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Protein Overview: CG4159-PA

General Information:
Name(s) found: CG4159-PA / FBpp0083351 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4159 (CG4159, FBgn0038811). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16416746..16418393. It has the cytological map location 92F2. Based on sequence similarity, it is predicted to have molecular function</span>: pseudouridylate synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: pseudouridine synthesis. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 410 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: pseudouridine synthesis [IEA]
    Molecular Function: RNA binding [IEA]
    pseudouridine synthase activity [IEA]
    pseudouridylate synthase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEALDKLEV EKEARKEAKE LEGEAVKDAN RIKRTLKRKK WVDWKEQDEK DAANGVKRAP  60
   61 FDPADRIKRK KSAILLSYCG ANYYGMQRNP GMQTIEEELF KAMLKHKWIT EDSFEQIQIS 120
  121 CFQRAARTDK GVSAARQVCS VKLPEELDLE AFNADLPQQI RLFGVERVTK GFNAKDQCNA 180
  181 RTYTYTLPTV AFAPFEEKVD DVHDTFRISP ELLQKVKETL KLYEGTKNFH NFTSKKSFLD 240
  241 PSSKRFIMSF TSSEPFRSPQ DIEFVTLKVK GQSFMLHQIR KMVGLAIAIV RGNTTAATLE 300
  301 RALTEERLDL PMAPGLGLVL DTVHYERYND RYGKDGIHNP LTWQAQEAQV QEFIEREIFS 360
  361 QIYKTEAEQR NMLDWIGTLH YHSYDTRTED APPPSSEDKK VKGGDDDNDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..334] PSI-BLAST 78.69897 No description for 2nqpA was found.
    2 View Details [335..410] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pseudouridine synthase activity
    		•  5.19957135839682 bayes_pls_golite062009
  • intramolecular transferase activity
    		•  3.78688422405974 bayes_pls_golite062009
  • isomerase activity
    		•  2.91720316078381 bayes_pls_golite062009
  • catalytic activity
    		•  2.02180970970004 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.71767925225399 bayes_pls_golite062009
  • binding
    		•  1.41741633277343 bayes_pls_golite062009
  • DNA binding
    		•  1.12055110308252 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.01148651898043 bayes_pls_golite062009
  • RNA binding
    		•  0.195784910723548 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle