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Protein Overview: Manf-PA

General Information:
Name(s) found: Manf-PA / FBpp0082735 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Mesencephalic astrocyte-derived neurotrophic factor is referred to in FlyBase by the symbol Dmel\Manf (CG7013, FBgn0027095). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12175088..12176523. It has the cytological map location 89B13. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: neuron homeostasis; neuron projection development. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 173 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IDA][NAS]
    Biological Process: neuron homeostasis [IMP]
    neuron projection development [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTWYMVVVI GFLATLAQTS LALKEEDCEV CVKTVRRFAD SLDDSTKKDY KQIETAFKKF  60
   61 CKAQKNKEHR FCYYLGGLEE SATGILNELS KPLSWSMPAE KICEKLKKKD AQICDLRYEK 120
  121 QIDLNSVDLK KLKVRDLKKI LNDWDESCDG CLEKGDFIKR IEELKPKYSR SEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..173] FFAS03 1.18 Crystal Structure of a FYVE-type domain from caspase regulator CARP2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.561606449522564 bayes_pls_golite062009
  • receptor binding
    		•  0.177430744933542 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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