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View Structure Prediction Details

Protein: Pak3-PA, FBpp0293540
Organism: Drosophila melanogaster
Length: 569 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pak3-PA, FBpp0293540.

Description E-value Query
Range
Subject
Range
gi|25012334 - gi|25012334|gb|AAN71278.1| RE01659p [Drosophila melanogaster]
408.0 [0..1] [569..1]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFTKWFKKK GGDGGSISEI GAPTNFQRHF HVSRNQETGD LEGLPAPWVR LMNSQITRDE  60
   61 QDKNPDAAYH AVKYYNYSIK KKENEV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.30103
Match: 1f3mA
Description: pak1 autoregulatory domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [87-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKPFITEDVI HEESKEIENY VNYKNKHKSQ DPEKSDDDGS STATETESSS GCGSSAGNSN  60
   61 SSSINDSSQQ STVPLDALEE VFKELKTNLE HRETLKAAPQ EPPPVPPKKS PHTIPPKPQI 120
  121 KPKPRVTQKF SRTSDIRRDE DSDNQHKINT DTIIIKPAVG AQDAGADDNP DETILRRSKE 180
  181 K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [268-569]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RAQKTDAEIY VELRAICNSD DPRERYKTTQ EVGKGASGIV FIAADLQNES QVAVKTIDMK  60
   61 NQSSKDLILT EIRVLKDFNH KNLVNFLDAY LLEPEDQLWV VMEYMDGGPL TDVVTETVMK 120
  121 ERQIACVCRE TLYAISFLHA KGIIHRDIKS DNVLLGMDGS VKVTDFGFCA NIEGDEKRQT 180
  181 MVGTPYWMAP EVVTRKKYGK KVDIWSIGIM AIEMIEGQPP YLYETPLRAL YLIAANGRPD 240
  241 IKSWDKLSPN LQDFLDRCLQ VEVDRRATAD ELLSHPFLND CSEVKALVPN IKAAKKVLRR 300
  301 NV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 82.69897
Match: 1f3mC
Description: pak1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle