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Protein Overview: CG4459-PA

General Information:
Name(s) found: CG4459-PA / FBpp0083258 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4459 (CG4459, FBgn0038753). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15752158..15754317. It has the cytological map location 92B8. Based on sequence similarity, it is predicted to have molecular function</span>: secondary active organic cation transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 632 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: transmembrane transport [IEA]
    Molecular Function: secondary active organic cation transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDSQSMGSI PRKSSPELDV VEQVNGSFGR WQLRTILLIF LCKIPSAWFT AIIIYTAPYP  60
   61 WKGELVCHPA DWNVSRSQTE HVDRNHPLWQ DARSTDRLFN VDVCNAYSNS LARGFVRSHG 120
  121 QEWNASQSKE PGGQSSLPCE HVEHRTDYKS LISQFDLICS RRVLVALTQS FHALGALIGG 180
  181 LMAYSALKKI SPRRLMLLGM IGQIFCGNLT GLVDTYQLHI YFRCLTSIFC ALMYTSGQFI 240
  241 LNDITSGKAR IIVVTLSELF WSMGLVLLPA ISIYFDNWSY LYVAISSSLI VLVWLHRWIA 300
  301 DAPRWLLQHQ RVEAALRQLL ESATYNNRKV PLTLDVQLTM YANDLDQKSK QKHSYCQVWD 360
  361 GETKRSQLVY IHLIWGGAMV LYNIILLMIR NLGAQQVHVN TAAMGFAEMV GLFVGLYLIL 420
  421 YTRRHWRWAG NLMIIAGLST YLIWLLPETE RNSRRVGLEL VFWLILKIAN SASIAVLTTC 480
  481 TSEIVSKEKR VVLMLSVISF SRVCLLFCPF LSCLTVIHHL VPITILATMG WIYGLALRRL 540
  541 NRYYWNTEQP QISQVPTPNT YRRQSAIILR RCSTVSSDCS AYSNELLSNF ERNMAVSIAD 600
  601 IWHINFHPSS EIEMEVEQSG PEAHRAHSSE TI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..117] deduced N/A No confident structure predictions are available.
    2 View Details [118..554] PSI-BLAST 27.221849 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
    3 View Details [555..632] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  3.3413526350788 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  2.52916479889426 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.10195430930703 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.10195430930703 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • binding
    		•  1.46605775041083 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  0.312628600969375 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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