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Protein Overview: sr-PA

General Information:
Name(s) found: sr-PA / FBpp0082966 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene stripe is referred to in FlyBase by the symbol Dmel\sr (CG7847, FBgn0003499). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:13916525..13959471. It has the cytological map location 90E4-90F1. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; ectoderm development; somatic muscle development; germ-band shortening; muscle organ development; epithelial cell migration, open tracheal system; phagocytosis, engulfment. 61 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; peripheral nervous system; portion of tissue; embryonic/larval tracheal system; nervous system; primordium; adult; germ layer; extended germ band embryo; adult somatic muscle. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1186 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    intracellular [IEA]
    Biological Process: muscle organ development [IMP]
    epithelial cell migration, open tracheal system [IGI][IMP]
    central nervous system development [IMP]
    phagocytosis, engulfment [IMP]
    germ-band shortening [IMP]
    pigment metabolic process [TAS]
    ectoderm development [IMP]
    regulation of transcription [ISS]
    somatic muscle development [IMP]
    determination of muscle attachment site [TAS]
    Molecular Function: nucleic acid binding [IEA]
    zinc ion binding [IEA]
    RNA polymerase II transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLTMRRQNE LIVGSQQHPS ATSSASSSAG ATSSPGLSGQ NLNLVAGAGA ATNSTSANSQ  60
   61 DSLNTPTTPL LGLSRNPLQF APPPAPPIAV PNPAASGPTF GYYQTVNAAP PIHHSPAATS 120
  121 EVSTAPQPPV ELDEYVDILQ VQQLLLDSSA AAAAAANNPP TTEQSVQQPQ QNTVVQPHPH 180
  181 QQQQQQQQQQ QPQQQQQQPQ QILAKPRPRI NLQKATEYAA QLAQAESSSP GSRRVLLDYP 240
  241 SPYLYGNPYH HHTPPGEDLV ALWFGSNGTG GVAPGTPSAA MIMEGLETLV APTHHAFLLT 300
  301 ETAAAAHFNV LSFDTCLFKT STAAQSSGSP STATYLSPAQ FGGSHHGGAS TSSNSLNSSS 360
  361 TASSSSTSSS LLHYTTASAA AAAAAAAAAS ANNSVLRARN QTATPTQGGS PGHVAVQPSA 420
  421 TASSGRSSAS HLSLLNTSGQ HSPTSSAVEQ VEAHKQLIEA LPGDLNTPVT TSSDIPSFFG 480
  481 PTTVVEPPPI TGSIESEDLS LEPQVISVAS PVLSHCSPLK EERSTPPALA IVKEESSNNS 540
  541 CNMYPQHNNN NNNNNNTTSS STTTTSKQTT SESNTECVGS PGNHTQSHQQ QQQQLQHNNT 600
  601 SSSNSNCHHS HQQQQQQQQQ QHMSSPQQQY QQHQILHQQQ QLPNHHHHHH HHHHHHSQLQ 660
  661 QLQQQQQQQQ QQQQHQQQPL HQQQQLQHQQ QQQHHQQHYQ QHAIQHQQSQ QQASKISYRG 720
  721 IFTTTGNAMN AAAAAAAAAA QQQHQQQQQH QQQLPSPQLG VLAGPMSPPS NSLGNSWGLP 780
  781 SPDKTMFQPP LFSLPAHYAT MQQQQQQQQQ QQQQQQQQQA AGAAPSPYDD GRAAAAAAAQ 840
  841 HAELLGLTMD CTPLLLKQPP PSYAGASAGF PGLGDLHSSH EQQLQQQQYV RSQPKYQWLD 900
  901 SPADYAQQQQ QVQQVQQQQQ QQQTLVLPGP TSSASSSNAA LGVLIPKQEN YPDMQPSSNG 960
  961 TGYSGGSGGS SAAAAAAAAA AAAAVQLAEY SPSTSKGHEI LSQVYQQSTV PLKLVPVKPR1020
 1021 KYPNRPSKTP VHERPYACPV ENCDRRFSRS DELTRHIRIH TGQKPFQCRI CMRSFSRSDH1080
 1081 LTTHIRTHTG EKPFSCDICG RKFARSDEKK RHAKVHLKQR IKKEKVRGEQ QQQQQQQQQQ1140
 1141 QQQQQQQQLQ QQQEQHHLSL QQHQQYQQHH LLHSADLAIV TSSASM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..491] FFAS03 2.1 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
    2 View Details [492..646] MSA 1.294976 View MSA. No confident structure predictions are available.
    3 View Details [647..761] deduced N/A No confident structure predictions are available.
    4 View Details [762..952] deduced N/A No confident structure predictions are available.
    5 View Details [953..1186] PSI-BLAST 62.30103 No description for 2i13A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.27

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle