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View Structure Prediction Details

Protein: FBpp0310730, Rho...
Organism: Drosophila melanogaster
Length: 740 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0310730, Rho....

Description E-value Query
Range
Subject
Range
RHG44_MOUSE - Rho GTPase-activating protein 44 OS=Mus musculus GN=Arhgap44 PE=1 SV=1
390.0 [0..1] [738..1]

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Predicted Domain #1
Region A:
Residues: [1-486]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRQFAKIKI AAENLSRSSK SDSKDSELEA IERQVDRYRD TIEKIVRKLP ALSGGGGSGS  60
   61 GSSEEQDKRT KKNSHYKIAQ ALDESAKELP KDMPLQKVLA NCGELEKTMA ECIIESELET 120
  121 EAKVVRRLKN ILDKEIQEIS TLKRNVSRTL QEYTSLKRSH EAAIRLEEPA AKVNHIKSQQ 180
  181 EECELKLEKE RDAWAAQMLE LIAKEDEIVS CIRDYVLNQR NYHERALQHV NASLARIQDT 240
  241 IQGTEKSRFG TSLKEHLTST NREISYIVEL CCCCLLEHGL EEEGLLRVGC ASTKLRRMKH 300
  301 ALEAQHVKTP LPLDYQDPHV IGSILKLYLR ELPEPLLTYN LYKDFIRIAE RHSEAERKTE 360
  361 IKAILTKLPK ENYANLRYLT RFLSIVQQRS ALNKMSSQNL AIVMSPNMLW PRIDKSSNAP 420
  421 ADYIGQVNSS SAANIIVELL ISQWDYFFIG EVEFYLTLQK QKLFVEGKSK SNSSNENLDR 480
  481 NDSEVM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.09691
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
enzyme activator activity 0.53004209819211 bayes_pls_golite062009
GTPase activator activity 0.528693496432149 bayes_pls_golite062009
binding 0.0980674097362609 bayes_pls_golite062009
Ras GTPase activator activity 0.0454578418356197 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [487-598]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPRYGTLRR QKANAPSPPT TNGNGIIMTT SQTSHRPHAK ELFPQQTPEK QEKPAKPPLP  60
   61 NLPQFQSPAA SQPTQTQLEP LPPPPVTPAK PVPMTRTQFF GLDNLPSPTA DR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [599-740]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSTDSIGSFK LKPDVPQKPL LPKRPTVLGV GVPKADGKSD DEGGTTPTQA TIDNGNGSVR  60
   61 FKTEHFLDKL RQENGETNGT REVSSTTKEN NHNHDPPATA ADQNQQQAQP QVTTPISPNS 120
  121 FQTPKRPTVP APPPPTNWKS SD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle