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Protein Overview: CG42668-PD

General Information:
Name(s) found: CG42668-PD / FBpp0291806 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG42668 (CG42668, FBgn0261550). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16135925..16149918. It has the cytological map location 92E2. Based on sequence similarity, it is predicted to have molecular function</span>: oxysterol binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: steroid metabolic process. 4 alleles are reported. No phenotypic data is available. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 625 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: steroid metabolic process [IEA]
    Molecular Function: oxysterol binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYPSAKYPL QYSAFVPVRQ AGNYTLIFAR FRLLKKYLDA DSQNEAPNAV MSGLESESES  60
   61 DPAEPAQDDV VDQQCVETSY VPFTEEEFGE QGEQVEELAE ENKSLIWCIV KQVRPGMDLS 120
  121 KVVLPTFILE PRSFLDKLSD SYYHADLLSK AVQEDDAFTR MKLVVQWYLS SFYKKPKGLK 180
  181 KPYNPILGER FRCYWQHPSG SRTFYIAEQV SHHPPVSAFY VTNREDGFSI TCSILAKSKF 240
  241 YGNSTSAVLE GAATMTLLPR GECYTATTPY AHCKGILMGT LSMELGGKIN IECENTGYRT 300
  301 ELEFKLKPFL GGADATNVVV GKIKLGKETL ATINGHWDKE CRVKDSKTGE ETVLFKVDAE 360
  361 TRSKRLTRYM VPLDLQEANE SQRLWQRVSE AIANEDQVAA TEEKTVLEER QRADAKERLS 420
  421 SDSVHMPDLF ELDSYGQWLY KYADLRPWDS RNDVRQYECQ FKVLTQTRHK SVPIVHGAEM 480
  481 IHPLRSSIET LSRTQRQSPA GQPLPPGGSA VPKAKNKSLV LAPRDTNSDS SQSPQGAVKR 540
  541 SSSSAIKQLA LAVDQVNRVL EQHTRQLNEI SQRLERMQYS PPPSSMSAHS LHMLGGGVSQ 600
  601 STVIKSLIYA LIGLAFSLIL RWLFK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..81] deduced N/A No confident structure predictions are available.
    2 View Details [82..450] PSI-BLAST 78.154902 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
    3 View Details [451..625] MSA 1.136974 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • binding
    		•  1.67154210149282 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
  • oxysterol binding
    		•  1.1738554488982 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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