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Protein Overview: Indy-2-PB, Indy-2-PA

General Information:
Name(s) found: Indy-2-PB / FBpp0099667 [FlyBase]
Indy-2-PA / FBpp0099666 [FlyBase]
Description(s) found:
Found 35 descriptions.
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  • The gene I'm not dead yet 2 is referred to in FlyBase by the symbol Dmel\Indy-2 (CG33933, FBgn0260466). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15868479..15874438. It has the cytological map location 92C3-92C4. Based on sequence similarity, it is predicted to have molecular function</span>: sodium:dicarboxylate symporter activity; pyruvate transmembrane transporter activity; citrate transmembrane transporter activity; succinate transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: succinate transport; transport; citrate transport; determination of adult lifespan; pyruvate transport. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene I'm not dead yet 2 is referred to in FlyBase by the symbol Dmel\Indy-2 (CG33933, FBgn0260466). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15868479..15874438. It has the cytological map location 92C3-92C4. Based on sequence similarity, it is predicted to have molecular function</span>: sodium:dicarboxylate symporter activity; pyruvate transmembrane transporter activity; citrate transmembrane transporter activity; succinate transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: succinate transport; transport; citrate transport; determination of adult lifespan; pyruvate transport. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 562 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [ISS]
    Biological Process: sodium ion transport [IEA]
    transmembrane transport [IEA]
    pyruvate transport [ISS]
    determination of adult lifespan [ISS]
    citrate transport [ISS]
    transport [ISS]
    succinate transport [ISS]
    Molecular Function: citrate transmembrane transporter activity [ISS]
    succinate transmembrane transporter activity [ISS]
    sodium:dicarboxylate symporter activity [ISS]
    pyruvate transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPGEQRKF VLGRCCIFHW RGKASIIIPL ITLPILIYGF QTDMAEFKCL WLIVTMALLW  60
   61 ITETLPIYVT ALFPLVFCPL LGLVNASIVC KQYFTDTIVV FLGGLIVALG IEYSNLHTRI 120
  121 ALRVIRIVGG SPRRLFVGLM SVSTFMGLWI SNSAGTAMMC PIVKALVNEL DTNKIFPVYM 180
  181 TQEEEPVEEG EPPHPSKITV AFYAGIAYAS SIGGLGTLIG TGTNLVFRGI YTERFPTSTV 240
  241 EITFANFMFY SIPLMVIVNV TLVIIAFLIT HMGLFRPNSK TGKIIAEANT NRKLMEDVLR 300
  301 QRHIDLGPMS CHEIQMAIAF AFMIVLLITR KPGFVPGWSD LINRKVVGSA SGLSFIVLLI 360
  361 FALPTQYTFF KYCCGKGPFT AQAIDAILSW EYVLRNIPWG LLFLLGGGFA LAVASRETGL 420
  421 NIMISKAMQV LIGLPNIVVQ SITFVLANFF SAFNANVVVA NIVLPILCEM SLALELHPLI 480
  481 LTLPACLGIS MVYFLPVSTP PNAIVTQYAH IKTKYFACCG IVPTIIGISV ALVNTNTWGL 540
  541 IIFPESKSFP DWAKEIKNQT KI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..176] MSA 3.442979 View MSA. No confident structure predictions are available.
    2 View Details [177..342] deduced N/A No confident structure predictions are available.
    3 View Details [343..562] MSA 14.519997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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