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Protein Overview: FBpp0310730, Rho...

General Information:
Name(s) found: FBpp0310730 [FlyBase]
RhoGAP92B-PA / FBpp0083230 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=3R:join(15731033..15731082,15731353..15731609,15734156..15734331,15736615..15737581,15738034..15738806); ID=FBpp0310730; name=RhoGAP92B-PE; parent=FBgn0038747,FBtr0344354; dbxref=FlyBase:FBpp0310730,FlyBase_Annotation_IDs:CG4755-PE; MD5=3d2a1f304ee8851f1827b0010df4308b; length=740; release=r5.56; species=Dmel; [FlyBase]
  • The gene RhoGAP92B is referred to in FlyBase by the symbol Dmel\RhoGAP92B (CG4755, FBgn0038747). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15730861..15739455. It has the cytological map location 92B6. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: signal transduction. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 740 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: signal transduction [IEA]
    Molecular Function: protein binding [IEA]
    GTPase activator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRQFAKIKI AAENLSRSSK SDSKDSELEA IERQVDRYRD TIEKIVRKLP ALSGGGGSGS  60
   61 GSSEEQDKRT KKNSHYKIAQ ALDESAKELP KDMPLQKVLA NCGELEKTMA ECIIESELET 120
  121 EAKVVRRLKN ILDKEIQEIS TLKRNVSRTL QEYTSLKRSH EAAIRLEEPA AKVNHIKSQQ 180
  181 EECELKLEKE RDAWAAQMLE LIAKEDEIVS CIRDYVLNQR NYHERALQHV NASLARIQDT 240
  241 IQGTEKSRFG TSLKEHLTST NREISYIVEL CCCCLLEHGL EEEGLLRVGC ASTKLRRMKH 300
  301 ALEAQHVKTP LPLDYQDPHV IGSILKLYLR ELPEPLLTYN LYKDFIRIAE RHSEAERKTE 360
  361 IKAILTKLPK ENYANLRYLT RFLSIVQQRS ALNKMSSQNL AIVMSPNMLW PRIDKSSNAP 420
  421 ADYIGQVNSS SAANIIVELL ISQWDYFFIG EVEFYLTLQK QKLFVEGKSK SNSSNENLDR 480
  481 NDSEVMESPR YGTLRRQKAN APSPPTTNGN GIIMTTSQTS HRPHAKELFP QQTPEKQEKP 540
  541 AKPPLPNLPQ FQSPAASQPT QTQLEPLPPP PVTPAKPVPM TRTQFFGLDN LPSPTADRKS 600
  601 TDSIGSFKLK PDVPQKPLLP KRPTVLGVGV PKADGKSDDE GGTTPTQATI DNGNGSVRFK 660
  661 TEHFLDKLRQ ENGETNGTRE VSSTTKENNH NHDPPATAAD QNQQQAQPQV TTPISPNSFQ 720
  721 TPKRPTVPAP PPPTNWKSSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..486] PSI-BLAST 61.09691 Crystal Structure of the Human Beta2-Chimaerin
    2 View Details [487..598] deduced N/A No confident structure predictions are available.
    3 View Details [599..740] MSA 11.290996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • enzyme activator activity
    		•  0.53004209819211 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.528693496432149 bayes_pls_golite062009
  • binding
    		•  0.0980674097362609 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  0.0454578418356197 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle