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Protein Overview: Cpsf73-PA

General Information:
Name(s) found: Cpsf73-PA / FBpp0083105 [FlyBase]
Description(s) found:
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  • gi|24648013|ref|NP_650738.1| CG7698 [Drosophila melanogaster] [NCBI NR]
  • gi|23171662|gb|AAF55578.2| CG7698 [Drosophila melanogaster] [NCBI NR]
  • gi|21430620|gb|AAM50988.1| RE31408p [Drosophila melanogaster] [NCBI NR]
  • Cleavage and polyadenylation specificity factor 73 OS=Drosophila melanogaster GN=Cpsf73 PE=1 SV=2 [Swiss-Prot]
  • The gene Cleavage and polyadenylation specificity factor 73 is referred to in FlyBase by the symbol Dmel\Cpsf73 (CG7698, FBgn0261065). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14486843..14489250. It has the cytological map location 91B8. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: hydrolase activity. There is experimental evidence that it is involved in the biological process</span>: histone mRNA 3'-end processing. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG7698-PA translation from_gene[CG7698 CG7698 FBgn0038636] seq_release:3 mol_weight=76827 cds_boundaries:(3R:14,486,901..14,489,194[-]) aa_length:684 transcript_info:[CG7698-RA seq_release:3] gene_info:[gene symbol:CG7698 FBgn0038636 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VE51) CG7698 protein (RE31408p) [DrosMelano7227.FASTAC.txt]
  • CG7698-PA [Drosophila melanogaster]gi|21430620|gb|AAM50988.1| RE31408p [Drosophila melanogaster]gi|24648013|ref|NP_650738.1| CG7698-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(14486881..14486970,14487034..14487476,14487538..14488829,14488892..14489053,14489110..14489177); ID=FBpp0083105; name=CG7698-PA; parent=FBgn0038636,FBtr0083690; dbxref=FlyBase:FBpp0083105,FlyBase_Annotation_IDs:CG7698-PA,GB [fly-100309-contam.fasta]
  • CG7698-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE31408p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(14486881..14486970,14487034..14487476,14487538..14488829,14488892..14489053,14489110..14489177); ID=FBpp0083105; name=CG7698-PA; parent=FBgn0038636,FBtr0083690; dbxref=FlyBase:FBpp0083105,FlyBase_Annotation_IDs:CG7698-PA,GB_protein:AAF55578.2,REFSEQ:NP_650738,GB_protein:AAF55578; MD5=561027f5c8acaec5d590c2c8c2a96c01; length=684; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(14486881..14486970,14487034..14487476,14487538..14488829,14488892..14489053,14489110..14489177); ID=FBpp0083105; name=Cpsf73-PA; parent=FBgn0261065,FBtr0083690; dbxref=FlyBase:FBpp0083105,FlyBase_Annotation_IDs:CG7698-PA,GB_protein:AAF55578.2,REFSEQ:NP_650738,GB_protein:AAF55578; MD5=561027f5c8acaec5d590c2c8c2a96c01; length=684; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(14486881..14486970,14487034..14487476,14487538..14488829,14488892..14489053,14489110..14489177); ID=FBpp0083105; name=Cpsf73-PA; parent=FBgn0261065,FBtr0083690; dbxref=FlyBase:FBpp0083105,FlyBase_Annotation_IDs:CG7698-PA,GB_protein:AAF55578.2,REFSEQ:NP_650738,GB_protein:AAF55578,FlyMine:FBpp0083105,modMine:FBpp0083105; MD5=561027f5c8acaec5d590c2c8c2a96c01; length=684; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • Cleavage and polyadenylation specificity factor 73 OS=Drosophila melanogaster GN=Cpsf73 PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3R:complement(join(18663388..18663455,18663170..18663331,18661816..18663107,18661312..18661754,18661159..18661248)); ID=FBpp0083105; name=Cpsf73-PA; parent=FBgn0261065,FBtr0083690; dbxref=FlyBase:FBpp0083105,FlyBase_Annotation_IDs:CG7698-PA,GB_protein:AAF55578.2,REFSEQ:NP_650738,GB_protein:AAF55578,FlyMine:FBpp0083105,modMine:FBpp0083105; MD5=561027f5c8acaec5d590c2c8c2a96c01; length=684; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(18663388..18663455,18663170..18663331,18661816..18663107,18661312..18661754,18661159..18661248)); ID=FBpp0083105; name=Cpsf73-PA; parent=FBgn0261065,FBtr0083690; dbxref=FlyBase:FBpp0083105,FlyBase_Annotation_IDs:CG7698-PA,GB_protein:AAF55578.2,REFSEQ:NP_650738,GB_protein:AAF55578,FlyMine:FBpp0083105,modMine:FBpp0083105; MD5=561027f5c8acaec5d590c2c8c2a96c01; length=684; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0083105 type=protein; loc=3R:complement(join(18663388..18663455,18663170..18663331,18661816..18663107,18661312..18661754,18661159..18661248)); ID=FBpp0083105; name=Cpsf73-PA; parent=FBgn0261065,FBtr0083690; dbxref=FlyBase:FBpp0083105,FlyBase_Annotation_IDs:CG7698-PA,GB_protein:AAF55578.2,REFSEQ:NP_650738,GB_protein:AAF55578,FlyMine:FBpp0083105,modMine:FBpp0083105; MD5=561027f5c8acaec5d590c2c8c2a96c01; length=684; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(18663388..18663455,18663170..18663331,18661816..18663107,18661312..18661754,18661159..18661248)); ID=FBpp0083105; name=Cpsf73-PA; parent=FBgn0261065,FBtr0083690; dbxref=FlyBase:FBpp0083105,FlyBase_Annotation_IDs:CG7698-PA,GB_protein:AAF55578.2,REFSEQ:NP_650738,GB_protein:AAF55578,UniProt/Swiss-Prot:Q9VE51,FlyMine:FBpp0083105,modMine:FBpp0083105; MD5=561027f5c8acaec5d590c2c8c2a96c01; length=684; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 684 amino acids

    Gene Ontology:
    Cellular Component: mRNA cleavage and polyadenylation specificity factor complex [ISS][NAS]
    Biological Process: histone mRNA 3'-end processing [IMP]
    mRNA polyadenylation [ISS]
    mRNA cleavage [ISS]
    Molecular Function: hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQATGDARM PDEESDLLQI KPLGAGQEVG RSCIMLEFKG KKIMLDCGIH PGLSGMDALP  60
   61 YVDLIEADEI DLLFISHFHL DHCGALPWFL MKTSFKGRCF MTHATKAIYR WMLSDYIKIS 120
  121 NISTEQMLYT EADLEASMEK IETINFHEER DVMGVRFCAY IAGHVLGAAM FMIEIAGIKI 180
  181 LYTGDFSRQE DRHLMAAEVP PMKPDVLITE STYGTHIHEK REDRENRFTS LVQKIVQQGG 240
  241 RCLIPVFALG RAQELLLILD EFWSQNPDLH EIPIYYASSL AKKCMAVYQT YINAMNDRIR 300
  301 RQIAVNNPFV FRHISNLKGI DHFEDIGPCV IMASPGMMQS GLSRELFESW CTDPKNGVII 360
  361 AGYCVEGTLA KAVLSEPEEI TTLSGQKLPL NMSVDYISFS AHTDYQQTSE FIRLLKPTHV 420
  421 VLVHGEQNEM SRLKLALQRE YEADASTDIK FYNPRNTHAV DLYFRGEKTA KVMGSLAAKN 480
  481 SEVGSKLSGV LVKRDFKYHL LAPSDLGKYT DMSMSVVTQR QSIPWGSSLS TLELLLDRIG 540
  541 AGCVEVLEAE RKLRVFGCIE LTVEQKIIVM EWQATHVNDV YADAVLACIM QSELGGTNLK 600
  601 GATKQTKSED SRFRECLIET LQDTFGDNCV PKMFEGDLLP VTVSGKRAEI NLETLAISCA 660
  661 EDDVLRQMLN TTVQKLHQTL VSAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..465] PSI-BLAST 102.0 No description for 2i7tA was found.
    2 View Details [466..684] MSA 2.227973 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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