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Protein Overview: Pak3-PA, FBpp0293540

General Information:
Name(s) found: FBpp0293540 [FlyBase]
Pak3-PA / FBpp0082763 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=3R:complement(12276923..12278632); ID=FBpp0293540; name=Pak3-PC; parent=FBgn0044826,FBtr0305003; dbxref=REFSEQ:NP_732141,GB_protein:AAN13710,FlyBase:FBpp0293540,FlyBase_Annotation_IDs:CG14895-PC; MD5=a329af757e46638a08d60432a93f59e6; length=569; release=r5.56; species=Dmel; [FlyBase]
  • The gene Pak3 is referred to in FlyBase by the symbol Dmel\Pak3 (CG14895, FBgn0044826). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12272450..12279550. It has the cytological map location 89B16-89B17. It is reported to have molecular function</span>: receptor signaling protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: actin filament organization. 13 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 569 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: actin filament organization [IMP]
    protein amino acid phosphorylation [IEA][NAS]
    Molecular Function: ATP binding [IEA]
    receptor signaling protein serine/threonine kinase activity [NAS]
    protein serine/threonine kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFTKWFKKK GGDGGSISEI GAPTNFQRHF HVSRNQETGD LEGLPAPWVR LMNSQITRDE  60
   61 QDKNPDAAYH AVKYYNYSIK KKENEVFKPF ITEDVIHEES KEIENYVNYK NKHKSQDPEK 120
  121 SDDDGSSTAT ETESSSGCGS SAGNSNSSSI NDSSQQSTVP LDALEEVFKE LKTNLEHRET 180
  181 LKAAPQEPPP VPPKKSPHTI PPKPQIKPKP RVTQKFSRTS DIRRDEDSDN QHKINTDTII 240
  241 IKPAVGAQDA GADDNPDETI LRRSKEKRAQ KTDAEIYVEL RAICNSDDPR ERYKTTQEVG 300
  301 KGASGIVFIA ADLQNESQVA VKTIDMKNQS SKDLILTEIR VLKDFNHKNL VNFLDAYLLE 360
  361 PEDQLWVVME YMDGGPLTDV VTETVMKERQ IACVCRETLY AISFLHAKGI IHRDIKSDNV 420
  421 LLGMDGSVKV TDFGFCANIE GDEKRQTMVG TPYWMAPEVV TRKKYGKKVD IWSIGIMAIE 480
  481 MIEGQPPYLY ETPLRALYLI AANGRPDIKS WDKLSPNLQD FLDRCLQVEV DRRATADELL 540
  541 SHPFLNDCSE VKALVPNIKA AKKVLRRNV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] PSI-BLAST 19.30103 pak1 autoregulatory domain
    2 View Details [87..267] deduced N/A No confident structure predictions are available.
    3 View Details [268..569] PSI-BLAST 82.69897 pak1


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle