Protein Overview: MRG15-PA

General Information:
Name(s) found:	MRG15-PA / FBpp0082579 [FlyBase]
Description(s) found: Found 26 descriptions. SHOW ALL	The gene MRG15 is referred to in FlyBase by the symbol Dmel\MRG15 (CG6363, FBgn0027378). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11102162..11103831. It has the cytological map location 88E11. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: chromatin binding. There is experimental evidence that it is involved in the biological process</span>: chromatin silencing. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	424 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA][NAS] chromatin [IEA]
Biological Process:	chromatin assembly or disassembly [IEA] chromatin silencing [IMP]
Molecular Function:	chromatin binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEVKPAKVE NYSTGTDANT LFVDGERVLC FHGPLIYEAK VLKTKPDATP VEYYIHYAGW  60
   61 SKNWDEWVPE NRVLKYNDDN VKRRQELARQ CGERSKKDNK KGSAKAKKME QMRNESRAST 120
  121 PSKDSNTSQS TASSTPTTSA GPGSKSEAGS TGTTTTNSTA NSTTSRAHRK STQSTPSTAR 180
  181 PGTPSDKKED PAAAETTEEE GPVAPKKKRM SEQRPSLTGS DVAEKPLPPT TTPSTPTTEP 240
  241 APCVESEEAY AAKVEVKIKI PDELKHYLTD DWYAVVREHK LLELPAKVTV QQISEQYLAH 300
  301 KKSVKSTSAS KEVAINDVLD GIVEYFNVML GSQLLYKFER TQYADVMQKH PDTPLSELYG 360
  361 SFHLLRLFVR LGSMLSYSAL DQQSMQNLLT HVQDFLKFLV KNSSIFFSMS NFINVDPEYV 420
  421 RNAQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
transcription repressor activity	4.08500855631983	bayes_pls_golite062009
transcription regulator activity	3.64390820819794	bayes_pls_golite062009
chromatin binding	3.1924157640698	bayes_pls_golite062009
binding	3.06758476214113	bayes_pls_golite062009
nucleic acid binding	2.19167058827256	bayes_pls_golite062009
DNA binding	2.05514577638135	bayes_pls_golite062009
protein binding	1.61683263008775	bayes_pls_golite062009
histone binding	1.37812404837999	bayes_pls_golite062009
methylated histone residue binding	0.79088613483042	bayes_pls_golite062009
general transcriptional repressor activity	0.75184432495983	bayes_pls_golite062009
transcription corepressor activity	0.294457188332415	bayes_pls_golite062009
catalytic activity	0.14067200158938	bayes_pls_golite062009
transcription activator activity	0.136090220479238	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..113]	PSI-BLAST	24.522879	No description for 2efiA was found.
2	View Details	[114..247]	FFAS03	1.71	No description for 2j63A was found.
3	View Details	[248..424]	PSI-BLAST	63.69897	Crystal Structure of the MRG15 MRG domain

Protein Overview: MRG15-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: