBase_Annotation_IDs:CG4620-PB,GB_protein:AAO41594.1,REFSEQ:NP_788723,GB_protein:AAO41594; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0294022; name=unk-PC; parent=FBgn0004395,FBtr0305571; dbxref=REFSEQ:NP_001247253,GB_protein:AFH06571,FlyBase:FBpp0294022,FlyBase_Annotation_IDs:CG4620-PC; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0294024; name=unk-PE; parent=FBgn0004395,FBtr0305573; dbxref=REFSEQ:NP_001247255,GB_protein:AFH06573,FlyBase:FBpp0294024,FlyBase_Annotation_IDs:CG4620-PE; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0083794; name=unk-PA; parent=FBgn0004395,FBtr0084402; dbxref=FlyBase:FBpp0083794,FlyBase_Annotation_IDs:CG4620-PA,GB_protein:AAO41593.1,REFSEQ:NP_788722,GB_protein:AAO41593,FlyMine:FBpp0083794,modMine:FBpp0083794; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0083795; name=unk-PB; parent=FBgn0004395,FBtr0084403; dbxref=FlyBase:FBpp0083795,FlyBase_Annotation_IDs:CG4620-PB,GB_protein:AAO41594.1,REFSEQ:NP_788723,GB_protein:AAO41594; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0294022; name=unk-PC; parent=FBgn0004395,FBtr0305571; dbxref=REFSEQ:NP_001247253,GB_protein:AFH06571,FlyBase:FBpp0294022,FlyBase_Annotation_IDs:CG4620-PC; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0294024; name=unk-PE; parent=FBgn0004395,FBtr0305573; dbxref=REFSEQ:NP_001247255,GB_protein:AFH06573,FlyBase:FBpp0294024,FlyBase_Annotation_IDs:CG4620-PE; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q86B79, Unkempt, isoform C OS=Drosophila melanogaster GN=unk PE=4 SV=1 [DROME.fasta.20160308]
  • FBpp0083794 type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0083794; name=unk-PA; parent=FBgn0004395,FBtr0084402; dbxref=FlyBase:FBpp0083794,FlyBase_Annotation_IDs:CG4620-PA,GB_protein:AAO41593.1,REFSEQ:NP_788722,GB_protein:AAO41593,FlyMine:FBpp0083794,modMine:FBpp0083794; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0083795 type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0083795; name=unk-PB; parent=FBgn0004395,FBtr0084403; dbxref=FlyBase:FBpp0083795,FlyBase_Annotation_IDs:CG4620-PB,GB_protein:AAO41594.1,REFSEQ:NP_788723,GB_protein:AAO41594; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0294022 type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0294022; name=unk-PC; parent=FBgn0004395,FBtr0305571; dbxref=REFSEQ:NP_001247253,GB_protein:AFH06571,FlyBase:FBpp0294022,FlyBase_Annotation_IDs:CG4620-PC; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0294024 type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0294024; name=unk-PE; parent=FBgn0004395,FBtr0305573; dbxref=REFSEQ:NP_001247255,GB_protein:AFH06573,FlyBase:FBpp0294024,FlyBase_Annotation_IDs:CG4620-PE; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0083794; name=unk-PA; parent=FBgn0004395,FBtr0084402; dbxref=FlyBase:FBpp0083794,FlyBase_Annotation_IDs:CG4620-PA,GB_protein:AAO41593.1,REFSEQ:NP_788722,GB_protein:AAO41593,UniProt/Swiss-Prot:Q86B79,FlyMine:FBpp0083794,modMine:FBpp0083794; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0083795; name=unk-PB; parent=FBgn0004395,FBtr0084403; dbxref=FlyBase:FBpp0083795,FlyBase_Annotation_IDs:CG4620-PB,GB_protein:AAO41594.1,REFSEQ:NP_788723,GB_protein:AAO41594,UniProt/Swiss-Prot:Q86B79; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0294022; name=unk-PC; parent=FBgn0004395,FBtr0305571; dbxref=REFSEQ:NP_001247253,GB_protein:AFH06571,FlyBase:FBpp0294022,FlyBase_Annotation_IDs:CG4620-PC,UniProt/Swiss-Prot:Q86B79; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:complement(join(23157779..23157843,23157501..23157710,23156074..23156493,23155809..23156011,23154845..23154967,23154194..23154774,23153940..23154137)); ID=FBpp0294024; name=unk-PE; parent=FBgn0004395,FBtr0305573; dbxref=REFSEQ:NP_001247255,GB_protein:AFH06573,FlyBase:FBpp0294024,FlyBase_Annotation_IDs:CG4620-PE,UniProt/Swiss-Prot:Q86B79; MD5=fc5d40f110287451441aa9bc96714d20; length=599; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 599 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    Biological Process: bristle morphogenesis [IMP]
    imaginal disc-derived wing morphogenesis [IMP]
    larval development [IMP]
    compound eye development [IMP]
    Molecular Function: nucleic acid binding [IEA]
    DNA binding [NAS]
    zinc ion binding [IEA][NAS]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLANETNKLL LSSQQEKPNH YTYLKEFRVE QCQSFLQHKC NQHRPFVCFN WHFQNQRRRR  60
   61 PVRKRDGTFN YSADNYCTKY DETTGICPEG DECPYLHRTA GDTERRYHLR YYKTCMCVHD 120
  121 TDSRGYCVKN GLHCAFAHGM QDQRPPVYDI KELETLQNAE STLDSTNALN ALDKERNLMN 180
  181 EDPKWQDTNY VLANYKTEPC KRPPRLCRQG YACPQYHNSK DKRRSPRKYK YRSTPCPNVK 240
  241 HGEEWGEPGN CEAGDNCQYC HTRTEQQFHP EIYKSTKCND VQQAGYCPRS VFCAFAHVEP 300
  301 CSMDDPRENS LSASLANTSL LTRSSAPINI PNTTLSNSIN DFNSGSFAVN IPSSSLTYSP 360
  361 TNHANLFNVD AFNYGGSNKL SNSLSATQND SSLFFPSRII SPGFGDGLSI SPSVRISELN 420
  421 TIRDDINSSS VGNSLFENTL NTAKNAFSLQ SLQSQNNSDL GRITNELLTK NAQIHKLNGR 480
  481 FEDMACKLKI AELHRDKAKQ EAQEWKERYD LAQIQLNLPA ELRDLSIQKL KQLQSKLRTD 540
  541 LEEVDKVLYL ENAKKCMKCE ENNRTVTLEP CNHLSICNTC AESVTECPYC QVPVITTHT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] PSI-BLAST 6.522879 Structural Basis for Recognition of the mRNA Class II AU-Rich Element by the Tandem Zinc Finger Domain of TIS11d
    2 View Details [157..351] FFAS03 1.74 No description for 2e5sA was found.
    3 View Details [352..415] deduced N/A No confident structure predictions are available.
    4 View Details [416..517] FFAS03 1.02 BAG-family molecular chaperon regulator-1, BAG1
    5 View Details [518..599] PSI-BLAST 5.30103 Cbl; N-terminal domain of cbl (N-cbl); CBL

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.34058618645939 bayes_pls_golite062009
  • protein binding
    		•  1.25788087676809 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle