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Protein Overview: KaiRIA-PA

General Information:
Name(s) found: KaiRIA-PA / FBpp0083346 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene KaiRIA is referred to in FlyBase by the symbol Dmel\KaiRIA (CG18039, FBgn0028422). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16474311..16478172. It has the cytological map location 92F4. Based on sequence similarity, it is predicted to have molecular function</span>: ionotropic glutamate receptor activity; kainate selective glutamate receptor activity. There is experimental evidence that it is involved in the biological process</span>: neuromuscular synaptic transmission; rhythmic excitation. 10 alleles are reported. The phenotypes of these alleles are annotated with: NMJ bouton; neuromuscular junction; larval neuromuscular junction. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 902 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    ionotropic glutamate receptor complex [ISS]
    Biological Process: ion transport [IEA]
    neuromuscular synaptic transmission [IMP]
    rhythmic excitation [IMP]
    Molecular Function: kainate selective glutamate receptor activity [ISS]
    ionotropic glutamate receptor activity [IEA][ISS]
    extracellular-glutamate-gated ion channel activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHFCWISLII LSLSRVQAQF YGGNAYEASS GQSIRLGLIT DDATDRIRQT FEHAISVVNN  60
   61 ELGVPLVGET EQVAYGNSVQ AFAQLCRLMQ SGVGAVFGPA ARHTASHLLN ACDSKDIPFI 120
  121 YPHLSWGSNP DGFNLHPSPE DIANALYDIV NQFEWSRFIF CYESAEYLKI LDHLMTRYGI 180
  181 KGPVIKVMRY DLNLNGNYKS VLRRIRKSED SRIVVVGSTT GVAELLRQAQ QVGIMNEDYT 240
  241 YIIGNLNLHT FDLEEYKYSE ANITGIRMFS PDQEEVRDLM EKLHQELGES EPVNSGSTFI 300
  301 TMEMALTYDA VRVIAETTKH LPYQPQMLNC SERHDNVQPD GSTFRNYMRS LEIKEKTITG 360
  361 RIYFEGNVRK GFTFDVIELQ TSGLVKVGTW EEGKDFEFQR PPQAVNFNDI DDGSLVNKTF 420
  421 IVLISVATKP YASLVESIDT LIGNNQFQGY GVDLIKELAD KLGFNFTFRD GGNDYGSFNK 480
  481 TTNSTSGMLK EIVEGRADLA ITDLTITSER EEVIDFSIPF MNLGIAILYV KPQKAPPALF 540
  541 SFMDPFSSEV WLYLGIAYLG VSLCFFIIGR LSPIEWDNPY PCIEEPEELE NQFTINNSLW 600
  601 FTTGALLQQG SEIAPKALST RTISAIWWFF TLIMVSSYTA NLAAFLTIEN PTSPINSVKD 660
  661 LADNKDDVQY GAKRTGSTRN FFSTSEEPIY IKMNEYLNAH PEMLMENNQQ GVDKVKSGTK 720
  721 YAFLMESTSI EFNTVRECNL TKVGDPLDEK GYGIAMVKNW PYRDKFNKAL LELQEQGVLA 780
  781 RLKNKWWNEV GAGVCSAKSD DDGPSELGVD NLSGIYVVLV IGSIISIIIS ILCWCYFVYK 840
  841 KAKNYEVPFC DALAEEFRIV IRFSENERPL KSAQSIYSRS RNSSQSIESL KTDSEENMPV 900
  901 ED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..495] PSI-BLAST 40.522879 No description for 2e4uA was found.
    2 View Details [496..647] FFAS03 1.36 No description for 2qksA was found.
    3 View Details [648..801] PSI-BLAST 28.39794 Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
    4 View Details [802..902] MSA 1.349993 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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